Clinical Trial News and Research

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Boehringer Ingelheim initiates two afatinib phase II studies in HER2-positive breast cancer

Boehringer Ingelheim today announced the initiation of two phase II studies, 1200.89 and LUX-Breast 2, evaluating afatinib in patients with metastatic breast cancer, who have an overexpression of the erbB2 (HER2) protein, so called HER2-positive patients. Afatinib is an irreversible ErbB Family Blocker, which binds to all erbB-family kinases including erbB2.

29 Aug 2011

Study shows link between laughter and vascular health

Watching a funny movie or sitcom that produces laughter has a positive effect on vascular function and is opposite to that observed after watching a movie that causes mental stress according to research conducted at the University of Maryland School of Medicine in Baltimore, Maryland.

29 Aug 2011

Post MI snus quitters have lower risk of mortality

In this prospective cohort study, presented today at the ESC Congress 2011, discontinuation of smokeless tobacco after a myocardial infarction (MI) is associated with a lower risk of subsequent mortality.

29 Aug 2011

One in three AF patients at high risk of stroke are not being prescribed VKA therapy

New data show that, worldwide, one in three patients with atrial fibrillation (AF) who are at high risk for stroke are not being prescribed anticoagulant therapy, particularly vitamin K antagonists (VKA) – medicines known to significantly lower stroke risk in these patients.

29 Aug 2011

ELIQUIS better than warfarin in reduction of stroke, major bleeding, and mortality

Bristol-Myers Squibb Company and Pfizer Inc. today announced the main results of the Phase 3 clinical trial ARISTOTLE, which evaluated ELIQUIS compared to warfarin for the prevention of stroke or systemic embolism in 18,201 patients with atrial fibrillation and at least one risk factor for stroke.

29 Aug 2011

MitraClip treatment could benefit heart failure patients who are unresponsive to CRT

Results of an observational study presented at the European Society of Cardiology (ESC) meeting today in Paris demonstrate that the percutaneous catheter-based MitraClip treatment improves symptoms and promotes reverse left ventricular (LV) remodeling in patients with mitral regurgitation (MR), who do not respond to cardiac resynchronization therapy.

29 Aug 2011

CIRM approves stem cell research planning grants for five UC Davis teams

The California Institute for Regenerative Medicine (CIRM), the state stem cell agency, today approved research planning grants for five UC Davis Health System teams that are working to develop human clinical trials to treat illnesses such as Huntington's disease, vascular disease, osteoporosis, HIV/AIDS and airway disease in children.

29 Aug 2011

Apixaban superior to warfarin in preventing stroke and systemic embolism

A large-scale trial finds that apixaban, a new anticoagulant drug, is superior to the standard drug warfarin for preventing stroke and systemic embolism in patients with atrial fibrillation.

29 Aug 2011

Azithromycin can help reduce wheezing, other acute symptoms of COPD

A common antibiotic can help reduce the severe wheezing and other acute symptoms of chronic obstructive pulmonary disease, according to a large, multicenter clinical trial sponsored by the National Institutes of Health and conducted at the University of California, San Francisco (UCSF).

29 Aug 2011

NIH creates mathematical model to predict weight changes in the body

Researchers at the National Institutes of Health have created a mathematical model - and an accompanying online weight simulation tool - of what happens when people of varying weights, diets and exercise habits try to change their weight. The findings challenge the commonly held belief that eating 3,500 fewer calories - or burning them off exercising - will always result in a pound of weight loss.

26 Aug 2011

SuperSonic Imagine introduces UltraFast Doppler technology

SuperSonic Imagine, the ultrasound company that pioneered breakthrough ShearWave Elastography technology, today announced another major breakthrough in ultrasound imaging: UltraFast Doppler.

26 Aug 2011

Fludrocortisone may help reduce unexplained chronic nausea in children

Heart rate and blood pressure regulation may hold the key to treating unexplained chronic nausea in children. In a new study by researchers at Wake Forest Baptist Medical Center, a drug commonly used to treat a condition known as orthostatic intolerance (OI), which causes dizziness and occasional fainting when patients stand for long periods, was shown to reduce debilitating chronic nausea in patients.

