Clinical Trial News and Research

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Text messages help smokers quit: Study

A behavioral study has found that motivational text messages sent to smokers' mobile phones can double their chances of giving up tobacco. The “txt2stop” trial at London School of Hygiene and Tropical Medicine (LSHTM) and funded by the Medical Research Council tested the effects of inspirational text messages designed to encourage quitting on almost 3,000 smokers. Participants were twice as likely to banish their habit as another group sent texts unrelated to smoking.

30 Jun 2011

ESC Congress 2011 to spotlight 'controversial issues in cardiology'

The scientific programme for this year's ESC Congress, which will take place in Paris from 27-31 August, is now complete and promises to provide journalists with a rich source of front-page news stories and background for topical features.

30 Jun 2011

NLST: CT screening reduces lung cancer specific mortality by 20%

Current and former heavy smokers can now be screened more effectively for lung cancer. Results from the National Lung Screening Trial (NLST) revealed that detecting small lung cancers with computed tomography (CT) reduces lung cancer specific mortality by 20 percent.

30 Jun 2011

MR-guided focused ultrasound effective for treating essential tremor

The last ten years have been challenging for Billy R. Williams of Fort Valley, Virginia. The former Pentagon employee, who survived the 9/11 terrorist attack, has suffered from essential tremor, a progressive and debilitating neurological disorder.

30 Jun 2011

Molecular radiotherapy offers hope for children with neuroblastoma

A new treatment option may soon be available for children with neuroblastoma according to research published in the July issue of The Journal of Nuclear Medicine.

30 Jun 2011

Novartis reports NVA237 Phase III trial results against COPD

Sosei Group Corporation, announces that results reported today by Novartis from the pivotal Phase III GLOW2 clinical trial show that once-daily NVA237 50 mcg significantly improved lung function in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) relative to placebo, with similar efficacy to open-label tiotropium.

30 Jun 2011

Acetylon to advance ACY-1215 drug candidate with $27M Series B Preferred equity investment round of financing

Acetylon Pharmaceuticals, Inc. announced today that it has completed a $27 million Series B Preferred equity investment round of financing.

29 Jun 2011

Zalicus commences Synavive SYNERGY Phase 2b clinical trial for rheumatoid arthritis

Zalicus Inc. a biopharmaceutical company that discovers and develops novel treatments for patients suffering from pain and immuno-inflammatory diseases today announced the initiation of the SYNERGY trial, a Phase 2b clinical trial evaluating Synavive, a low-dose glucocorticoid with the potential for amplified immuno-inflammatory benefits, in patients with rheumatoid arthritis (RA).

29 Jun 2011

Threshold commences combination Phase 1/2 trial of TH-302 and sunitinib for RCC, GIST and PNET

Threshold Pharmaceuticals, Inc., today announced the initiation of a Phase 1/2 dose escalation clinical trial of TH-302 in combination with sunitinib in patients with advanced renal cell carcinoma (RCC), gastrointestinal stromal tumor (GIST) and pancreatic neuroendocrine tumor (PNET).

29 Jun 2011

Two-pronged 'hybrid' procedure for treatment of atrial fibrillation

Doctors at Washington University School of Medicine in St. Louis are performing a new procedure to treat atrial fibrillation, a common irregular heartbeat.

29 Jun 2011

USPTO awards patent for key therapeutic ingredient in CNVN202 targeted molecular cancer therapy

Convergen LifeSciences, Inc. announced today that a United States Patent has been awarded by the U.S. Patent and Trademark Office jointly to The University of Texas System Board of Regents and The Secretary, U.S. Department of Health and Human Services.

29 Jun 2011

Macrogenics' Protege Phase 3 clinical study of teplizumab in type 1 diabetes published in The Lancet

MacroGenics, Inc., a privately held biotechnology company that develops immunotherapeutics to treat autoimmune disorders, cancer and infectious diseases, announced the publication in The Lancet of results from Protege, a Phase 3 clinical study of teplizumab in type 1 diabetes.

29 Jun 2011

Positive results from RISE and RIDE Phase III trials of Genentech's Lucentis for diabetic macular edema

Genentech, a member of the Roche Group, today announced 24-month results from the two pivotal Phase III trials (RISE and RIDE) assessing the efficacy and safety of Lucentis (ranibizumab injection) in people with diabetic macular edema (DME).

