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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Scientists discover rare genetic alteration responsible for hypoglycaemia

Cambridge scientists have identified the cause of a rare, life-threatening form of hypoglycaemia. Their findings, which have the potential to lead to pharmaceutical treatments for the disorder, were published today, 07 October, in the journal Science.

7 Oct 2011

Teriflunomide drug reduces relapse rate of people with MS

A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease.

7 Oct 2011

Thriving stem cells created by cloning technique

In a breakthrough that has been debated and awaited for long, scientists have finally derived colonies of embryonic stem cells from human embryos created using cloning technology.

6 Oct 2011

Illumina, UNTHSC enter next-generation sequencing collaboration in forensic DNA analysis

Illumina, Inc. today announced it has entered into a wide-ranging collaborative research agreement with the Institute of Applied Genetics and the Department of Forensic and Investigative Genetics at the University of North Texas Health Science Center (UNTHSC). Illumina and UNTHSC will collaborate on several visionary projects in forensics using Illumina's next-generation sequencing technologies.

From Illumina, Inc. 4 Oct 2011

Virus DNA uncoated with aid of host cell

They have been around since the dawn of time and are a model of evolutionary success: viruses. Viruses are extremely adaptable but they have a problem: They cannot reproduce, so they smuggle their genes into suitable host cells. In the case of some viruses, the viral DNA has to enter the cell nucleus to reproduce. This has been known for almost 50 years.

4 Oct 2011

Sequenom launches iPLEX ADME PGx panel to genotype polymorphisms

Sequenom, Inc., a life sciences company providing innovative genetic analysis solutions, today announced the launch of its iPLEX ADME PGx panel developed to genotype polymorphisms in genes associated with drug absorption, distribution, metabolism, and excretion (ADME).

4 Oct 2011

CRT, Cancer Research UK establish group of scientists with expertise in lipid metabolism

Cancer Research Technology, Cancer Research UK's commercial arm, has established a group of scientists with expertise in lipid metabolism - getting energy from fats and making building blocks for cell growth - to develop targets for potential new cancer drugs.

4 Oct 2011

Life Technologies, CHEO researcher partner to co-develop microbial detection tests

The Children's Hospital of Eastern Ontario (CHEO) Research Institute is pleased to announce that one of its principal investigators in infectious disease has signed a contract with Life Technologies, an internationally renowned biotech tools company headquartered in Carlsbad, California, to share information that will help to develop tests that uniquely amplify and detect the DNA coding for infectious diseases.

4 Oct 2011

DNA primer vaccine enhances immune response to H5N1 avian influenza vaccine

The immune response to an H5N1 avian influenza vaccine was greatly enhanced in healthy adults if they were first primed with a DNA vaccine expressing a gene for a key H5N1 protein, researchers say.

4 Oct 2011

Complete Genomics, Scripps collaborate to unlock genetic secrets of lifelong health

Complete Genomics Inc., the whole human genome sequencing company, and the not-for-profit Scripps Health system today announced a major collaboration that will help further the Wellderly Study, a landmark scientific research initiative aimed at unlocking the genetic secrets of lifelong health.

4 Oct 2011

Novel drug shows promise for MLL leukemia

According to British scientists a potential new drug from GlaxoSmithKline could treat mixed-lineage leukemia (MLL). MLL is the most common form of leukemia in babies. The study appeared in the journal Nature where scientists from the British drugmaker collaborating with the charity Cancer Research UK (CRUK) and Cellzome AG found that the experimental drug, called I-BET151.

3 Oct 2011

Sangamo's SB-509 fails to meet key endpoints in Phase 2b study for diabetic neuropathy

Sangamo BioSciences, Inc. today announced that its Phase 2b study (SB-509-901) did not meet its primary or secondary clinical endpoints in subjects with moderate severity diabetic neuropathy (DN) as compared to placebo.

