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FDA approves first adjuvant treatment for patients with non-small cell lung cancer

Today, the U.S. Food and Drug Administration approved Tagrisso (osimertinib) as the first adjuvant treatment for patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation.

18 Dec 2020

Study may help explain how COVID-19 increases stroke risk

A UCLA-led study may help explain how COVID-19 increases the risk for stroke. Scientists made the finding by running fluid spiked with a COVID-19-like protein through a 3D-printed model of the arteries of a patient who had suffered a stroke.

18 Dec 2020

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

There is light at the end of the COVID-19 pandemic tunnel. Several vaccines against the SARS-CoV-2 virus that causes COVID-19 are now in clinical trials, with one -- developed by Pfizer/BioNTech -- already having been approved for emergency use in the United States.

18 Dec 2020

Anti-hypertension drug may be key to extending lifespan, shows study

A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life.

18 Dec 2020

A protein plays key role in the spread of stress signals among liver cells

A key protein in the communication channels between cells can allow a stress response in one liver cell to spread to neighboring liver cells in mice, causing otherwise healthy cells to become dysfunctional, according to new research co-led by Harvard T.H. Chan School of Public Health and Sheba Medical Center in Israel.

18 Dec 2020

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

A new study describes the in vitro mechanism by which remdesivir kinetically inhibits the replication of the virus that causes COVID-19, SARS-CoV-2.

18 Dec 2020

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

A new paper describes the development and validation of a rapid test to measure the neutralizing activity of serum against COVID-19 using a drop of blood.

18 Dec 2020

Abbott gets CE Mark for new quantitative SARS-CoV-2 IgG lab-based serology test

Abbott announced today it received CE Mark for its new quantitative SARS-CoV-2 IgG (Immunoglobulin G) lab-based serology test.

18 Dec 2020

FDA approves pembrolizumab as first-line treatment for colorectal cancer

The FDA recently approved the immunotherapy drug pembrolizumab as a first-line treatment for patients with certain types of advanced colorectal cancer. This is the 9th FDA approval supported by Stand Up To Cancer® (SU2C) research.

18 Dec 2020

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Two new papers examine the processes of lung scarring and chronic rejection of the organ after transplantation, and potential therapies to stop the graft, or transplanted organ and its tissue, from failing.

17 Dec 2020

Research shows that people affected with COVID-19 suffer from cognitive effects

More and more evidence is coming out that people with COVID-19 are suffering from cognitive effects, such as brain fog and fatigue.

17 Dec 2020

Antifungal drug improves key biomarkers in the noses of patients with cystic fibrosis

A drug widely used to treat fungal infections improved key biomarkers in lung tissue cultures as well as in the noses of patients with cystic fibrosis, a clinical study by researchers at the University of Illinois Urbana-Champaign and the University of Iowa found.

17 Dec 2020

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

17 Dec 2020

Discovery of protein function could be important for future chemotherapy treatment

Chemotherapy attacks all cells in our body and not just cancer cells, which is why patients undergoing the treatment often experience side effects such as physical weakness, hair loss and nausea.

17 Dec 2020

Scientists develop an enhanced version of phototoxic protein

Scientists from Skoltech, the Institute of Bioorganic Chemistry of RAS, and the London Institute of Medical Sciences (LMS) have developed an enhanced version of SuperNova, a genetically encoded phototoxic synthesizer, that helps control intracellular processes by light exposure.

17 Dec 2020

MFCR awards new grants to support an emerging approach to cancer therapeutics

The Mark Foundation for Cancer Research has awarded five new grants in support of an important, emerging approach to cancer therapeutics.

17 Dec 2020

A protein may be responsible for triggering lung scarring in scleroderma patients

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

17 Dec 2020

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

Female COVID-19 patients face less severe disease complications and a lower risk of dying than male patients thanks to hormones and chromosomes that contribute to a stronger immune response, according to new research from a University of Alberta-led team.

17 Dec 2020

WEHI researchers suggest potential new approach to treat stomach cancer

WEHI researchers have identified a key molecular regulator involved in the progression and spread of stomach cancer, suggesting a potential new approach to treat this devastating disease.

17 Dec 2020

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

A preprint indicates that SARS-CoV-2 requires cholesterol to accomplish entry into the host cells and membrane fusion.

17 Dec 2020

Protein C News and Research

FDA approves first adjuvant treatment for patients with non-small cell lung cancer

Study may help explain how COVID-19 increases stroke risk

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

Anti-hypertension drug may be key to extending lifespan, shows study

A protein plays key role in the spread of stress signals among liver cells

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

Abbott gets CE Mark for new quantitative SARS-CoV-2 IgG lab-based serology test

FDA approves pembrolizumab as first-line treatment for colorectal cancer

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Research shows that people affected with COVID-19 suffer from cognitive effects

Antifungal drug improves key biomarkers in the noses of patients with cystic fibrosis

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

Discovery of protein function could be important for future chemotherapy treatment

Scientists develop an enhanced version of phototoxic protein

MFCR awards new grants to support an emerging approach to cancer therapeutics

A protein may be responsible for triggering lung scarring in scleroderma patients

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

WEHI researchers suggest potential new approach to treat stomach cancer

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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