Enzyme News and Research

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Stress affects molecules believed to play a key role in cellular aging

There have been many studies that have shown that your health is greatly affected by how you react to stressful events in life-setbacks or deadlines at work, conflicts and losses at home.

29 Nov 2004

Salmonella pathogen uses molecular hydrogen to grow and become virulent

New research, headed by microbiologists from the University of Georgia, show for the first time that Salmonella – a widespread and often deadly bacterial pathogen – use molecular hydrogen to grow and become virulent.

29 Nov 2004

Nanoscale switch could serve as sensor, medical tool

Improving significantly on an early prototype, Johns Hopkins University researchers have found a new way to join two unrelated proteins to create a molecular switch, a nanoscale "device" in which one biochemical partner controls the activity of the other.

29 Nov 2004

Researchers have discovered that by blocking a specific enzyme, it is possible to check the spread of cancer

A team of Danish researchers have discovered that by blocking a specific enzyme, it is possible to check the spread of cancer in the body. This finding may be the first step towards preventing deaths due to cancer spreading to other parts of the body.

23 Nov 2004

Acid-resistant bug also alcohol-resistant

A chemist at Washington University in St. Louis has found surprisingly tough enzymes in a bacterium that "just says no to acid."

23 Nov 2004

New findings have implications for chronic use of COX-2 Inhibitors in pre-menopausal women

Heart disease is less pronounced in women than in men as humans age, but this difference narrows after menopause. Some studies have shown that estrogen slows heart disease in mouse models, but the mechanism is largely unknown.

18 Nov 2004

Patented fibrin-based matrices and tissue may open doors for tissue and organ engineering

Virginia Commonwealth University engineers and scientists have developed and patented a unique technique to grow three-dimensional tissues and organs in a mold made from material the human body naturally uses to repair wounds, potentially eliminating the chance for rejection.

17 Nov 2004

Startling new blood pressure findings - atherosclerosis slowed

A new study led by The Cleveland Clinic shows that giving blood pressure lowering medication to heart disease patients with a “normal” blood pressure dramatically reduces risk of adverse cardiac events and slows disease progression.

16 Nov 2004

Novel enzyme in sperm is essential for spontaneous and independent movement

A study led by scientists at the University of North Carolina at Chapel Hill has found that a novel enzyme in sperm is essential for spontaneous and independent sperm movement as well as male fertility.

16 Nov 2004

Breast cancer study seeks postmenopausal women

Researchers at RMIT University's Department of Food Science are recruiting healthy, postmenopausal women to volunteer for a study to see if diet and lifestyle can improve the treatment of breast cancer.

16 Nov 2004

Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Scientists at Johns Hopkins and the University of Texas Medical Branch have created a new tool that easily reveals when and where a key cellular signal is active.

16 Nov 2004

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

The enzyme is known as PTPRO (for “protein tyrosine phosphatase receptor-type O”). When the gene responsible for producing PTPRO is silenced, as can happen in lung cancer, for example, the amount of the enzyme drops, allowing the cells to grow when they shouldn’t.

11 Nov 2004

Women with arrhythmias may also benefit from implantable cardioverter-defibrillators

A small study of patients with heart failure not caused by blocked arteries indicates that women, as well as men, may benefit from implantable cardioverter-defibrillators (ICD), reported researchers at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Calcium channel blocker reduces adverse cardiovascular events

The calcium channel blocker amlodipine decreases the risk of cardiovascular events (such as heart attack or heart-disease related deaths) in patients with coronary artery disease and normal blood pressure, as does the ACE inhibitor enalapril, but to a lesser extent, according to a study in the November 10 issue of JAMA.

10 Nov 2004

ACE inhibitors not needed for many heart disease patients

Many heart disease patients who are already receiving state-of-the-art therapy do not benefit from additional treatment with angiotensin converting enzyme (ACE) inhibitors, according to results of a new study funded by the National Heart, Lung, and Blood Institute (NHLBI).

8 Nov 2004

Researchers have documented a novel form of resistance in leukemia cells to an anti-cancer drug

Researchers at Virginia Commonwealth University’s Massey Cancer Center have documented a novel form of resistance in leukemia cells to an anti-cancer drug, which could help scientists develop new strategies for treating the disease.

8 Nov 2004

Researchers attempt to quantify processes underlying cell heterogeneity

Combining the latest methods in gene splicing and computer modeling, Rice University researchers are trying to develop a predictive framework for one of the most basic and complex biological phenomena — cellular heterogeneity, or the ability of genetic clones to act and behave differently when exposed to the same set of environmental stimuli.

8 Nov 2004

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

Some kidney dialysis patients contract hepatitis B virus (HBV) during the course of their treatment, possibly from other members of the dialysis population with occult HBV.

8 Nov 2004

Celebrex may one day be used to prevent and even treat breast tumors

The anti-inflammatory drug Celebrex, or celecoxib, reduces tumor mass by encouraging cell death and discouraging both cell proliferation and the sprouting of new blood vessels that feed growing tumors, according to a study reported in the November issue of Molecular Cancer Research.

5 Nov 2004

alpha4 may prove to be useful target for smoking addiction therapies

Nicotine is responsible for more than four million smoking-related deaths each year. Yet people still smoke. Why? One reason is the stranglehold of addiction, started when nicotine enhances the release of a neurotransmitter called dopamine

4 Nov 2004

Enzyme News and Research

Stress affects molecules believed to play a key role in cellular aging

Salmonella pathogen uses molecular hydrogen to grow and become virulent

Nanoscale switch could serve as sensor, medical tool

Researchers have discovered that by blocking a specific enzyme, it is possible to check the spread of cancer

Acid-resistant bug also alcohol-resistant

New findings have implications for chronic use of COX-2 Inhibitors in pre-menopausal women

Patented fibrin-based matrices and tissue may open doors for tissue and organ engineering

Startling new blood pressure findings - atherosclerosis slowed

Novel enzyme in sperm is essential for spontaneous and independent movement

Breast cancer study seeks postmenopausal women

Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

Women with arrhythmias may also benefit from implantable cardioverter-defibrillators

Calcium channel blocker reduces adverse cardiovascular events

ACE inhibitors not needed for many heart disease patients

Researchers have documented a novel form of resistance in leukemia cells to an anti-cancer drug

Researchers attempt to quantify processes underlying cell heterogeneity

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

Celebrex may one day be used to prevent and even treat breast tumors

alpha4 may prove to be useful target for smoking addiction therapies

Measuring Drug-Target Residence Times with Biochemical Assays eBook

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