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Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations.

16 Aug 2016

Scientists discover key molecule that drives regeneration in planarian stem cells

Many living creatures possess exceptional abilities that set them apart from other species. Cheetahs can run up to 60 miles per hour; ants can lift 100 times their body weight; flatworms can regrow amputated body parts.

12 Aug 2016

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in the journal Cancer Discovery.

11 Aug 2016

New research examines biomechanics of galectin-3

A new study, published in Biochemistry this week, examines the biomechanics of sugar-seeking proteins. Specifically, it delves into galectin-3's interaction with glycosaminoglycans (GAG) and proteoglycans.

5 Aug 2016

New research aims to understand, manage contact lens discomfort

Do you have dry eyes or other symptoms related to wearing contact lenses? If so you're not alone—up to 50 percent of contact lens wearers experience dryness or discomfort at least occasionally.

3 Aug 2016

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer's survival and spread.

3 Aug 2016

Advances in head and neck cancer treatments: an interview with Prof. Argiris

Patients with head and neck cancer usually present with locally advanced disease and often require more than one type of treatment, which may include surgery, radiotherapy, and chemotherapy.

3 Aug 2016

Blood pressure hormone system important for cardiovascular health can promote obesity

New research by University of Iowa scientists helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity.

29 Jul 2016

Updated guidelines for breast cancer increase number of patients who test HER2-positive

Changes to HER2 testing guidelines for breast cancer in 2013 significantly increased the number of patients who test HER2-positive, according to a new study by Mayo Clinic researchers published in the Journal of Clinical Oncology.

28 Jul 2016

Researchers find potential way for delivering gene therapy to treat eye diseases

Eye diseases such as diabetic retinopathy and age-related macular degeneration are among the leading causes of irreversible vision loss and blindness worldwide. Currently, gene therapy can be administered to treat these conditions -- but this requires an injection.

27 Jul 2016

Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Three manuscripts published in the recent issue of the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer, explored the versatility of liquid biopsies by identifying EGFR mutations using circulating tumor DNA (ctDNA) in urine and plasma and examining circulating tumor cells (CTCs) in plasma to predict the risk of lung cancer recurrence after surgical resection.

26 Jul 2016

Embryonic stem cell gene Nanog holds potential for reversing effects of aging

The fountain of youth may reside in an embryonic stem cell gene named Nanog.

26 Jul 2016

Adding new monoclonal antibody to chemotherapy improves survival in soft-tissue sarcoma patients

Adding a novel monoclonal antibody therapy to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, a lethal soft-tissue cancer.

21 Jul 2016

Protein present on stem cell surface can boost growth of damaged muscle tissue

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.

19 Jul 2016

IU researchers create virtual tissue model of diabetic retinopathy

By combining data on optometry patient's eyes with advanced computational methods, Indiana University researchers have created a virtual tissue model of diabetes in the eye.

15 Jul 2016

Penn study provides more insights into cardiovascular side effects of breast cancer drug

A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

14 Jul 2016

Phase III clinical study of promising prostate cancer drug reveals surprising results

A recently published international clinical Phase III trial of a promising drug for treating advanced prostate cancer ended with surprising results: the new therapeutic agent failed to achieve any significant improvement in the overall survival of patients compared with the established standard treatment.

12 Jul 2016

Mussels inspire scientists to attach biologically active molecule to titanium surface

Titanium is used medically in applications such as artificial joints and dental implants. While it is strong and is not harmful to tissues, the metal lacks some of the beneficial biological properties of natural tissues such as bones and natural teeth.

11 Jul 2016

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Like pancreatic cancer, cancer of the ovaries is notorious for being discovered at a relatively late stage - after it has spread to other sites in the body. It is not called "the silent killer" for nothing.

11 Jul 2016

New topical film patch can effectively close dermal wounds, reduce scarring

Currently there is no product available based on polymer film containing active molecules to accelerate dermal wound healing that also reduces the scar formation.

8 Jul 2016

Growth Factor News and Research

Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Scientists discover key molecule that drives regeneration in planarian stem cells

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

New research examines biomechanics of galectin-3

New research aims to understand, manage contact lens discomfort

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Advances in head and neck cancer treatments: an interview with Prof. Argiris

Blood pressure hormone system important for cardiovascular health can promote obesity

Updated guidelines for breast cancer increase number of patients who test HER2-positive

Researchers find potential way for delivering gene therapy to treat eye diseases

Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Embryonic stem cell gene Nanog holds potential for reversing effects of aging

Adding new monoclonal antibody to chemotherapy improves survival in soft-tissue sarcoma patients

Protein present on stem cell surface can boost growth of damaged muscle tissue

IU researchers create virtual tissue model of diabetic retinopathy

Penn study provides more insights into cardiovascular side effects of breast cancer drug

Phase III clinical study of promising prostate cancer drug reveals surprising results

Mussels inspire scientists to attach biologically active molecule to titanium surface

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

New topical film patch can effectively close dermal wounds, reduce scarring

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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