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Novel paper-clip sized device used to tackle resistant high blood pressure

Researchers at the University of Leicester and Glenfield Hospital have successfully used a novel "paper-clip" sized vascular coupling device to tackle resistant high blood pressure.

19 Sep 2013

Wearing back braces prevents need for spinal correction surgery in children with AIS

A multi-center study led by University of Iowa researchers to determine whether wearing back braces would prevent the need for spinal correction surgery in children with adolescent idiopathic scoliosis (AIS) was cut short when early results were overwhelmingly in favor of bracing.

19 Sep 2013

Omeros announces initiation of enrollment in OMS824 Phase 2 trial for schizophrenia

Omeros Corporation today announced initiation of enrollment in a Phase 2 clinical trial of OMS824, the company's phosphodiesterase 10 inhibitor. The trial will evaluate the compound's tolerability, safety, pharmacokinetics, potential interactions with concomitant antipsychotic medications, and a battery of cognitive tests in patients with stable schizophrenia.

19 Sep 2013

Decompression surgery: An effective procedure for cervical spondylotic myelopathy

In a world-first, decompression surgery has been shown to be an effective procedure to treat cervical spondylotic myelopathy - a common progressive, degenerative disease of the spine that can lead to paralysis - according to the results of a multi-centre clinical trial published today.

19 Sep 2013

Johns Hopkins establishes center to study ELSI of applying genomics to infectious disease treatment

The National Human Genome Research Institute has selected the Johns Hopkins Berman Institute of Bioethics to establish a "Center of Excellence" to study the ethical, legal and social implications of genomic research.

19 Sep 2013

Guidance for medication in bipolar depression published

Solid evidence to guide the use of antidepressants in patients with bipolar disorder is “remarkably limited,” says the International Society for Bipolar Disorders Task Force.

18 Sep 2013

GSK Returns Vercirnon Rights To Chemocentryx After Phase III Flop

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18 Sep 2013

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Results of a Pfizer-commissioned study published this month in Annals of Internal Medicine reveal that smokers with a past or present diagnosis of major depressive disorder (MDD)* taking varenicline had a significantly higher likelihood of quitting smoking (after 12 weeks and at 52 weeks) than those who were given a placebo.

18 Sep 2013

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

Boehringer Ingelheim and Eli Lilly and Company today announced they will feature five oral and 12 poster presentations for linagliptin and the investigational compound empagliflozin* at the 49th Annual Meeting of the European Association for the Study of Diabetes (EASD) which will take place in Barcelona, from 23 – 27 September. The presentations will add to the already existing body of data on safety and efficacy of these two compounds.

18 Sep 2013

Intra-articular hyaluronic acid injections safe, effective for patients with knee osteoarthritis

A new meta-analysis of 29 randomized studies involving more than 4,500 patients with knee osteoarthritis found that intra-articular hyaluronic acid injections provided significant improvement in pain and function compared to saline injections.

18 Sep 2013

NHCS researchers discover potential cure for long QT syndrome 2

The National Heart Centre Singapore research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 in patient-specific heart cells, scoring a world's first.

18 Sep 2013

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy.

18 Sep 2013

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim's volasertib

Boehringer Ingelheim Pharmaceuticals, Inc. today announced the FDA has granted Breakthrough Therapy designation to volasertib, an investigational inhibitor of polo-like kinase, being evaluated for the treatment of patients aged 65 or older with previously untreated acute myeloid leukemia, ineligible for intensive remission induction therapy.

17 Sep 2013

Regado Biosciences announces enrollment of first patient in REGULATE-PCI clinical trial

Regado Biosciences, Inc., a biopharmaceutical company focused on the discovery and development of novel, first-in-class, actively controllable antithrombotic drug systems for acute and sub-acute cardiovascular indications, today announced the enrollment of the first patient in its REGULATE-PCI clinical trial.

17 Sep 2013

Acacia Pharma initiates two pivotal Phase 3 studies of APD421 in prevention of PONV

Acacia Pharma, a pharmaceutical company specialising in the development of drugs for supportive care, announces the initiation of two pivotal Phase 3 studies of APD421 in the prevention of post-operative nausea & vomiting (PONV).

17 Sep 2013

Hospitalizations for endocarditis have declined in recent years

Hospitalizations for endocarditis, a deadly heart infection that disproportionately affects older heart patients, have declined in recent years despite recommendations for limited use of antibiotics to prevent the illness. These findings were recently published by Yale School of Medicine researchers in the Journal of the American College of Cardiology.

17 Sep 2013

Researchers identify potentially treatable subtype of pancreatic cancer

Australian researchers have identified a potentially treatable subtype of pancreatic cancer, which accounts for about 2% of new cases. This subtype expresses high levels of the HER2 gene. HER2-amplified breast and gastric cancers are currently treated with Herceptin.

17 Sep 2013

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Vanderbilt's Eskind Diabetes Clinic has been selected to examine the ability of the drug abatacept to prevent type 1 diabetes (T1D). As part of the TrialNet consortium, Vanderbilt will be one of 14 North American sites observing the effects of the drug in people at high risk to develop T1D.

17 Sep 2013

Phone support boost to COPD patients

Researchers from Australia have found that even brief phone contact from medical professionals can provide benefits to patients with chronic obstructive pulmonary disease.

16 Sep 2013

Studying Tumor Mutations Via A Network Approach

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16 Sep 2013

Efficacy News and Research

Novel paper-clip sized device used to tackle resistant high blood pressure

Wearing back braces prevents need for spinal correction surgery in children with AIS

Omeros announces initiation of enrollment in OMS824 Phase 2 trial for schizophrenia

Decompression surgery: An effective procedure for cervical spondylotic myelopathy

Johns Hopkins establishes center to study ELSI of applying genomics to infectious disease treatment

Guidance for medication in bipolar depression published

GSK Returns Vercirnon Rights To Chemocentryx After Phase III Flop

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

Intra-articular hyaluronic acid injections safe, effective for patients with knee osteoarthritis

NHCS researchers discover potential cure for long QT syndrome 2

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim's volasertib

Regado Biosciences announces enrollment of first patient in REGULATE-PCI clinical trial

Acacia Pharma initiates two pivotal Phase 3 studies of APD421 in prevention of PONV

Hospitalizations for endocarditis have declined in recent years

Researchers identify potentially treatable subtype of pancreatic cancer

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Phone support boost to COPD patients

Studying Tumor Mutations Via A Network Approach

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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