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Large US study finds never-married adults face higher risk for most major cancers

A large US population-based study found that never-married adults had higher cancer incidence than ever-married adults across most cancer types, with the largest disparities seen in older adults and in Black men. The pattern was especially strong for HPV-related, tobacco-related, and several reproductive cancers, suggesting marital status may act as an important social marker of cancer risk.

9 Apr 2026

Never married adults face higher risk of developing cancer

Adults who have never been married face a significantly higher risk of developing cancer than those who have been married, according to a large U.S. study of more than 4 million cases.

8 Apr 2026

Metformin boosts an exercise-linked metabolite and may help control weight in prostate cancer patients

Metformin raised the exercise-linked metabolite Lac-Phe in prostate cancer patients across disease stages and treatment settings, while Lac-Phe itself did not predict anticancer response. Patients in the BIMET-1 metformin arm also showed better weight management during anti-androgen therapy, highlighting a possible metabolic benefit relevant to prostate cancer care.

7 Apr 2026

New technique can simultaneously treat lung cancer and muscle-wasting condition

Researchers at Oregon State University have developed a technique for simultaneously treating lung cancer and a serious muscle-wasting condition that often accompanies it.

6 Apr 2026

New target identified to overcome resistance in neuroendocrine tumors

Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells.

6 Apr 2026

Metformin mimics exercise-related metabolic effects in prostate cancer patients

A new study has found that metformin, a widely prescribed diabetes drug, may mimic one of exercise's core biological effects in men with prostate cancer, raising levels of a molecule tied to energy balance and weight control even when patients are inactive.

6 Apr 2026

New dual drugs eliminate tumors when combined with immunotherapy

Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, first-in-class drugs that inhibit hypoxia-inducible factors 1 and 2, a pair of transcription factors considered to be "master regulators" of cancer progression.

2 Apr 2026

PSMA therapy may postpone hormone treatment in prostate cancer patients

Where previous research showed that PSMA therapy for prostate cancer can prolong the lives of patients who have exhausted all other treatment options, a new study now demonstrates that the therapy is also effective in an earlier stage of the disease.

30 Mar 2026

ATLAS platform enables realistic study of metastatic cancer clusters

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part because researchers lack reliable ways to recreate the conditions cancer cells encounter as they travel through the bloodstream.

26 Mar 2026

Men show major gaps in male fertility knowledge, study finds

A study of 156 adult men found that knowledge about male fertility was generally low across both medical and lifestyle-related topics, with only 5 of 25 questions answered correctly by most respondents. Older men, those with a medical background, and those with suspected or treated infertility tended to score higher, while supplement use was common despite limited fertility literacy.

26 Mar 2026

Estradiol patches as effective as injections for locally advanced prostate cancer

Hormone patches are as good at controlling locally advanced prostate cancer as the injections typically used to deliver hormone therapy, according to the results of a large clinical trial led by UCL (University College London) researchers.

25 Mar 2026

Blood pressure drug boosts effectiveness of cancer therapy

In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP, investigators found that the FDA-approved blood pressure drug telmisartan can significantly enhance the cancer-killing activity of the targeted therapy olaparib, potentially expanding its use to many more patients.

25 Mar 2026

Detailed cell atlas reveals earliest changes in prostate cancer

Prostate cancer affects one in five Australian men, making it the most common cancer in the country.

25 Mar 2026

Systematic review identifies stress-induced biological triggers in oncology

Stress is a constant companion in the oncologist's office. It appears at the time of diagnosis, increases with each stage of treatment, and often does not resolve even after therapy formally ends. It accompanies therapeutic decisions, waiting for test results, fear of recurrence, and changes in daily functioning. Studies show that chronic stress can trigger biological processes that promote disease progression and weaken the body's defenses.

25 Mar 2026

CREB5 drives stem cell-like transcriptional programs in aggressive prostate cancer

A new research paper was published in Volume 17 of Oncotarget on March 17, 2026, titled "CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer."

24 Mar 2026

Research reveals potential new strategy for targeting deadly small cell neuroendocrine cancers

UCLA researchers have uncovered a hidden weakness in some of the deadliest cancers, revealing a potential new strategy for targeting tumors that have long resisted treatment.

23 Mar 2026

Large-scale study finds no link between psychosocial factors and cancer risk

New research indicates that psychosocial factors-which influence how a person perceives, interprets, and reacts to their surroundings-do not affect an individual's risk of developing cancer. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

23 Mar 2026