Clinical Trial News and Research

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Cerulean initiates CRLX101 Phase 2 trial in non-small cell lung cancer

Cerulean Pharma Inc., a leader in designing and developing tumor-targeted nanopharmaceuticals, today announced the dosing of the first patients with CRLX101 in a randomized, controlled non-small cell lung cancer (NSCLC) Phase 2 clinical trial.

13 Jul 2011

UIC to begin STX209 clinical trial for treatment of autism spectrum disorders

An experimental drug to treat social withdrawal in children and young adults with autism is being studied in a clinical trial at the University of Illinois at Chicago's Institute for Juvenile Research.

13 Jul 2011

Enrollment commences in Exact Sciences' colorectal cancer screening trial

Exact Sciences today announced the initiation of the pivotal trial for the company's multi-marker molecular diagnostic screening test for the early detection of colorectal cancer.

13 Jul 2011

Arena reports APD811 Phase 1 trial results against pulmonary arterial hypertension

Arena Pharmaceuticals, Inc. announced today results from a Phase 1 clinical trial of APD811, an orally bioavailable agonist of the prostacyclin receptor which is intended for the treatment of pulmonary arterial hypertension, or PAH.

13 Jul 2011

Cardiologists still perform artery-opening procedure despite changes in guidelines

Despite changes in standard treatment practice guidelines issued by the American College of Cardiology, American Heart Association and the European Society of Cardiology several years ago, there has been no meaningful change in the nation's practice of opening completely blocked coronary arteries with balloons and stents in the days after a heart attack, according to a new study published in the July 11, 2011, issue of Archives of Internal Medicine.

12 Jul 2011

FDA approves protocol for Medtronic's SYMPLICITY HTN-3 for treatment of hypertension

Medtronic, Inc., announced today that the U.S. Food and Drug Administration (FDA) has conditionally approved the protocol for SYMPLICITY HTN-3, the company's U.S. clinical trial of renal denervation with the Symplicity Catheter System for the treatment of resistant hypertension, an especially dangerous disease affecting hundreds of millions of people worldwide.

From Medtronic 12 Jul 2011

BioAlliance receives European patent for Livatag to treat primary liver cancer

BioAlliance Pharma SA, a company dedicated to specialty and orphan oncology products, today announces the grant of a European patent protecting its Transdrug nanotechnology.

12 Jul 2011

Toumaz announces JV for newly approved ‘digital plaster’

Toumaz Limited (AIM: TMZ,) has established a new joint venture with Dr. Patrick Soon-Shiong’s company California Capital Equity LLC (‘CCE’), to expand the commercialisation and distribution of the Sensium™ Digital Plaster. The joint venture, which is named “Toumaz US LLC”, will be headquartered in San Diego, California, and will sell and distribute the Sensium™ Digital Plaster in North America and Worldwide.

11 Jul 2011

FDA clears TearScience's LipiFlow Thermal Pulsation System for evaporative dry eye

TearScience, Inc., a privately-held medical device company, today announced that it has received U.S. Food and Drug Administration (FDA) clearance for its LipiFlow Thermal Pulsation System for the treatment of meibomian gland dysfunction (MGD), also known as evaporative dry eye.

11 Jul 2011

Sinapis completes first clinical trial of lead drug for stroke and traumatic brain injury

Sinapis Pharma, Inc. is pleased to announce that it has completed its first clinical trial in the development of its lead drug for the treatment of stroke and traumatic brain injury.

11 Jul 2011

Anavex exercises warrants to raise $1.575 million

Anavex Life Sciences Corp. is pleased to announce that it has raised $1,575,000 through the exercise of warrants. Funds will be used to continue the Phase I clinical trial of ANAVEX 2-73, the company's lead drug candidate for Alzheimer's disease, to advance other compounds in the Anavex pipeline, and for general corporate purposes.

11 Jul 2011

Alnylam seeks CTA clearance to initiate ALN-PCS Phase I clinical trial for severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has filed a Clinical Trial Application (CTA) with the Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase I clinical trial with ALN-PCS, an RNAi therapeutic for the treatment of severe hypercholesterolemia.

