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Gene therapy could be potential treatment for neuropathic pain in cancer patients

A study providing new information about neuropathic pain afflicting some 90 percent of cancer patients who have had nerve damage caused by tumors, surgery, chemotherapy or radiation indicates gene therapy as a possible treatment.

6 May 2016

Novel gene therapy can treat pulmonary hypertension linked with heart failure

Scientists have used a novel gene therapy to halt the progression of pulmonary hypertension, a form of high blood pressure in the lung blood vessels that is linked to heart failure, according to a study led by Roger J. Hajjar, MD, Professor of Medicine and Director of the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai.

30 Apr 2016

Researchers reposition existing prazosin drug to combat glioblastoma

Treatments available for glioblastoma—malignant brain tumors—have little effect. An international collaboration led by the Laboratoire Neurosciences Paris-Seine tested active ingredients from existing medications and eventually identified one compound of interest, prazosin, on these tumors. Not only did it seem to be effective in this type of cancer, but it also acted on a signaling pathway that is common with other cancers.

21 Apr 2016

NanoString launches new nCounter Vantage assays that power 3D Biology experiments in cancer research

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced the introduction of nCounter Vantage, a portfolio of assays that power 3D Biology™ experiments in cancer research, including immuno-oncology.

From NanoString Technologies 19 Apr 2016

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

A group of six newly discovered proteins may help to divulge secrets of how we age, potentially unlocking new insights into diabetes, Alzheimer's, cancer, and other aging-related diseases.

12 Apr 2016

Researchers identify vital inflammatory mechanisms in type 1 diabetes, obesity-related kidney dysfunction

In a new study, published in the online edition of the journal EBioMedicine, a multi-disciplinary team led by researchers at University of California, San Diego School of Medicine has identified key inflammatory mechanisms underlying type 1 diabetes and obesity-related kidney dysfunction.

11 Apr 2016

Versatile Automated Microplate Sample Screening Applications

In this interview, News Medical speaks Tobias Pusterla, Ph.D from BMG Labtech about versatile automated microplate sample screening applications.

From BMG LABTECH GmbH 30 Mar 2016

Study reveals how lipids control SH2 domain-mediated cellular protein interactions

Prof. You-Me Kim and her student Dajung Jung at Pohang University of Science and Technology, in collaboration with Prof. Wonhwa Cho's group at the University of Illinois at Chicago, have identified that the majority of human Src homology 2 (SH2) domains not only bind to proteins, but also interact with membrane lipids with high affinity and specificity.

29 Mar 2016

Lack of ARHGAP33 molecule causes neuropsychiatric disorders-related abnormal higher brain functions

A research group led by Osaka University and the University of Tokyo found that the intracellular protein trafficking is important for higher brain functions such as learning and memory. The research group showed that a molecule, ARHGAP33 regulates synaptic functions and behaviors via intracellular protein trafficking and that the lack of ARHGAP33 causes neuropsychiatric disorder-related impaired higher brain functions.

29 Mar 2016

FEI, NovAliX to jointly provide cryo-EM-based structural analysis services for pharmaceutical and biotech industry

FEI and NovAliX, a contract research organization (CRO), announced today a strategic partnership to enable NovAliX to provide commercial cryo-electron microscopy (EM)-based structural analysis services to its customers in the pharmaceutical and biotech industry.

From Thermo Fisher Scientific – Electron Microscopy Solutions 23 Mar 2016

ORNL-NIST researchers reveal nondestructive way to observe nanoscale objects and processes

When lots of energy hits an atom, it can knock off electrons, making the atom extremely chemically reactive and initiating further destruction. That's why radiation is so dangerous. It's also why high-resolution imaging techniques that use energetic electron beams and X-rays can alter, even obliterate, the samples they explore. For example, monitoring battery dynamics using electron microscopy can introduce artifacts that interfere with electrochemical processes.

22 Mar 2016

Cell biologists identify new way for curing cancer and vessel diseases

Cell biologists from the Lomonosov Moscow State University discovered a new way of regulating of cell motility -- this discovery will make possible development of new drugs for curing onco- and vessel diseases.

22 Mar 2016

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Head and neck cancers (HNC) are the sixth most common cancers worldwide, with approximately 600,000 new cases diagnosed every year.

From Beckman Coulter Life Sciences - Centrifugation 17 Mar 2016

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

A series of cell-based tests developed to compare the biological impact of cigarette smoke with e-cigarette vapour revealed no activity in cells exposed to vapour from Vype ePen, a commercially available e-cigarette.

16 Mar 2016

Study could lead to potential new therapeutic target with fewer side effects for hypertension

A team of Vermont investigators has been issued a patent for their discovery of a molecule that rescues damaged blood vessels, yet preserves healthy vessels and could serve as a springboard for a new pharmaceutical therapy with fewer side effects for hypertension - a major risk factor for cardiovascular and kidney disease that effects roughly one in three people in the U.S.

15 Mar 2016

Discovery may provide potential target for new therapies to treat bipolar disorder

Bipolar disorder, which affects nearly eight million Americans, takes a toll not only on patients, but also on their families and communities.

10 Mar 2016

Blueberry Therapeutics set to create safe, effective nanomedicines to tackle unmet healthcare needs

Blueberry Therapeutics Ltd, a leading pharmaceutical company focused on the major medical problems of inflammation and infection, are exploring the anti-microbial agenda through the development of new anti-fungal drugs and treatments to tackle this important unmet healthcare need.

2 Mar 2016

"Neoehrlichiosis" Internationally Diagnosed And Successfully Treated In Patients Without Immunodeficiency For The First Time

The intercellular bacteria "Candidatus Neoehrlichia", as e.g. Borrelia, can be transferred by ticks. Approx. 4.2 % of indigenous ticks are infected with this rarely explored bacterium which, until today, has been exclusively identified as pathogenic bacterium in patients with an impairment of the immune system, such as in case of leukaemia, rheumatism or after organ transplantation.

1 Mar 2016

Intracellular process of autophagy plays role in prostate cancer development, shows research

Research from investigators at Rutgers Cancer Institute of New Jersey and the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, shows the intracellular process of autophagy plays a role in the development of prostate cancer.

15 Feb 2016

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research.

9 Feb 2016