Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Scientists receive $2.3M grant to develop new technology to diagnose cancer, rheumatoid arthritis and colitis

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $2.3 million grant from the National Institute of General Medical Sciences of the National Institutes of Health to develop new technology to diagnose cancer, rheumatoid arthritis and colitis.

2 May 2014

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Danone Institute International announced today that prominent scientist Gokhan S. Hotamisligil, MD, PhD, is the recipient of the 9th Danone International Prize for Nutrition for his outstanding research in immunology and metabolic diseases.

30 Apr 2014

Armetheon reaches agreement with FDA on SPA for final pivotal trial of tecarfarin

Armetheon, Inc., today announced that it has reached agreement with the U.S. Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for the final pivotal trial of tecarfarin.

29 Apr 2014

New study sheds light on mysterious gene that influences cardiovascular health

A new study from researchers at the University of Ottawa Heart Institute (UOHI), published today in Cell Reports, sheds light on a mysterious gene that likely influences cardiovascular health.

26 Apr 2014

Johns Hopkins scientists find a way to prevent atherosclerosis

Working with mice and rabbits, Johns Hopkins scientists have found a way to block abnormal cholesterol production, transport and breakdown, successfully preventing the development of atherosclerosis, the main cause of heart attacks and strokes and the number-one cause of death among humans. The condition develops when fat builds inside blood vessels over time and renders them stiff, narrowed and hardened, greatly reducing their ability to feed oxygen-rich blood to the heart muscle and the brain.

23 Apr 2014

Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

Nonsteroidal antinflamatory drugs (NSAIDs) that block an enzyme called COX-2 relieve pain and inflammation but can cause heart attacks, stroke, heart failure, and even sudden cardiac death.

22 Apr 2014

Synageva announces publication of LAL Deficiency review in Atherosclerosis

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare diseases, today announced the publication of an overview of lysosomal acid lipase deficiency (LAL Deficiency) in the online version and an upcoming print edition of Atherosclerosis, the official journal of the European Atherosclerosis Society.

21 Apr 2014

NICE recommends FIRMAGON for treating advanced hormone-dependent prostate cancer in adults with spinal metastases

The National Institute for Health and Care Excellence (NICE) today issued its Final Appraisal Determination (FAD) recommending FIRMAGON (degarelix) as an option for treating advanced hormone-dependent prostate cancer, only in adults with spinal metastases who present with signs or symptoms of spinal cord compression.

16 Apr 2014

RWJUH offers new alternative to open up blocked arteries

Treatment options for high-risk heart patients with severely calcified coronary artery disease (CAD) have been limited for more than 20 years. Now, Robert Wood Johnson University Hospital offers a new alternative to open up blocked arteries.

11 Apr 2014

Studies provide evidence to clarify role of NAFLD as independent risk factor for development of CVD

Two new studies presented today at the International Liver CongressTM 2014 have provided more evidence to clarify the role of non-alcoholic fatty liver disease (NAFLD) as an independent risk factor for the development of cardiovascular disease (CVD).

10 Apr 2014

Genkyotex’s GKT137831 reverses lung fibrosis in new model of idiopathic pulmonary fibrosis

Genkyotex, the leading developer of selective NOX enzyme inhibitors, announced today the publication of data showing that GKT137831, a first in class NOX1 and 4 inhibitor, was able to reverse lung fibrosis associated with aging in a new model of idiopathic pulmonary fibrosis.

10 Apr 2014

Study: Moderate to severe depression increases risk of heart failure by 40%

Moderate to severe depression increases the risk of heart failure by 40%, a study of nearly 63 000 Norwegians has shown. The findings were presented for the first time today at EuroHeartCare 2014.

7 Apr 2014

Men with long-term HIV infections at higher risk of developing plaque in their coronary arteries

Men with long-term HIV infections are at higher risk than uninfected men of developing plaque in their coronary arteries, regardless of their other risk factors for coronary artery disease, according to results of a study led by Johns Hopkins researchers. A report on the research appears in the April 1 issue of Annals of Internal Medicine.

1 Apr 2014

Amgen reports positive findings from AMG 145 Phase 3 studies in patients at risk for cardiovascular disease

Amgen (NASDAQ: AMGN) today announced new detailed data from three Phase 3 studies that showed treatment with its novel investigational cholesterol-lowering medication, evolocumab (AMG 145), resulted in a statistically significant reduction of 55-66 percent in low-density lipoprotein cholesterol (LDL-C) compared to placebo in patients with high cholesterol.

31 Mar 2014

Mechanical circulatory assist device may have untapped potential in heart surgery patients, say physicians

The most frequently used mechanical circulatory assist device in the world may have untapped potential, physicians say.

31 Mar 2014

Study of astronauts show heart becomes more spherical when exposed to microgravity in space

New findings from a study of 12 astronauts show the heart becomes more spherical when exposed to long periods of microgravity in space, a change that could lead to cardiac problems, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

31 Mar 2014

Celiac disease people may have near two-fold increased risk of coronary artery disease

People with celiac disease may have a near two-fold increased risk of coronary artery disease compared with the general population, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

31 Mar 2014

Women who have 4 or more live births more likely to show early signs of heart disease

Women who give birth to four or more children are much more likely to have evidence of plaque in their heart or thickening of their arteries - early signs of cardiovascular disease - compared with those having fewer pregnancies, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

29 Mar 2014

New finding reinforces importance of developing healthy eating habits early in life

Women who ate a diet high in fresh fruits and vegetables as young adults were much less likely to have plaque build-up in their arteries 20 years later compared with those who consumed lower amounts of these foods, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

29 Mar 2014

Findings underscore importance of universal pediatric cholesterol screening

Roughly one out of three kids screened for high cholesterol between the ages of 9 and 11 has borderline or high cholesterol, potentially placing them at greater risk for future cardiovascular disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

29 Mar 2014

Atherosclerosis News and Research

Further Reading

Scientists receive $2.3M grant to develop new technology to diagnose cancer, rheumatoid arthritis and colitis

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Armetheon reaches agreement with FDA on SPA for final pivotal trial of tecarfarin

New study sheds light on mysterious gene that influences cardiovascular health

Johns Hopkins scientists find a way to prevent atherosclerosis

Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

Synageva announces publication of LAL Deficiency review in Atherosclerosis

NICE recommends FIRMAGON for treating advanced hormone-dependent prostate cancer in adults with spinal metastases

RWJUH offers new alternative to open up blocked arteries

Studies provide evidence to clarify role of NAFLD as independent risk factor for development of CVD

Genkyotex’s GKT137831 reverses lung fibrosis in new model of idiopathic pulmonary fibrosis

Study: Moderate to severe depression increases risk of heart failure by 40%

Men with long-term HIV infections at higher risk of developing plaque in their coronary arteries

Amgen reports positive findings from AMG 145 Phase 3 studies in patients at risk for cardiovascular disease

Mechanical circulatory assist device may have untapped potential in heart surgery patients, say physicians

Study of astronauts show heart becomes more spherical when exposed to microgravity in space

Celiac disease people may have near two-fold increased risk of coronary artery disease

Women who have 4 or more live births more likely to show early signs of heart disease

New finding reinforces importance of developing healthy eating habits early in life

Findings underscore importance of universal pediatric cholesterol screening

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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