26 Aug 2011

European Journal of Heart Failure publishes results of BIOTRONIK Home-CARE clinical study

BIOTRONIK SE & Co. KG, a worldwide leader in manufacturing cardiac medical devices and pioneer of remote patient management solutions, announced today that results of the Home-CARE (Home Monitoring in Cardiac Resynchronization Therapy) clinical study were published in the European Journal of Heart Failure.

26 Aug 2011

Emergent announces results of adjuvanted BioThrax anthrax vaccine Phase 1a trial

Emergent BioSolutions Inc. announced today that results from a Phase 1a clinical trial evaluating an investigational anthrax vaccine, Anthrax Vaccine Adsorbed with CPG 7909 Adjuvant mixed at bedside, have been published in Vaccine, a leading medical journal on vaccines and immunology.

26 Aug 2011

Boehringer Ingelheim, Lilly receive EU approval for linagliptin to treat type 2 diabetes

Boehringer Ingelheim and Eli Lilly and Company today received Marketing Authorization from the European Commission for linagliptin 5 mg film-coated tablets for the treatment of adults with type 2 diabetes.

26 Aug 2011

CVRx introduces CE Mark approved Barostim neo for treatment of uncontrolled hypertension

CVRx, Inc., a private medical device company, introduced today its second-generation implantable device, the Barostim neo, for the treatment of uncontrolled hypertension. The Barostim neo features a new unilateral, 1mm electrode and a new smaller, more advanced stimulator to allow for more focused and efficient delivery of therapy. These improvements have led to shorter procedure times and extended longevity.

25 Aug 2011

People with Down syndrome have diminished optokinetic, vestibular reflexes

A scientist investigating why those with Down syndrome often have poor balance and motor coordination has found that key eye reflexes are substantially altered.

25 Aug 2011

US Oncology Research earns RTOG's Full Member status

US Oncology Research, one of the nation's largest networks of community-based researchers, and Radiation Therapy Oncology Group (RTOG), the leader in radiation oncology-focused clinical trials in the United States, announced today that US Oncology Research has earned Full Member status, an accomplishment few institutions achieve.

25 Aug 2011

FDA approves Allergan's BOTOX to treat specific form of urinary incontinence

Allergan, Inc. today announced the United States Food and Drug Administration (FDA) has approved BOTOX for injection for the treatment of urinary incontinence due to detrusor overactivity associated with a neurologic condition in adults who have an inadequate response to or are intolerant of an anticholinergic medication.

25 Aug 2011

Neovasc second quarter revenues decrease 8% to $879,405

Neovasc Inc., today announced financial results for the three and six months ended June 30, 2011.

24 Aug 2011

Clinical Trial News and Research

Boehringer Ingelheim initiates two afatinib phase II studies in HER2-positive breast cancer

Study shows link between laughter and vascular health

Post MI snus quitters have lower risk of mortality

One in three AF patients at high risk of stroke are not being prescribed VKA therapy

ELIQUIS better than warfarin in reduction of stroke, major bleeding, and mortality

MitraClip treatment could benefit heart failure patients who are unresponsive to CRT

CIRM approves stem cell research planning grants for five UC Davis teams

Apixaban superior to warfarin in preventing stroke and systemic embolism

Azithromycin can help reduce wheezing, other acute symptoms of COPD

NIH creates mathematical model to predict weight changes in the body

SuperSonic Imagine introduces UltraFast Doppler technology

Fludrocortisone may help reduce unexplained chronic nausea in children

European Journal of Heart Failure publishes results of BIOTRONIK Home-CARE clinical study

Emergent announces results of adjuvanted BioThrax anthrax vaccine Phase 1a trial

Boehringer Ingelheim, Lilly receive EU approval for linagliptin to treat type 2 diabetes

CVRx introduces CE Mark approved Barostim neo for treatment of uncontrolled hypertension

People with Down syndrome have diminished optokinetic, vestibular reflexes

US Oncology Research earns RTOG's Full Member status

FDA approves Allergan's BOTOX to treat specific form of urinary incontinence

Neovasc second quarter revenues decrease 8% to $879,405

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