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Study identifies cost-effective strategies for using AI in health systems

A study by researchers at the Icahn School of Medicine at Mount Sinai has identified strategies for using large language models (LLMs), a type of artificial intelligence (AI), in health systems while maintaining cost efficiency and performance.

18 Nov 2024

How vitamin B3 could be the secret to living longer and protecting your heart

Dietary niacin intake reduces risks of all-cause and cardiovascular mortality in US adults, with benefits more pronounced in non-diabetic individuals and linked to NAD metabolism improvements.

18 Nov 2024

New MELD model improves liver transplant access for women

Since the adoption of a new model for assessing the severity of liver disease, women are more likely to be added to the waitlist for a liver transplant, more likely to receive a transplant, and less likely to drop off the waitlist - closing the gap between men and women candidates, according to a study scheduled for presentation today at The Liver Meeting held by the American Association for the Study of Liver Diseases.

18 Nov 2024

AI algorithm accurately detects early-stage metabolic-associated steatotic liver disease

Liver disease, which is treatable when discovered early, often goes undetected until late stages, but a new study revealed that an algorithm fueled by artificial intelligence can accurately detect early-stage metabolic-associated steatotic liver disease (MASLD) by using electronic health records.

18 Nov 2024

Vanderbilt receives $3.3 million grant to develop medications for preventing preterm birth

Vanderbilt University Medical Center is receiving $3.3 million over two years through the Advanced Research Projects Agency for Health's (ARPA-H) Sprint for Women's Health for its early-stage research efforts to develop medications designed to suppress premature uterine contractions during pregnancy.

15 Nov 2024

Comprehensive database reveals protein changes associated with aging

With the worldwide population aging at an unprecedented rate, the prevention of age-related diseases has become a prominent issue.

15 Nov 2024

Duke-NUS team develops test to monitor engineered T cells in cancer treatment

A novel test developed by Duke-NUS researchers enables real-time monitoring of T cells that have been engineered to fight cancer, after re-introduction into the body of a cancer patient.

15 Nov 2024

Liver cell aging can trigger multi-organ failure

The aging and failure of cells that occurs when the liver is damaged can spread to other organs, suggests a new study in mice and humans from researchers at UCL, the University of Edinburgh and the CRUK Scotland Institute.

15 Nov 2024

Microbial density in our gut shapes how diseases are linked to gut health

The study in Cell highlights microbial load's role in gut microbiome variation, suggesting it as a confounder in disease research and a key health determinant.

15 Nov 2024

Air pollution linked to head and neck cancer risk

Increased PM2.5 levels are linked to higher head and neck cancer risk, particularly in disadvantaged communities, highlighting urgent public health measures.

15 Nov 2024

Leveraging genetic variations for more effective cancer therapies

By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups.

14 Nov 2024

BMI's influence on disease pathogenesis uncovered in new research

The study highlights BMI's role in mediating genetic risk for diseases, suggesting a complex relationship with conditions like heart failure and osteoarthritis.

14 Nov 2024

CN Bio launches PhysioMimix Bioavailability assay kit: Human 18

CN Bio, a leading provider of Organ-on-a-chip Systems and solutions that accelerate drug discovery and development workflows, today announced the launch of its PhysioMimix® Bioavailability assay kit: Human 18. Harnessing the capabilities of the PhysioMimix Multi-organ System, the kit enhances lead optimization and preclinical testing pipelines, providing an all-in-one solution to generate predictive insights into human oral bioavailability, and better inform lead candidate selection.

14 Nov 2024

UAB researchers reverse liver disease in mice with gene therapy

UAB researchers have reversed metabolic dysfunction-associated steatohepatitis (MASH) in mouse models. MASH is a severe liver disease associated with obesity and type 2 diabetes that affects more than 40 million people.

13 Nov 2024

Healthy low-carb diet and time-restricted eating improve weight loss and gut health beyond calorie restriction

Researchers discovered that a healthy low-carb diet and time-restricted eating, combined with moderate calorie restriction, offer significant weight loss and gut health benefits for overweight adults, with some effects lasting up to 28 weeks post-intervention.

13 Nov 2024

Study provides new insights into the central role of goblet cells

In a recent study, researchers at the University of California, San Diego, have provided new insights into the central role of goblet cells - specialized cells that line the gut - in maintaining a healthy and balanced immune environment within the gastrointestinal (GI) tract.

12 Nov 2024

Novel compound BHB-Phe could offer new approach to weight loss

Researchers at Baylor College of Medicine, Stanford University School of Medicine and collaborating institutions report in the journal Cell the discovery of BHB-Phe, a novel compound produced by the body that regulates appetite and body weight through interactions with neurons in the brain.

12 Nov 2024