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Research reveals crucial role of saturated fatty acids in memory creation process

Researchers at the University of Queensland have revealed the crucial role of saturated fatty acids in the brain's consolidation of memories.

5 Feb 2024

Shared molecular pathways found in Alzheimer's and epilepsy

Study reveals shared brain proteomic signatures in Alzheimer’s disease and epilepsy, suggesting common molecular mechanisms that could pave the way for unified therapeutic strategies.

5 Feb 2024

New approach offers hope for regaining lost memories in Alzheimer's

While newly approved drugs for Alzheimer's show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory.

1 Feb 2024

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings

Members of the AD-RIDDLE consortium announced today that they will begin a new initiative that aims to bridge the gap between Alzheimer's research, implementation science, and precision medicine.

31 Jan 2024

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells.

30 Jan 2024

Research reveals the function of a little-understood junction between brain cells

New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma.

12 Jan 2024

Researchers discover PPFIA3 gene as a cause of previously unknown syndromic neurodevelopmental disorder

An international collaborative study led by postdoctoral scientist, Dr. Maimuna Paul, and child neurologist, Dr. Hsiao-Tuan Chao, an assistant professor at Baylor College, a faculty member with the Cain Pediatric Neurology Research Foundation Laboratories at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, and an investigator at the McNair Medical Institute with The Robert and Janice McNair Foundation, recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic neurodevelopmental disorder.

4 Jan 2024

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester find that microglia - the brain's immune cells - can trigger cognitive deficits after radiation exposure and may be a key target for preventing these symptoms.

3 Jan 2024

Patient-specific muscle models pave way for personalized neuromuscular therapies

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

19 Dec 2023

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Researchers performed a proteomic analysis to identify serologic indicators of organ aging and disease.

7 Dec 2023

IU researchers uncover novel mechanism of pathogen entry into cells

Similar to a burglar breaking a window to get into a house, Indiana University researchers have discovered a previously unknown process by which pathogens enter a cell with physical force, breaching the body's immune defenses that prevent infection.

1 Dec 2023

Dissecting how co-transmission of interneurons helps in odor detection and discrimination

A longstanding hypothesis in neurobiology was that a single neuron releases a single type of neurotransmitter, a molecule used by neurons to communicate with one another.

28 Nov 2023

Researchers discover mechanism for memory storage in engram cells

What is the mechanism that allows our brains to incorporate new information about the world, and form memories? New work by a team of neuroscientists led by Dr Tomás Ryan from Trinity College Dublin shows that learning occurs through the continuous formation of new connectivity patterns between specific engram cells in different regions of the brain.

22 Nov 2023

Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

Inhibitory interneurons play a crucial role in fear memory expression and recall

Memory, a fundamental tool for our survival, is closely linked with how we encode, recall, and respond to external stimuli.

8 Nov 2023

DZNE neuroscientist awarded 1.5 million euros to investigate biophysical phenomena relevant to brain diseases

Dr. Dragomir Milovanovic, a neuroscientist at DZNE's Berlin site, has been awarded an European Research Council (ERC) "Starting Grant" worth 1.5 million euros to investigate biophysical phenomena relevant to brain diseases in a groundbreaking research project.

7 Nov 2023

TIMP2 protein identified as key player in brain plasticity and memory

Researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix (ECM) of the adult brain hippocampus.

6 Nov 2023

Marijuana's psychoactive compound may alter brain wiring in adolescents

In a mouse study designed to explore the impact of marijuana's major psychoactive compound, THC, on teenage brains, Johns Hopkins Medicine researchers say they found changes to the structure of microglia, which are specialized brain immune cells, that may worsen a genetic predisposition to schizophrenia.

25 Oct 2023

Immune system proteins play role in early stages of Huntington's disease

Huntington's Disease is the most common neurodegenerative disorder controlled by a single gene and is characterized by motor and cognitive deficits and psychiatric symptoms.

12 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.