Immune System News and Research

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New insight provides potential to improve treatment for sepsis

In a review published in the April issue of Immunity, Kevin J. Tracey, MD, president of The Feinstein Institute for Medical Research, says it's time to take a fresh look at the medical community's approach to treating sepsis, which kills millions worldwide every year, including more than 200,000 Americans.

18 Apr 2014

Researchers identify novel vancomycin-resistant MRSA superbug in Brazil

An international research team led by Cesar A. Arias, M.D., Ph.D., at The University of Texas Health Science Center at Houston has identified a new superbug that caused a bloodstream infection in a Brazilian patient. The report appeared in the April 17 issue of The New England Journal of Medicine.

17 Apr 2014

SWHR co-sponsors National Institutes of Health Forum on microbiome and autoimmunity

The Society for Women's Health Research (SWHR®), the leading voice on the study of the biological differences between women and men, is co-sponsoring the National Institutes of Health (NIH) Forum on the Microbiome and Autoimmunity on Thursday, April 24, at the NIH in Bethesda, Md.

17 Apr 2014

Researchers uncover mechanism that may help explain severe forms of schistosomiasis

Researchers at the Sackler School of Graduate Biomedical Sciences at Tufts and Tufts University School of Medicine (TUSM) have uncovered a mechanism that may help explain the severe forms of schistosomiasis, or snail fever, which is caused by schistosome worms and is one of the most prevalent parasitic diseases in the world. The study in mice, published online in The Journal of Immunology, may also offer targets for intervention and amelioration of the disease.

17 Apr 2014

Scientists discover protein structure that helps common fungal pathogen to infect humans

A team that includes scientists from the School of Medicine at The University of Texas Health Science Center at San Antonio, Johns Hopkins University and St. Mary's University reported the structure of a protein that helps a common fungus to infect the body.

17 Apr 2014

Researchers develop class of drugs to lessen impact of Alzheimer's, Parkinson's

A class of drugs developed to treat immune-related conditions and cancer - including one currently in clinical trials for glioblastoma and other tumors - eliminates neural inflammation associated with dementia-linked diseases and brain injuries, according to UC Irvine researchers.

17 Apr 2014

Study: HIV-positive women respond well to vaccine against human papillomavirus

HIV-positive women respond well to a vaccine against the human papillomavirus (HPV), even when their immune system is struggling, according to newly published results of an international clinical trial.

17 Apr 2014

Freiburg researchers discover molecule that smuggles toxins from intestinal pathogens into human cells

Prof. Dr. Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the Institute of Experimental and Clinical Pharmacology and Toxicology of the University of Freiburg have discovered the receptor responsible for smuggling the toxin of the bacterium Clostridium perfringens into the cell.

17 Apr 2014

Iconic Therapeutics completes $20 million Series B-1 equity financing

Iconic Therapeutics, Inc., a biotechnology company focused on developing therapeutics for serious eye disorders, announced today that it has successfully completed a $20 million Series B-1 equity financing from new investors MPM Capital, Lundbeckfond Ventures, and H.I.G. BioVentures.

16 Apr 2014

Understanding GPCRs and controlling inflammation: an interview with Dr. Richard Proia, NIDDK, NIH

GPCRs are one of the largest families of cellular signalling proteins consisting of more than a thousand different types. They reside on the surface membranes of cells where they are poised to recognize molecules in the exterior environment and then transmit this information through the membrane allowing cells to respond accordingly.

16 Apr 2014

Study: Bacterium that causes whooping cough changes in Australia

The bacterium that causes whooping cough, Bordetella pertussis, has changed in Australia - most likely in response to the vaccine used to prevent the disease - with a possible reduced effectiveness of the vaccine as a result, a new study shows.

16 Apr 2014

Dental researchers find new way to study how mouth's natural defenses ward off infection, inflammation

Case Western Reserve University dental researchers have found a less invasive way to extract single rare immune cells from the mouth to study how the mouth's natural defenses ward off infection and inflammation.

