Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Novel proteomics based method detects inhibition of intracellular deubiquitylating enzymes

Researchers at the University of Oxford and Progenra, Inc. are pleased to announce the publication of a research article entitled "Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes" that details a novel proteomics based method to detect inhibition of intracellular deubiquitylating enzymes (DUBs).

28 Nov 2011

VHIO, MGHCC sign tumor biomarker agreement

The President of the BBVA Foundation, Francisco Gonz-lez, Jose Baselga, Chief of Hematology/Oncology at Massachusetts General Hospital Cancer Center (MGHCC), and Andr-s de Kelety, Managing Director at the Vall d'Hebr-n Institute of Oncology (VHIO) in Barcelona, yesterday signed the agreement creating the BBVA Foundation Tumor Biomarkers Research Program.

17 Nov 2011

Women with inflammatory breast cancer now have a chance of treatment

Women with the deadliest and rarest form of breast cancer now have a chance of treatment where once their options were severely limited, thanks to a new discovery by George Mason University researchers.

15 Nov 2011

Amplification of ALK gene may drive rapid breast cancer metastasis

Amplification of anaplastic lymphoma kinase, which has been reported in other cancers such as non-small cell lung cancers, may be a primary driver of the rapid metastasis that patients with inflammatory breast cancer experience.

14 Nov 2011

Pall launches new Acrodisc MS syringe filter

Pall Corporation, today introduced the Pall Acrodisc MS Syringe Filter the first syringe filter certified for low extractables in high performance liquid chromatography/mass spectrometry (LCMS) applications.

From Pall Corporation 5 Nov 2011

NIH-funded project to discover biomarkers for type 2 diabetes

Arizona State University will lead a four-year, $5 million expanded initiative sponsored by the National Institutes of Health to discover proteins, or biomarkers, to help predict cardiovascular disease and to assess potential new treatments in people with type 2 diabetes.

2 Nov 2011

New protein microarray technology could eradicate malaria

A new research technology is revealing how humans develop immunity to malaria, and could assist programs aimed at eradicating this parasitic disease.

2 Nov 2011

New top-down method can quickly separate, identify thousands of protein molecules

A team led by Northwestern University chemical biologist Neil Kelleher has developed a new "top-down" method that can separate and identify thousands of protein molecules quickly. Many have been skeptical that such an approach, where each protein is analyzed intact instead of in smaller parts, could be done on such a large scale.

31 Oct 2011

Pall, NIBRT co-host master class on single-use systems in manufacturing of biopharmaceuticals

Pall Life Sciences and the National Institute for Bioprocessing Research and Training (NIBRT) in Ireland recently co-hosted a master class on the use of single-use systems in the development and manufacturing of biopharmaceuticals.

From Pall Corporation 29 Oct 2011

NIH awards DNASU $6.5M grant to expand Protein Structure Initiative-Materials Repository

Arizona State University's Biodesign Institute- is home to a rich trove of biological material. Known as DNASU, this growing storehouse-a sort of genetic Library of Congress-holds over 147,000 plasmids, (circular DNA samples that can be used to produce individual proteins), as well as full genome collections from numerous organisms and proteins associated with many leading human diseases.

21 Oct 2011

Agilent announces winners of 2011 eMerging Insights grant program

Agilent Technologies Inc. today announced the winners of the 2011 eMerging Insights grant program: Dr. Michael J. MacCoss of the University of Washington and Dr. Peter J. Park of Harvard University. Each will be awarded $75,000 toward their ongoing research on open source data-integration tools.

21 Oct 2011

SomaLogic, Novartis enter multi-year research agreement

SomaLogic, Inc., announced today that it has entered into a multi-year research agreement with Novartis to use its unique proprietary proteomics technology to accelerate Novartis' drug discovery and development efforts.

19 Oct 2011

UA researchers to study immune response to implanted sensors

A University of Arkansas professor and her colleagues will receive $1.3 million over four years to study the immune response to implanted sensors, such as glucose sensors for diabetics, in hopes of prolonging the life of these important monitoring systems.

13 Oct 2011

USPTO issues patent to Oragenics' In Vivo Induced Antigen Technology

Florida-based nutraceutical company, Oragenics, Inc., announced today the issuance of patent number 8,034,571 from the United States Patent and Trademark office for In Vivo Induced Antigen Technology.

13 Oct 2011

New process makes linear peptides circular

Peptides and proteins have long been an attractive class of drug candidates because of their natural involvement in cellular processes and fewer potential side effects. Dr. Andrei Yudin, Professor, Department of Chemistry, University of Toronto, has developed a new and effective process that makes linear peptides circular, which allows these molecules, called macrocycles, to enter cells more effectively and increase their stability compared to linear peptides.

29 Sep 2011

Applied Biomics adds iTRAQ service to its proteomics line

Applied Biomics, Inc., a leading Proteomics service provider, is pleased to announce the addition of iTRAQ service (Isobaric Tags for Relative and Absolute Quantitation) to its proteomics line.

28 Sep 2011

Biotica, Buck Institute collaborate to investigate polyketides in diseases of aging

The Buck Institute for Research on Aging and Biotica Technology Ltd. today announced a three-year collaboration to investigate polyketides in diseases of aging. Building on observations that rapamycin extends healthy lifespan in various species, the collaborators will evaluate rapamycin analogs and other polyketides in a broad range of age-related disease models to identify novel therapeutics.

14 Sep 2011

BGI, Merck collaborate to focus on biomarkers and genomic technologies

Merck, known as MSD outside the United States and Canada, and BGI, the world's largest genomics center, announced today that they have established a collaboration to focus on the discovery and development of biomarkers and genomic technologies.

13 Sep 2011

Huge economic, social and personal burden of AF-related strokes across Latin America

Urgent coordinated action from national governments, medical societies and patient organizations is needed to avoid a public health crisis resulting from the tide of preventable strokes that leave many people with atrial fibrillation (AF) mentally and physically disabled or dead, every year. How Can We Avoid a Stroke Crisis in Latin America?, a report from Action for Stroke Prevention - a group of health experts from around the world - reveals the huge economic, social and personal burden of AF-related strokes across the region.

12 Sep 2011

LC-MRM could provide better understanding of multiple myeloma drug resistance

"Acquired drug resistance" (ADR) is a major problem encountered in treating some forms of cancer. The ability to monitor the proteins involved in drug resistance has been a hurdle facing cancer researchers.

12 Sep 2011