Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

Diabetes knowledge has little effect on improving outcomes

A new study by Duke Clinical Research Institute researchers finds little relationship between what a diabetic patient knows about the disease and control of its associated cardiovascular risk factors or how well the patient ultimately fares.

3 Jun 2005

Genetic variation alters response to anti-clotting drug warfarin

Millions of people take the anticoagulant drug warfarin to prevent harmful clotting after a heart attack, stroke, or major surgery. But the proper dose of warfarin can vary greatly and can be hard to predict.

1 Jun 2005

Diabetics more sensitive to cardiovascular effects from air pollution

People with diabetes may be at higher risk for cardiovascular problems when air pollution levels are higher, according to a new study of Boston-area residents. The ability of the blood vessels to control blood flow was impaired in adults with diabetes on days with elevated levels of particles from traffic and coal-burning power plants.

31 May 2005

Under prescribing of statins puts more people at risk of premature death

A new study out of Stanford School of Medicine says that cholesterol-lowering drugs known as statins that can help prevent heart disease are still underprescribed for many at-risk patients.

31 May 2005

Fluorescence device to diagnose atherosclerosis and tumors

In a presentation at the Conference on Lasers and Electro-Optics (CLEO), researchers from Cedars-Sinai Medical Center's Biophotonics Research and Technology Development Laboratory described recent progress on a device that stimulates, collects and measures light emissions from body tissues to diagnose critical atherosclerotic plaques (vulnerable plaques) and aggressive brain tumors.

29 May 2005

One in five patients hospitalized for heart attack experiences a major depression

According to the Hopkins cardiologists who conducted the study, these depressed patients are 50 percent more likely than other heart attack patients to need hospital care for a heart problem again within a year and three times as likely to die from a future attack or other heart-related conditions.

26 May 2005

New study shows that bypass surgery is more successful than stents in heart surgery

A study of nearly 60,000 patients has found that people with several clogged heart arteries did better if they had bypass surgery rather than a less-drastic procedure in which the blood vessels are propped open with tiny mesh cylinders called stents.

26 May 2005

'Bad' metabolism cloggs up arteries

Scientists are now saying that a 'bad' metabolism may explain why some people who have never smoked and do not have high cholesterol levels suffer from a potentially lethal build-up of plaque in the arteries.

26 May 2005

Increase in heart surgery mortality from SSRIs or depression?

Duke University Medical Center researchers have found that patients who were using a class of anti-depression drugs known as selective serotonin reuptake inhibitors (SSRI) prior to undergoing coronary artery bypass surgery have significantly higher death and rehospitalization rates up to five years after the procedure than patients who were not on SSRIs.

26 May 2005

HIPAA privacy rule makes it harder, costlier to do research that improves the quality of medical care

New research reveals a clash between two of the biggest issues in health care today: protecting individual patients' privacy and improving the quality, safety and cost of medical care for all patients.

26 May 2005

Most serious side effects in statins may be higher in one of the newest drugs, rosuvastatin (Crestor)

A post-market analysis of cholesterol-lowering drugs called statins indicates that some of the most serious side effects may be higher in one of the newest drugs, rosuvastatin (Crestor). The drug is the strongest statin available because it has the greatest effect per milligram on low-density lipoprotein ("bad" cholesterol).

26 May 2005

Study shows how COX-2 inhibitors lead to heart disease

University of Pennsylvania School of Medicine researchers have found additional evidence that may help explain how selective inhibitors of COX-2 might predispose individuals to heart disease and stroke.

26 May 2005

Patients with metabolic syndrome and moderate calcium levels in the coronary arteries have greater chance of blocked arteries

Conditions such as abdominal obesity, high blood pressure, abnormal cholesterol levels and high blood sugar are problematic enough for people all on their own.

26 May 2005

A diet rich in milk does not increase the risk of heart disease and stroke

The research team asked a representative sample of 764 men to weigh and record every item of food and drink they consumed for seven consecutive days. Just under 90% of the sample (665) produced complete and detailed diaries.

24 May 2005

New cholesterol drug Crestor causes safety concerns

A study by a leading medical journal has concluded that AstraZeneca's controversial drug Crestor produces more than twice as many side effects as other common cholesterol lowering treatments.

24 May 2005

Metabolic syndrome prevalent in heart attack patients

Nearly half of heart attack patients also met criteria for metabolic syndrome, putting them at a higher risk for development of heart failure, according to an article in the May 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

23 May 2005

Within six months, one in three patients fail to take cardiovascular risk-lowering medications as prescribed

Therapy that includes medications to reduce high blood pressure and to lower lipid levels can reduce risk for heart disease, but within six months, more than a third of patients fail to take one or both medications as prescribed, according to a study in the May 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

23 May 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, UCSF medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

23 May 2005

Chest CT can be first step to identifying if patient has had a heart attack

When radiologists are looking at contrast-enhanced chest CT examinations, they should take a look at the patient's heart to rule out heart attack, regardless of why the chest CT examination is being performed, a new study shows.

20 May 2005

Cystatin-C, a new blood test for kidney function, is a better predictor of death and cardiovascular risk among the elderly

Investigators for NHLBI's Cardiovascular Health Study compared the two measures of kidney function, cystatin-C and the standard test creatinine, as predictors of death from all causes, death from cardiovascular causes, and incidence of heart attack and stroke among 4,637 elderly participants in the study.

20 May 2005

Heart Attack (Myocardial Infarction) News and Research

Further Reading

Diabetes knowledge has little effect on improving outcomes

Genetic variation alters response to anti-clotting drug warfarin

Diabetics more sensitive to cardiovascular effects from air pollution

Under prescribing of statins puts more people at risk of premature death

Fluorescence device to diagnose atherosclerosis and tumors

One in five patients hospitalized for heart attack experiences a major depression

New study shows that bypass surgery is more successful than stents in heart surgery

'Bad' metabolism cloggs up arteries

Increase in heart surgery mortality from SSRIs or depression?

HIPAA privacy rule makes it harder, costlier to do research that improves the quality of medical care

Most serious side effects in statins may be higher in one of the newest drugs, rosuvastatin (Crestor)

Study shows how COX-2 inhibitors lead to heart disease

Patients with metabolic syndrome and moderate calcium levels in the coronary arteries have greater chance of blocked arteries

A diet rich in milk does not increase the risk of heart disease and stroke

New cholesterol drug Crestor causes safety concerns

Metabolic syndrome prevalent in heart attack patients

Within six months, one in three patients fail to take cardiovascular risk-lowering medications as prescribed

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Chest CT can be first step to identifying if patient has had a heart attack

Cystatin-C, a new blood test for kidney function, is a better predictor of death and cardiovascular risk among the elderly

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