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Breast cancer drug shows promise in treating young infants with PIK3CA-related overgrowth spectrum

PIK3CA-related overgrowth spectrum (PROS) is a group of rare, incurable disorders caused by mutations in the PIK3CA gene that result in the malformation and overgrowth of various parts of the body.

26 Jan 2022

AMSBIO Expands EU Operations

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From AMS Biotechnology 26 Jan 2022

Optical imaging reveals how cancer cells hijack metabolic activity to fuel pancreatic tumor growth

Pancreatic cancer is a rare, yet elusive and deadly cancer, with a five-year survival rate of about 10%. If the cancer has metastasized, that rate lowers to 3%. And treatment options are extremely limited.

22 Jan 2022

Exploring the viral dynamics of SARS-CoV-2 Omicron variant

In a new study, researchers posted findings in which they investigated the viral dynamics of the SARS-CoV-2 Omicron variant.

18 Jan 2022

Officials struggle to regulate pop-up covid testing sites — and warn patients to beware

In recent months, mobile covid-19 testing tents and vans have sprouted on urban sidewalks and street curbs as demand has skyrocketed in response to the rapid spread of the omicron variant.

18 Jan 2022

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Researchers determine the driving factors for disease severity and death due to COVID-19.

17 Jan 2022

Naïve T cells suggested as critical to low mortality of children with COVID-19

A new study discusses how naïve T cells may contribute to lower mortality rates seen in children with COVID-19.

14 Jan 2022

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular "crosstalk" in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.

12 Jan 2022

New insights into molecular mechanisms that underpin the body's natural defenses against skin cancer

A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body's natural defenses against the development of skin cancer.

11 Jan 2022

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

A new preprint examines the extent of protection offered by T cell responses to primary vaccination and/or natural infection with the virus.

11 Jan 2022

COVID-19 symptoms found to vary in different immune contexts

In a new study, researchers studied the kinetics of host response to SARS-CoV-2 infection in a Syrian hamster model, tracking disease pathology, viral loads, antibody responses, and inflammatory cytokine production in multiple organs.

11 Jan 2022

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

History of SARS-CoV-2 infection affects longitudinal responses to BNT162b2 vaccine

In a recently published article in the journal Cell Reports, scientists have demonstrated that individuals with or without a history of coronavirus disease 2019 (COVID-19) exhibit differential humoral and cellular immune responses 14 days after receiving mRNA-based COVID-19 vaccine developed by Pfizer/BioNTech. However, at a later time point, the responses become comparable between the two groups.

9 Jan 2022

Model suggests feasibility of shorter COVID-19 isolation period with minimal risk

Researchers set up a model that included parameters such as the infectiousness of the individual, and lateral flow testing, in order to assess the effectiveness of test-to-release policies as compared to those with fixed-duration isolation mandates

7 Jan 2022

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

The Wistar Institute announces the initiation of a Phase 2 clinical study of VK-2019 in patients with advanced Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and lymphoma.

5 Jan 2022

Scientists find that having one kind of autoimmune disease can lead to another

Researchers at the University of Colorado Anschutz Medical Campus have discovered that having one kind of autoimmune disease can lead to another.

4 Jan 2022

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

3 Jan 2022

Olfactory receptor gene may play a role in breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital (MGH) have found.

3 Jan 2022

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

A new study used in silico approaches for designing a next-generation CD40-targeting vaccine, CD40.

31 Dec 2021

Intestinal organoids used to explain why bats infected with viruses do not succumb to diseases

Experiments attempting to explain why bats can be infected with many viruses at a time without succumbing to diseases such as COVID-19 - knowledge that could help us to reduce the threat to humans of infectious disease - have struggled until now with the fact that live wild bats make poor research subjects.

30 Dec 2021

Proliferation News and Research

Breast cancer drug shows promise in treating young infants with PIK3CA-related overgrowth spectrum

AMSBIO Expands EU Operations

Optical imaging reveals how cancer cells hijack metabolic activity to fuel pancreatic tumor growth

Exploring the viral dynamics of SARS-CoV-2 Omicron variant

Officials struggle to regulate pop-up covid testing sites — and warn patients to beware

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Naïve T cells suggested as critical to low mortality of children with COVID-19

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

New insights into molecular mechanisms that underpin the body's natural defenses against skin cancer

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

COVID-19 symptoms found to vary in different immune contexts

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

History of SARS-CoV-2 infection affects longitudinal responses to BNT162b2 vaccine

Model suggests feasibility of shorter COVID-19 isolation period with minimal risk

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

Scientists find that having one kind of autoimmune disease can lead to another

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Olfactory receptor gene may play a role in breast cancer metastasis to the brain

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

Intestinal organoids used to explain why bats infected with viruses do not succumb to diseases

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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