16 Apr 2014

Researchers identify mechanism that explains reason for persistence of hepatitis C virus

Researchers at the University of California, San Diego School of Medicine have identified a mechanism that explains why people with the hepatitis C virus get liver disease and why the virus is able to persist in the body for so long.

16 Apr 2014

Study sheds light on factors that lead to development of rare condition affecting inner ear

A new study has shed light on the factors likely to lead to the development of a rare condition affecting the inner ear.

16 Apr 2014

Optimal use of combination therapy achieves best treatment outcomes in patients with CHB

Three new studies presented today at the International Liver CongressTM 2014 have helped clarify the optimal use of combination therapy with peginterferon and nucleoside analogues (NUCs) to achieve the best treatment outcomes in patients with chronic hepatitis B (CHB).

16 Apr 2014

Pitt CVR and Sanofi Pasteur join forces to help assess effectiveness of dengue vaccine

The University of Pittsburgh Center for Vaccine Research (CVR) and Sanofi Pasteur, the vaccines division of Sanofi, have entered a scientific collaboration to help assess the effectiveness of a dengue vaccine once introduced for immunization programs.

16 Apr 2014

EventusDx completes $2.72M financing to support development, commercialization of Octava breast cancer tests

Eventus Diagnostics, Inc. today announced completion of a $2.72 million financing. The financing was led by a new family office private investor, and existing investors also participated. Proceeds of the financing will mostly be used to support the continued development and commercialization of the company's Octava breast cancer tests.

15 Apr 2014

Kineta, RLB Holdings form joint venture to address unmet medical needs

Kineta, Inc., a biotechnology company focused on the development of immune-modulating drugs for critical diseases, and RLB Holdings, an investment fund founded by Ray and Lydia Bartoszek, have formed a joint venture, Kineta RLB, LLC, which will commercialize promising, high-value compounds in selective disease areas with unmet medical needs.

15 Apr 2014

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

A phase III clinical trial conducted at the Meir Medical Center in Kfar-Saba, Israel is now recruiting participants to study the effects of dietary supplement PectaSol-C modified citrus pectin (MCP) in controlling prostate specific antigen (PSA) levels in prostate cancer patients.

15 Apr 2014

Study shows how infection worsens damage caused by stroke

Infection is bad news for all of us - but it can be really serious to people who have had a stroke. Evidence is mounting that infection makes things much worse after a stroke.

15 Apr 2014

Immune System News and Research

New insight provides potential to improve treatment for sepsis

Researchers identify novel vancomycin-resistant MRSA superbug in Brazil

SWHR co-sponsors National Institutes of Health Forum on microbiome and autoimmunity

Researchers uncover mechanism that may help explain severe forms of schistosomiasis

Scientists discover protein structure that helps common fungal pathogen to infect humans

Researchers develop class of drugs to lessen impact of Alzheimer's, Parkinson's

Study: HIV-positive women respond well to vaccine against human papillomavirus

Freiburg researchers discover molecule that smuggles toxins from intestinal pathogens into human cells

Iconic Therapeutics completes $20 million Series B-1 equity financing

Understanding GPCRs and controlling inflammation: an interview with Dr. Richard Proia, NIDDK, NIH

Study: Bacterium that causes whooping cough changes in Australia

Dental researchers find new way to study how mouth's natural defenses ward off infection, inflammation

Researchers identify mechanism that explains reason for persistence of hepatitis C virus

Study sheds light on factors that lead to development of rare condition affecting inner ear

Optimal use of combination therapy achieves best treatment outcomes in patients with CHB

Pitt CVR and Sanofi Pasteur join forces to help assess effectiveness of dengue vaccine

EventusDx completes $2.72M financing to support development, commercialization of Octava breast cancer tests

Kineta, RLB Holdings form joint venture to address unmet medical needs

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

Study shows how infection worsens damage caused by stroke

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