Neurodegenerative Diseases News and Research

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Experts address the global burden of brain diseases

Think Brain Health - a policy, clinical and research challenge, a virtual meeting featuring expert speakers in the field of neurodegenerative diseases, addressed current and future opportunities to help everyone achieve good brain health.

3 Dec 2020

Patch-seq technique helps depict the variation of neural cells in the brain

The tree of life describes the evolution of life and seeks to define the relationships between species. Likewise, the tree of cell types aims to organize cells in the brain into groups and describe their relationships to each other.

3 Dec 2020

Novel ALS study effectively visualizes neuroinflammation

A novel ALS (amyotrophic lateral sclerosis) study has pooled data from multiple sites to effectively visualize neuroinflammation, which is key to developing drugs to treat the disease.

2 Dec 2020

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

The onset of any physical exercise program causes muscle pain that can hinder movements as simple as getting up from a sofa. With time and a little persistence, the muscles become accustomed to the effort, developing more strength and endurance.

1 Dec 2020

Study may help to better understand the pathological process involved in brain diseases

A team of researchers at the Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer's disease and several other neurodegenerative disorders.

1 Dec 2020

FAU receives $675,000 grant to improve social engagement in older population

Vibrant social relationships are a critical component of healthy aging. Strong relationships provide emotional support and well-being, promote brain health, and can even slow the progression of neurodegenerative diseases.

1 Dec 2020

Inflammation produced by bacterial infection 'alerts' the brain stem cells

The study, directed by Isabel Fariñas and published in the November digital edition of the journal Cell Stem Cell, reveals that the inflammation produced by a bacterial infection 'alerts' the brain stem cells and prepares their activation for the production of new neurons.

27 Nov 2020

Study finds how the brain 're-wires' after neurological disease

Trinity College researchers are studying how the brain re-wires itself in neurological disease.

24 Nov 2020

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late onset, such as neurodegenerative diseases.

23 Nov 2020

Build-up of cellular 'trash' in the brain can cause neurodegeneration, death

A little mess never killed anyone, right? Wrong. Researchers at Tokyo Medical and Dental University (TMDU) have recently shown that a build-up of cellular "trash" in the brain can actually cause neurodegeneration, and even death.

19 Nov 2020

Alzheimer's study shows tau protein changes according to dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

Fatal chain reaction in Alzheimer's disease starts much earlier than commonly assumed

Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain.

18 Nov 2020

Active bilingualism protects against cognitive decline

In addition to enabling us to communicate with others, languages are our instrument for conveying our thoughts, identity, knowledge, and how we see and understand the world.

16 Nov 2020

Study confirms link between gut microbiota and Alzheimer's disease

Alzheimer's disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole.

16 Nov 2020

Machine-learning based analysis of mitochondria interaction networks to advance PD diagnosis

In a new study led by the Immune Systems Biology research group of the LIH Department of Infection and Immunity, researchers adopted a holistic machine-learning approach to elucidate how the interactions between neuronal mitochondria can serve as a powerful tool to distinguish nerve cells from Parkinson’s patients from those belonging to healthy subjects, thereby providing new insights in the pathogenesis, diagnosis and treatment of this neurodegenerative disorder.

12 Nov 2020

Biologists investigate how molecular chaperones dissolve protein aggregates linked to Parkinson's

In many neurodegenerative diseases like Parkinson's, protein aggregates form in the brain and are assumed to contribute to neuronal cell death.

11 Nov 2020

MU researcher develops procedures for defining the preclinical stages of Alzheimer's disease

Both of Andrew Kiselica's grandfathers developed dementia when he was in graduate school. As Kiselica was going through neuropsychology training in graduate school, he saw his mother's father become unable to walk or speak due to severe dementia.

11 Nov 2020

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Microglia -- the brain's immune cells -- play a primary role in removing cellular debris from the brain. According to a recent study by a Nagoya University-led research team in Japan, another kind of brain cell, called astrocyte, is also involved in removing debris as a backup to microglia.

11 Nov 2020

Psychological factors are linked to incorrect fall risk perception in dementia patients

Dementia is associated with an impaired self-perception with potentially harmful consequences for health status and clinical risk classification in this patient group with an extraordinary high risk of falling.

11 Nov 2020

Study: Optogenetic stimulation of circuit improves symptomatology of Huntington's disease

Huntington's disease is an hereditary neurodegenerative disease featured by alterations in movement, cognitive deficiency and psychiatric disorders resulting from the degeneration of neurons in the striatum nucleus of the brain.

11 Nov 2020

Neurodegenerative Diseases News and Research

Experts address the global burden of brain diseases

Patch-seq technique helps depict the variation of neural cells in the brain

Novel ALS study effectively visualizes neuroinflammation

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

Study may help to better understand the pathological process involved in brain diseases

FAU receives $675,000 grant to improve social engagement in older population

Inflammation produced by bacterial infection 'alerts' the brain stem cells

Study finds how the brain 're-wires' after neurological disease

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Build-up of cellular 'trash' in the brain can cause neurodegeneration, death

Alzheimer's study shows tau protein changes according to dementia stage

Fatal chain reaction in Alzheimer's disease starts much earlier than commonly assumed

Active bilingualism protects against cognitive decline

Study confirms link between gut microbiota and Alzheimer's disease

Machine-learning based analysis of mitochondria interaction networks to advance PD diagnosis

Biologists investigate how molecular chaperones dissolve protein aggregates linked to Parkinson's

MU researcher develops procedures for defining the preclinical stages of Alzheimer's disease

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Psychological factors are linked to incorrect fall risk perception in dementia patients

Study: Optogenetic stimulation of circuit improves symptomatology of Huntington's disease

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