Aging News and Research

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Scientists reveal how chemotherapy causes genetic damage in healthy blood

For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues.

2 Jul 2025

Many older adults take aspirin for heart disease prevention without doctor’s advice

Around 1 in 6 older adults take aspirin as their primary method of preventing cardiovascular disease – despite stricter guidelines that no longer always call for it, a study finds.

2 Jul 2025

Republican megabill will mean higher health costs for many Americans

President Donald Trump's "One Big Beautiful Bill" cuts federal spending on Medicaid and Affordable Care Act marketplaces by about $1 trillion over a decade, according to the nonpartisan Congressional Budget Office, threatening the physical and financial health of tens of millions of Americans.

2 Jul 2025

New brain scan tool predicts aging speed and dementia risk

Any high school reunion is a sharp reminder that some people age more gracefully than others. Some enter their older years still physically spry and mentally sharp. Others start feeling frail or forgetful much earlier in life than expected.

1 Jul 2025

Brain cells can burn fat to fuel activity

While glucose, or sugar, is a well-known fuel for the brain, Weill Cornell Medicine researchers have demonstrated that electrical activity in synapses—the junctions between neurons where communication occurs—can lead to the use of lipid or fat droplets as an energy source.

1 Jul 2025

HIV treatment linked to risk of early knee osteoarthritis

Acquired immune deficiency syndrome, or AIDS, caused by the human immunodeficiency virus (HIV), weakens the body's immune system and can be life-threatening if left untreated.

1 Jul 2025

Inflammaging may be a lifestyle phenomenon rather than a universal aging trait

Inflammation, long considered a hallmark of aging, may not be a universal human experience, according to a new study from Columbia University Mailman School of Public Health.

1 Jul 2025

Study uncovers how inflammation in brain blood vessels exacerbates damage in vascular dementia

A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional recovery in mice.

1 Jul 2025

Glycogen metabolism in neurons emerges as key to fighting Alzheimer's

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

1 Jul 2025

Aging brain adapts to read ambiguous facial expressions

Because aging weakens cognitive skills, older people can struggle to read difficult social cues. A brain region involved in attention and arousal-the locus coeruleus (LC)-helps with complex tasks, and its connections to the cortex may adapt as humans age to support cognition.

30 Jun 2025

Oleic acid from olive oil reduces infection-related bone loss with age

A mouse study shows that dietary oleic acid, a key Mediterranean diet component, protects against age-related bone and microbiome damage triggered by periodontal infection. In contrast, a Western-style palmitic acid diet worsens bone loss and destabilizes the gut microbiome.

30 Jun 2025

Shingles and RSV vaccines with AS01 adjuvant reduce dementia risk

Researchers found that older adults who received AS01-adjuvanted shingles or RSV vaccines had a significantly lower risk of developing dementia within 18 months compared to flu vaccine recipients. The protective effect is likely linked to the AS01 adjuvant itself, highlighting new avenues for dementia prevention.

30 Jun 2025

Gut microbiota and metabolic changes linked to pregnancy risks in women with PCOS

A new study presented today at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) reveals that women with polycystic ovary syndrome (PCOS) have distinct gut microbiota and metabolic signatures linked to premature endometrial aging and a higher risk of adverse pregnancy outcomes.

30 Jun 2025

Comprehensive study maps genetic mutations in SLC13A5 linked to epilepsy

Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a particularly severe form of epileptic encephalopathy.

30 Jun 2025

Coffee’s hidden compounds could help fight type 2 diabetes

A comprehensive review of nearly 150 studies reveals that coffee polyphenols may help regulate blood sugar and reduce inflammation linked to type 2 diabetes. However, most evidence comes from preclinical research, and robust clinical trials are needed to confirm benefits.

29 Jun 2025

How 50,000 years of ancestry shaped India’s unique disease patterns

Scientists sequenced the genomes of 2,762 individuals across India, revealing the country’s unique ancestral makeup and a wealth of previously undocumented disease-related gene variants. The study highlights how ancient migrations, founder effects, and endogamy have shaped both diversity and disease risk in India.

29 Jun 2025

Newly discovered target may re-energize exhausted immune cells in the fight against cancer

Van Andel Institute scientists and collaborators have discovered a potential treatment target that may re-energize dysfunctional or "exhausted" immune cells in their fight against cancer.

27 Jun 2025

Blood test can reveal early signs of leukemia without bone marrow sampling

What if a blood test could reveal the pace of our aging – and the diseases that may lie ahead? The labs of Profs. Liran Shlush and Amos Tanay at the Weizmann Institute of Science have been conducting in-depth studies into the biology of blood to better understand the aging process and why some people become more susceptible to disease over the years.

27 Jun 2025

Proteome imbalance from aneuploidy linked to mitochondrial dysfunction

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances.

27 Jun 2025