29 Jun 2011

Nuvilex to continue development of acquired live-cell encapsulation technology

Nuvilex, Inc. announced its plans to continue development of the live-cell encapsulation technology obtained with its recent acquisition of SG Austria, to carry out the pancreatic cancer clinical trial, to maintain and expand customers utilizing the encapsulation technology, and to establish itself as an active participant in the stem cell arena. The stem cell market was estimated to be $21.5 billion globally in 2010 and is forecast to reach $63.8 billion by 2015.

29 Jun 2011

Cotton swab dramatically reduces infections in post-operative incision sites

A simple item found in almost every medicine cabinet - a cotton swab -- may be a key tool in the fight against post-surgical wound infections.

29 Jun 2011

bioMD changes name to Allied Healthcare Group

bioMD Limited (ASX: BOD) today announced a change of corporate name to reflect the merger with Allied Medical Ltd earlier this month. The new Company will be called Allied Healthcare Group Ltd and trade under the ASX code AHZ.

28 Jun 2011

Relypsa initiates dosing in RLY5016 Phase 2b trial for hyperkalemia in diabetic nephropathy and CKD patients

Relypsa, Inc. today announced the start of dosing in a Phase 2b clinical trial of RLY5016 for the treatment of hyperkalemia in patients with diabetic nephropathy and chronic kidney disease (CKD). RLY5016 is a high capacity, non-absorbed, polymer-based potassium binder that is orally administered and has been shown to control serum potassium levels in previous studies.

28 Jun 2011

Enrollment commences in Palatin's bremelanotide Phase 2b trial for female sexual dysfunction

Palatin Technologies, Inc. announced today that enrollment of patients has commenced in Palatin's Phase 2b clinical trial evaluating the efficacy and safety of bremelanotide (previously called PT-141), an on-demand, first-in-class melanocortin agonist being developed for the treatment of female sexual dysfunction (FSD).

28 Jun 2011

BioLineRx initiates enrollment in BL-1020 Phase II/III trial against schizophrenia

BioLineRx, a biopharmaceutical development company, announced today the enrollment of the first patient in the Phase II/III CLARITY clinical trial of BL-1020, a first in class, orally available, GABA-enhanced antipsychotic for the treatment of schizophrenia.

28 Jun 2011

Pfizer to present PF-299 and crizotinib clinical trial data on ALK at WCLC 2011

Pfizer Inc. will present early and mid-stage data from its lung cancer portfolio, including PF-00299804 an investigational, oral, pan-HER inhibitor; and crizotinib, an investigational, oral, first-in-class compound that inhibits the anaplastic lymphoma kinase, or ALK, at the International Association for the Study of Lung Cancer's 14th World Conference on Lung Cancer, July 3-7 in Amsterdam, The Netherlands.

28 Jun 2011

Clinical Trial News and Research

Text messages help smokers quit: Study

ESC Congress 2011 to spotlight 'controversial issues in cardiology'

NLST: CT screening reduces lung cancer specific mortality by 20%

MR-guided focused ultrasound effective for treating essential tremor

Molecular radiotherapy offers hope for children with neuroblastoma

Novartis reports NVA237 Phase III trial results against COPD

Acetylon to advance ACY-1215 drug candidate with $27M Series B Preferred equity investment round of financing

Zalicus commences Synavive SYNERGY Phase 2b clinical trial for rheumatoid arthritis

Threshold commences combination Phase 1/2 trial of TH-302 and sunitinib for RCC, GIST and PNET

Two-pronged 'hybrid' procedure for treatment of atrial fibrillation

USPTO awards patent for key therapeutic ingredient in CNVN202 targeted molecular cancer therapy

Macrogenics' Protege Phase 3 clinical study of teplizumab in type 1 diabetes published in The Lancet

Positive results from RISE and RIDE Phase III trials of Genentech's Lucentis for diabetic macular edema

Nuvilex to continue development of acquired live-cell encapsulation technology

Cotton swab dramatically reduces infections in post-operative incision sites

bioMD changes name to Allied Healthcare Group

Relypsa initiates dosing in RLY5016 Phase 2b trial for hyperkalemia in diabetic nephropathy and CKD patients

Enrollment commences in Palatin's bremelanotide Phase 2b trial for female sexual dysfunction

BioLineRx initiates enrollment in BL-1020 Phase II/III trial against schizophrenia

Pfizer to present PF-299 and crizotinib clinical trial data on ALK at WCLC 2011

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