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Personalized medicine approaches for sepsis based on immune response profiling

Sepsis patients could be treated based on their immune system's response to infection, not their symptoms.

18 Jun 2024

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

In a study with 991 adults, scientists at DZNE show that the most common forms of frontotemporal dementia (FTD) as well as the neurological diseases amyotrophic lateral sclerosis (ALS) and progressive supranuclear palsy (PSP) can be recognized by blood testing.

18 Jun 2024

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

Older women are different than older men. Their health is woefully understudied.

Medical research has shortchanged women for decades. This is particularly true of older women, leaving physicians without critically important information about how to best manage their health.

18 Jun 2024

Researchers develop cutting-edge smart bandages for improved wound healing

Chronic wounds, which include diabetic ulcers, surgical wounds, pressure injuries, and other problems, are deadlier than many people realize.

17 Jun 2024

Newly designed genetic therapy could alleviate debilitating giant moles in rare skin condition

Researchers at the Francis Crick Institute, UCL Great Ormond Street Institute for Child Health and Great Ormond Street Hospital for Children (GOSH) have designed a new genetic therapy that could alleviate debilitating giant moles in a rare skin condition.

17 Jun 2024

HEALing Communities Study: Data-driven intervention did not reduce opioid-related overdose death rates

A data-driven intervention that engaged communities to rapidly deploy evidence-based practices to reduce opioid-related overdose deaths – such as increasing naloxone distribution and enhancing access to medication for opioid use disorder – did not result in a statistically significant reduction in opioid-related overdose death rates during the evaluation period, according to results from the National Institutes of Health's HEALing (Helping to End Addiction Long-Term) Communities Study.

17 Jun 2024

New open-access resource reveals nutrient content of Indian foods

Scientists developed an open-access Indian Nutrient Databank with nutrient compositions of raw food items and commonly consumed recipes.

16 Jun 2024

Global study confirms pantoprazole's role in reducing upper GI bleeding in the ICU

A widely available drug helps prevent upper gastrointestinal bleeding in critically ill adults on a breathing machine, according to the results of a global study and meta-analysis led by researchers at McMaster University.

14 Jun 2024

Mutated TREX1 gene linked to catastrophic DNA damage and deadly rare disease

TREX1 is a gene that is supposed to direct the maintenance of the entire body's DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a deadly rare disease called retinal vasculopathy with cerebral leukoencephalopathy (RVCL).

13 Jun 2024

Study reveals why EGFR inhibitors fail in some non-smokers with lung cancer

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

13 Jun 2024

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

13 Jun 2024

Replacing TV time with light activity or sleep boosts healthy aging odds

Sedentary behavior reduces the odds of healthy aging, while light physical activity increases them. Replacing TV time with light activity, exercise, or sleep improves healthy aging odds.

13 Jun 2024

Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

New robot system used to improve treatment for debilitating eye disease

Researchers from King's, with doctors at King's College Hospital NHS Foundation Trust, have successfully used a new robot system to improve treatment for debilitating eye disease.

11 Jun 2024

Study reveals unconscious fear of exercise in knee osteoarthritis patients

Knee osteoarthritis (OA) is a common cause of pain and joint stiffness. And while physical activity is known to ease symptoms, only one in 10 people regularly exercise.

11 Jun 2024

Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius - nearly twice as cold as the coldest places in Antarctica - scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

10 Jun 2024

Multiple general anesthesia exposure does not compromise brain function in young children, study finds

A University of Queensland-led study has found multiple doses of anesthetics do not compromise brain function in young children.

10 Jun 2024

Doxycycline shows promise in reducing deaths and seizures from nodding syndrome

A new study suggests that a course of the drug doxycycline can decrease acute seizure-related hospitalization and deaths related to nodding syndrome.

8 Jun 2024

Medical Research News and Research

Personalized medicine approaches for sepsis based on immune response profiling

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

Older women are different than older men. Their health is woefully understudied.

Researchers develop cutting-edge smart bandages for improved wound healing

Newly designed genetic therapy could alleviate debilitating giant moles in rare skin condition

HEALing Communities Study: Data-driven intervention did not reduce opioid-related overdose death rates

New open-access resource reveals nutrient content of Indian foods

Global study confirms pantoprazole's role in reducing upper GI bleeding in the ICU

Mutated TREX1 gene linked to catastrophic DNA damage and deadly rare disease

Study reveals why EGFR inhibitors fail in some non-smokers with lung cancer

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

Replacing TV time with light activity or sleep boosts healthy aging odds

Changing antibiotic delivery method improves sepsis outcomes globally

New robot system used to improve treatment for debilitating eye disease

Study reveals unconscious fear of exercise in knee osteoarthritis patients

Understanding Crohn's disease through 'mini-gut' models

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

Multiple general anesthesia exposure does not compromise brain function in young children, study finds

Doxycycline shows promise in reducing deaths and seizures from nodding syndrome

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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