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Already approved drug avapritinib shows promise in treating high-grade gliomas

High-grade glioma, an aggressive form of pediatric and adult brain cancer, is challenging to treat given the tumor location, incidence of recurrence and difficulty for drugs to cross the blood-brain barrier.

13 Mar 2025

Combination immunotherapy improves treatment response for head and neck cancer

Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherapy drug.

13 Mar 2025

Researchers develop new compound to treat alopecia areata

A research group, led by Dr. Pavel Majer from IOCB Prague, in collaboration with the laboratories of Barbara Slusher and Louis Garza at Johns Hopkins University, have developed a compound that could potentially treat the autoimmune disorder alopecia areata, which causes hair loss leading to the formation of bald patches.

13 Mar 2025

New study reveals novel multi-omics approach with unprecedented treatment response prediction in metastatic urothelial cancer

Novigenix, a leader in AI-driven healthcare solutions, has published a groundbreaking study showcasing the predictive power of its LITOSeek™ platform for immunotherapy response in metastatic urothelial cancer.

13 Mar 2025

Clinical trial tests herpes virus-based therapy for neurogenic bladder in people with spinal cord injury

A modified herpes virus that targets spinal cord nerve cells to treat neurogenic bladder in people with spinal cord injury is underway in a first-in-human clinical trial by UTHealth Houston at TIRR Memorial Hermann.

12 Mar 2025

New treatment option for advanced thymic carcinoma shows promise

Thymic epithelial tumors are a rare group of malignancies originating in the thymus gland, that includes thymoma and thymic carcinoma.

12 Mar 2025

Oral antiviral drug proves successful in preventing symptomatic COVID-19 in household members

An international clinical trial has identified a medication that can help prevent symptomatic COVID-19 in people exposed within households.

12 Mar 2025

Tecovirimat monotherapy found ineffective for treating clade II mpox in NIH-sponsored trial

NIH-sponsored trial data offer further evidence to help inform mpox treatment decisions.

12 Mar 2025

Sent home to heal, patients avoid wait for rehab home beds

After a patch of ice sent Marc Durocher hurtling to the ground, and doctors at UMass Memorial Medical Center repaired the broken hip that resulted, the 75-year-old electrician found himself at a crossroads.

12 Mar 2025

Groundbreaking vaccine study offers hope for ending meningitis in Africa

University of Maryland School of Medicine (UMSOM) researchers helped conduct an important new global health study that found a vaccine that protects against five strains of meningitis prevalent in sub-Saharan Africa is safe and effective for use in young children beginning at 9 months of age.

11 Mar 2025

Emergency room downtime can boost cervical cancer screenings, study shows

A University of Rochester Medical Center study showed that downtime in the emergency room can have a potential upside for women who are behind on cervical cancer screenings, which is a nationwide problem.

11 Mar 2025

Automated insulin delivery systems are safe and effective for older adults with type 1 diabetes

New research from Washington State University in collaboration with five other institutions suggests that automated insulin delivery (AID) systems are safe and effective for use by older adults with type 1 diabetes.

11 Mar 2025

Next-generation, inhaled COVID-19 vaccine enters phase-2 clinical trial

Researchers at McMaster University have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine.

10 Mar 2025

MRNA vaccines, once a Trump boast, now face attacks from some in GOP

Researchers racing to develop bird flu vaccines for humans have turned to a cutting-edge technology that enabled the rapid development of lifesaving covid shots.

10 Mar 2025

Study assesses two ways to test patients' hereditary cancer risks

Up to 10% of cancers are caused by genes that can be easily detected by commercially available tests. These include such common cancers as cancer of the breast, ovary, colon, stomach, uterus and pancreas.

8 Mar 2025

Existing drug could prevent liver damage caused by ammonia build-up

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice led by researchers from UCL.

7 Mar 2025

Breakthrough drug more than doubles survival in glioblastoma patients

A drug developed at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has been shown to extend survival for patients with glioblastoma, the most common primary brain tumor in adults.

7 Mar 2025

Insilico Medicine's AI-driven drug Rentosertib receives official generic name

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, recently announced that its breakthrough drug candidate for idiopathic pulmonary fibrosis (IPF) – Rentosertib (formerly known as ISM001-055) – has been granted an official generic name by the United States Adopted Names (USAN) Council.

7 Mar 2025

Novel treatment approach shows promise for advanced HPV-negative head and neck cancer

Researchers from the University of Chicago Medicine Comprehensive Cancer Center demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC).

7 Mar 2025

Customized mobile app intervention benefits older adults experiencing mild cognitive decline

A growing body of research indicates that older adults in assisted living facilities can delay or even prevent cognitive decline through interventions that combine multiple activities, such as improving diet, solving puzzles and increasing social interactions.

6 Mar 2025