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Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

The advent of targeted drugs for a specific type of breast cancer - HER2 positive - has dramatically improved survival rates for women with the disease. But a study led by researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center reveals low rates of use of a targeted drug among older women with early-stage breast cancer of this type, and even lower rates for older black women.

13 Apr 2016

Inserm study reveals potential of secondary system to improve heart function

Heart failure affects over one million people in France. Although the blood system is the first to have been explored for the purpose of improving heart function, a study by Inserm has revealed the potential of a secondary system that had previously received scant attention.

13 Apr 2016

AstraZeneca, MedImmune to present new clinical trial and scientific data on lung cancer treatments at ELCC 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will report new clinical trial and scientific data from their industry-leading lung cancer franchise of marketed and pipeline medicines at the European Lung Cancer Conference in Geneva, Switzerland, 13 -16 April 2016.

11 Apr 2016

Physical, mental training may improve health of young schizophrenia patients

In as little as a few months, antipsychotic medications can tame the delusions and hallucinations that characterize schizophrenia. But the medications do little to reverse the less familiar brain-based problems that accompany the illness.

7 Apr 2016

Study shows epidermal growth factor negatively regulates shedding of epithelial cells

The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. Altered shedding is associated with multiple disorders, ranging from inflammatory bowel disease (IBD) to colorectal cancer.

6 Apr 2016

Scientists successfully turn off misbehaving protein that fuels growth of triple-negative breast cancer

Working with human breast cancer cells, a team of scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have successfully turned off a misbehaving protein that fuels the growth of a particularly aggressive, drug-resistant form of the disease known as triple-negative breast cancer.

5 Apr 2016

Study identifies genetic differences in kidney tumors of African-Americans

A University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared with whites.

26 Mar 2016

Novel mechanism can suppress blood vessel leakage, reduce tumour spread in mice

Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated.

24 Mar 2016

SLU researchers discover compound that disrupts fibrotic process

Saint Louis University researchers have found that a type of compound that disrupts the process that causes fibrosis (scarring) in the lungs and liver also shows promise in preventing and treating fibrosis in yet another organ, the pancreas. The research was conducted in an animal model.

23 Mar 2016

Ovarian serous cancer patients with overexpression of HER4 protein less likely respond to chemotherapy

Moffitt Cancer Center researchers discovered that patients with ovarian serous cancer and an overexpression of the HER4 protein are less likely to respond to chemotherapy and have a lower rate of survival.

21 Mar 2016

New study reveals why certain cancer drugs not always effective in halting tumor growth

New cancer drugs allow doctors to tailor treatment based on the genetic profile of a patient's tumor. However, these drugs don't work at all in some patients, and they lose their effectiveness in others.

17 Mar 2016

New method to harvest stem cells reduces side effects for donors

Australian scientists have developed a new method for harvesting stem cells, which is less invasive and reduces side effects for donors.

16 Mar 2016

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New research from Boston Children's Hospital could potentially change how doctors approach two blinding diseases: 'Wet' age-related macular degeneration (AMD), the leading cause of blindness in the elderly, and macular telangiectasia (MacTel).

15 Mar 2016

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Researchers report photoimmunotherapy to be effective against elusive gastric cancer cells following transduction with the gene that expresses the extracellular domain protein of HER2. The results are published in the journal Small Molecule Therapeutics in February 2016.

15 Mar 2016

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Researchers have shown for the first time that it is possible to use a multi-gene test to identify patients with early breast cancer who can be spared chemotherapy and who will still be alive and well five years after diagnosis.

11 Mar 2016

New drug combination treatment makes breast cancer tumours disappear in just 11 days

Approximately a quarter of women with HER2 positive breast cancer, who were treated with a combination of the targeted drugs lapatinib and trastuzumab before surgery and chemotherapy, saw their tumours shrink significantly or even disappear, according to results from a clinical trial.

11 Mar 2016

Researchers reveal how butterfly disease patients develop cutaneous squamous cell carcinomas

Fragile skin that blisters easily: 90 percent of the patients that suffer from the skin condition recessive dystrophic epidermolysis bullosa (RDEB) develop rapidly progressing cutaneous squamous cell carcinomas, a type of skin cancer, by the age of 55. 80 percent of these patients will die due to metastasis within five years after the cancer has been first detected.

11 Mar 2016

CWRU researcher to customize tobacco mosaic virus to treat human cancers

A Case Western Reserve University researcher has been awarded more than $3 million in federal and foundation grants to turn common plant viruses into cancer sleuths and search-and-destroy emissaries.

10 Mar 2016

UC San Diego physicians develop potential new therapy for critical limb ischemia

Bioengineers and physicians at the University of California, San Diego have developed a potential new therapy for critical limb ischemia, a condition that causes extremely poor circulation in the limbs and leads to an estimated 230,000 amputations every year in North America and Europe alone to prevent the spread of infection and tissue death.

9 Mar 2016

New FDA approval expands use of AstraZeneca's Faslodex for women with HR+, HER2- metastatic breast cancer

AstraZeneca today announced that the US Food and Drug Administration has approved a new indication in the US, expanding the use of Faslodex (fulvestrant) to include use in combination with Ibrance (palbociclib).

7 Mar 2016

Growth Factor News and Research

Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

Inserm study reveals potential of secondary system to improve heart function

AstraZeneca, MedImmune to present new clinical trial and scientific data on lung cancer treatments at ELCC 2016

Physical, mental training may improve health of young schizophrenia patients

Study shows epidermal growth factor negatively regulates shedding of epithelial cells

Scientists successfully turn off misbehaving protein that fuels growth of triple-negative breast cancer

Study identifies genetic differences in kidney tumors of African-Americans

Novel mechanism can suppress blood vessel leakage, reduce tumour spread in mice

SLU researchers discover compound that disrupts fibrotic process

Ovarian serous cancer patients with overexpression of HER4 protein less likely respond to chemotherapy

New study reveals why certain cancer drugs not always effective in halting tumor growth

New method to harvest stem cells reduces side effects for donors

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

New drug combination treatment makes breast cancer tumours disappear in just 11 days

Researchers reveal how butterfly disease patients develop cutaneous squamous cell carcinomas

CWRU researcher to customize tobacco mosaic virus to treat human cancers

UC San Diego physicians develop potential new therapy for critical limb ischemia

New FDA approval expands use of AstraZeneca's Faslodex for women with HR+, HER2- metastatic breast cancer

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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