3 Oct 2011

Potential new drug could treat mixed-lineage leukaemia

A team lead by Cancer Research UK scientists have shown that a potential new drug could treat mixed-lineage leukaemia (MLL), the most common form of leukaemia in babies, according to a study published in Nature today.

3 Oct 2011

GeoVax completes enrollment for HIV/AIDS vaccine Phase 2a clinical trial

GeoVax Labs, Inc., an Atlanta-based biopharmaceutical firm developing vaccines to prevent and fight Human Immunodeficiency Virus (HIV) infections, announced today the completion of enrollment for a Phase 2a clinical trial testing its HIV/AIDS vaccine.

3 Oct 2011

Researchers identify unusual genomic architecture linked with very severe forms of disease

When cells divide normally, DNA gets copied perfectly and distributed among the daughter cells with an even hand. Occasionally though, DNA breaks during division and is rearranged, resulting in duplications or deletions of important parts of the blueprint.

3 Oct 2011

Scientists discover 16 million SNPs that associate with increased risk of ovarian cancer

Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain and Finland today report the discovery of variants in the human genome that associate with increased risk of invasive ovarian cancer, one of the deadliest forms of cancer in women.

3 Oct 2011

Combination of P16 immunohistochemistry, DNA qPCR can accurately detect oropharyngeal cancer

Researchers have determined that a combination of P16 immunohistochemistry and DNA qPCR to test for viral E6 can accurately determine the oropharyngeal squamous cell carcinoma, a form of head and neck cancer, which derive from HPV16, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

3 Oct 2011

WSU to help develop alternatives to petroleum-based fuels and chemicals

U.S. Department of Agriculture Secretary Tom Vilsack yesterday announced that Washington State University (WSU) will receive a five-year, $40 million grant to help develop alternatives to petroleum-based fuels and chemicals.

3 Oct 2011

Researchers identify gene responsible for starting the biological clock

Ever wondered why you wake up in the morning ---- even when the alarm clock isn't making jarring noises? Wonder no more. Researchers at the Salk Institute for Biological Studies have identified a new component of the biological clock, a gene responsible for starting the clock from its restful state every morning.

1 Oct 2011

Scientists discover that DNA modifications in brain cells change due to stimulated brain activity

Johns Hopkins scientists investigating chemical modifications across the genomes of adult mice have discovered that DNA modifications in non-dividing brain cells, thought to be inherently stable, instead underwent large-scale dynamic changes as a result of stimulated brain activity.

1 Oct 2011

DNA News and Research

Further Reading

Scientists discover rare genetic alteration responsible for hypoglycaemia

Teriflunomide drug reduces relapse rate of people with MS

Thriving stem cells created by cloning technique

Illumina, UNTHSC enter next-generation sequencing collaboration in forensic DNA analysis

Virus DNA uncoated with aid of host cell

Sequenom launches iPLEX ADME PGx panel to genotype polymorphisms

CRT, Cancer Research UK establish group of scientists with expertise in lipid metabolism

Life Technologies, CHEO researcher partner to co-develop microbial detection tests

DNA primer vaccine enhances immune response to H5N1 avian influenza vaccine

Complete Genomics, Scripps collaborate to unlock genetic secrets of lifelong health

Novel drug shows promise for MLL leukemia

Sangamo's SB-509 fails to meet key endpoints in Phase 2b study for diabetic neuropathy

Potential new drug could treat mixed-lineage leukaemia

GeoVax completes enrollment for HIV/AIDS vaccine Phase 2a clinical trial

Researchers identify unusual genomic architecture linked with very severe forms of disease

Scientists discover 16 million SNPs that associate with increased risk of ovarian cancer

Combination of P16 immunohistochemistry, DNA qPCR can accurately detect oropharyngeal cancer

WSU to help develop alternatives to petroleum-based fuels and chemicals

Researchers identify gene responsible for starting the biological clock

Scientists discover that DNA modifications in brain cells change due to stimulated brain activity

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