11 Jul 2011

Pain Practice journal publishes Vertos mild procedure clinical study data on LSS

Medical device company Vertos Medical Inc. has announced that one-year post-study follow-up data on its mild procedure for lumbar spinal stenosis (LSS) have been published in the peer-reviewed journal Pain Practice.

11 Jul 2011

WPD intervention might improve effects of stress management group therapy

A randomized clinical trial published in a recent issue of Psychotherapy and Psychosomatics examines a new method for enhancing the effects of stress management therapy. Evidence is accumulating that worry is an important mediator between the experience of stressors and poor mental and somatic health.

11 Jul 2011

Covidien to support NOTES human trial on transoral, transvaginal cholecystectomies

The Natural Orifice Surgery Consortium for Assessment and Research- (NOSCAR-), a joint effort of the American Society for Gastrointestinal Endoscopy and the Society of American Gastrointestinal and Endoscopic Surgeons, is pleased to announce a grant from Covidien to support the U.S. multicenter human trial on transoral and transvaginal cholecystectomies using Natural Orifice Translumenal Endoscopic Surgery.

11 Jul 2011

Positive top-line results from alemtuzumab Phase 3 trial on multiple sclerosis

Sanofi and its subsidiary Genzyme announced today positive top-line results from CARE-MS I, the first of two randomized, Phase 3 clinical trials comparing the investigational drug alemtuzumab to the approved multiple sclerosis therapy Rebif in patients with relapsing-remitting multiple sclerosis.

11 Jul 2011

Preliminary results from Generex Oral-lyn clinical trial on type 1 diabetes

Generex Biotechnology Corporation today announced preliminary clinical results of two major trials using the Generex Oral-lyn formulation that will be used for registration and marketing.

11 Jul 2011

EU countries should pool funding to create 'prize' for bringing new antibiotics to market, report says

"European policy makers were urged Wednesday to find viable financial incentives to get drug companies to discover new antibiotics, because the lack of fresh supplies poses acute dangers to health care and efforts against infectious diseases," according to a report by the Office of Health Economics and funded by GlaxoSmithKline, Dow Jones/Wall Street Journal reports.

8 Jul 2011

Merck decides not to advance IMO-2055 development for squamous cell carcinoma of the head and neck

Idera Pharmaceuticals today provides an update on the clinical development of IMO-2055 (EMD 1201081), a TLR9 agonist for cancer treatment being developed by Merck KGaA, Darmstadt, Germany, under its collaboration with Idera.

8 Jul 2011

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

Identifying a suitable donor for leukemia and lymphoma patients who need bone marrow transplants may be far easier now that results of two clinical trials show transplant results with half-matched bone marrow or umbilical cord blood are comparable to fully matched tissue, thanks in large part to the availability of effective antirejection drugs and special post-transplant chemotherapy.

8 Jul 2011

Clinical Trial News and Research

Cerulean initiates CRLX101 Phase 2 trial in non-small cell lung cancer

UIC to begin STX209 clinical trial for treatment of autism spectrum disorders

Enrollment commences in Exact Sciences' colorectal cancer screening trial

Arena reports APD811 Phase 1 trial results against pulmonary arterial hypertension

Cardiologists still perform artery-opening procedure despite changes in guidelines

FDA approves protocol for Medtronic's SYMPLICITY HTN-3 for treatment of hypertension

BioAlliance receives European patent for Livatag to treat primary liver cancer

Toumaz announces JV for newly approved ‘digital plaster’

FDA clears TearScience's LipiFlow Thermal Pulsation System for evaporative dry eye

Sinapis completes first clinical trial of lead drug for stroke and traumatic brain injury

Anavex exercises warrants to raise $1.575 million

Alnylam seeks CTA clearance to initiate ALN-PCS Phase I clinical trial for severe hypercholesterolemia

Pain Practice journal publishes Vertos mild procedure clinical study data on LSS

WPD intervention might improve effects of stress management group therapy

Covidien to support NOTES human trial on transoral, transvaginal cholecystectomies

Positive top-line results from alemtuzumab Phase 3 trial on multiple sclerosis

Preliminary results from Generex Oral-lyn clinical trial on type 1 diabetes

EU countries should pool funding to create 'prize' for bringing new antibiotics to market, report says

Merck decides not to advance IMO-2055 development for squamous cell carcinoma of the head and neck

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

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