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The role of emotion regulation in predicting suicidal risk in depressed individuals

Depressed individuals who reflexively attempt to dampen their initial emotional responses to reminders of their negative memories have a low tolerance for distressing emotional stimuli in general and may respond to stress in their daily lives with greater upticks in suicidal thoughts.

26 Nov 2024

Nasal spray shows promise in combating Alzheimer's

A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, they can counteract the cognitive decline and brain damage typical of the disease.

26 Nov 2024

New funding expands study of brain changes in bipolar disorder

Leila Nabulsi, PhD, a postdoctoral researcher in computational neuroscience at the Keck School of Medicine of USC's Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) has received funding to expand research on the neurocircuitry that underlies bipolar disorder.

25 Nov 2024

New brain biomarker could enable early diagnosis of psychosis

The current standard of care for psychosis is a diagnostic interview, but what if it could be diagnosed before the first symptom emerged? Researchers at the Del Monte Institute for Neuroscience at the University of Rochester are pointing toward a potential biomarker in the brain that could lead to more timely interventions and personalized care.

25 Nov 2024

Dopamine and serotonin balance reward learning in opposing ways

If you've heard of two of the brain's chemical neurotransmitters, it's probably dopamine and serotonin. Never mind that glutamate and GABA do most of the work - it's the thrill of dopamine as the "pleasure chemical" and serotonin as tender mood-stabilizer that attract all the headlines.

25 Nov 2024

Hamilton and Amabel James Center for AI and Human Health launches at Mount Sinai

Today, the Mount Sinai Health System, one of New York City's largest academic medical systems, announced the opening of the Hamilton and Amabel James Center for Artificial Intelligence and Human Health, which is dedicated to enhancing health care delivery through the research, development, and application of innovative artificial intelligence (AI) tools and technologies.

25 Nov 2024

Research identifies the brain's 'locus coeruleus' as key player in sleep cycles

Researchers at the University of Lausanne have identified a novel role for the brain's 'locus coeruleus' in sleep and its disruptions.

25 Nov 2024

Researchers develop new approach to effectively deliver therapeutics into the brain

Researchers at the Icahn School of Medicine at Mount Sinai have developed an innovative approach - demonstrated in mouse models and isolated human brain tissue - to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psychiatric diseases.

25 Nov 2024

Groundbreaking method profiles gene activity in the living brain

A groundbreaking method to profile gene activity in the living human brain has been developed by researchers at FutureNeuro, the Research Ireland Centre for Translational Brain Science and RCSI University of Medicine and Health Sciences, in collaboration with international partners.

25 Nov 2024

NREM sleep boosts cognitive performance through brain synchronization

While it's well known that sleep enhances cognitive performance, the underlying neural mechanisms, particularly those related to nonrapid eye movement (NREM) sleep, remain largely unexplored.

23 Nov 2024

Probiotics shown to mitigate effects of toxic fire-retardant chemicals

Polybrominated diphenyl ethers, or PBDEs, are fire-retardant chemicals that are found everywhere - upholstery, carpets, curtains, electronics, and even infant products.

23 Nov 2024

Study reveals how the brain connects social thinking with emotional processing

We've all been there. Moments after leaving a party, your brain is suddenly filled with intrusive thoughts about what others were thinking. "Did they think I talked too much?" "Did my joke offend them?" "Were they having a good time?"

23 Nov 2024

Study reveals how brainstem neurons control eye movements

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes' gaze.

22 Nov 2024

Anxiety and negative emotions reduced by brain circuit that consciously slows breathing

Findings on the dACC→PnC circuit show how breathing patterns influence anxiety, paving the way for new therapeutic approaches to emotional regulation.

22 Nov 2024

Researchers reveal cellular foundations of functional brain networks in humans

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

21 Nov 2024

CU Boulder study sheds light on sex differences in sleep patterns

Females sleep less, wake up more often and get less restorative sleep than males, according to a new animal study by CU Boulder researchers.

21 Nov 2024

First 'blueprint' of human skeletal development offers new insights into bone formation

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

21 Nov 2024

Cannabis use linked to brain changes in young adults at risk of psychosis

Young adults at risk of psychosis show reduced brain connectivity, a deficit that cannabis use appears to worsen, a new study has found.

20 Nov 2024

Telemedicine use in neurology affected by race and neighborhood disparities

For people seeing a neurologist, their age, race, ethnicity and neighborhood may play a role in whether they do so in person or virtually, via telemedicine, according to a study published in the November 20, 2024, online issue of Neurology® Clinical Practice , an official journal of the American Academy of Neurology.

20 Nov 2024