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HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

Fragmented care does not impact survival in rare sarcoma cases

Fragmented care - receiving medical treatment at more than one facility - has been associated with both positive and negative outcomes for cancer patients depending on a number of factors such as cancer type and treatment venue.

13 May 2025

New treatment approach boosts survival rates for patients with aggressive, inherited breast cancers

A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers, according to Cambridge researchers.

13 May 2025

Pentoxifylline offers no survival benefit for severe alcohol-associated hepatitis

Severe alcohol-associated hepatitis (sAH) remains a highly lethal condition with limited therapeutic options. Characterized by rapid liver decompensation, sAH is often accompanied by acute kidney injury (AKI), a complication that substantially worsens prognosis.

13 May 2025

Testosterone use not linked to increased gynecological cancer risk in early years

Transmasculine and gender-diverse individuals who use testosterone are not at increased risk of gynecological cancer in the first years of hormone therapy.

12 May 2025

Study shows cardiovascular benefits of GLP-1RAs in patients following bariatric surgery

Medications like semaglutide and liraglutide may help to reduce the risk for heart attacks, strokes, and other major adverse cardiovascular events (MACE) as well as death in adults with obesity and diabetes following bariatric surgery who did not achieve sufficient weight loss and diabetes control, according to new research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain.

12 May 2025

Large language models help predict epileptogenic zones for surgery

Epilepsy, one of the most common neurological disorders characterized by recurrent seizures, affects over 70 million people worldwide.

12 May 2025

Hearing aids may help older adults combat social isolation

Providing hearing aids and advice on their use may preserve social connections that often wane as we age, a new study shows.

12 May 2025

City of Hope opens largest outpatient facility to enhance cancer care

As advances in early detection and treatment transform cancer into a chronic disease, City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, opens its largest outpatient facility among its network of 38 U.S. locations.

12 May 2025

An Arm and a Leg: A health policy veteran puts 2025 in perspective

News has been coming out of Washington, D.C., since the start of the second Donald Trump administration like water out of a fire hose. It can feel impossible to stay on top of all the changes.

12 May 2025

GLP-1RAs show added protection against cancer beyond weight reduction

New research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) and published in the journal eClinicalMedicine finds that first generation weight-loss medications like liraglutide and exenatide appear to show anti-cancer benefits beyond weight loss.

11 May 2025

Woman with rare genetic disorder delivers healthy baby after complex pregnancy

When Jessica Johnson, 36, began to experience labored breathing and heart palpitations, she quickly made an appointment to see a cardiologist.

11 May 2025

Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

Gum disease bacterium linked to increased risk of atrial fibrillation

Tempted to skip the floss? Your heart might thank you if you don't. A new study from Hiroshima University (HU) finds that the gum disease bacterium Porphyromonas gingivalis (P. gingivalis) can slip into the bloodstream and infiltrate the heart.

10 May 2025

MicroRNA breakthrough offers hope for dental bone regeneration

Dental caries, or tooth decay, is a common oral health condition that often causes significant pain and discomfort and may even lead to tooth loss.

8 May 2025

Study reveals regional risk factors driving heart disease in Asia and Oceania

A new study puts the spotlight on the rising burden of ischemic heart disease across Southeast Asia, East Asia and Oceania, and calls for localized, equity-focused interventions in these regions.

8 May 2025

AI tool uses facial images to predict biological age and cancer survival

Eyes may be the window to the soul, but a person's biological age could be reflected in their facial characteristics. Investigators from Mass General Brigham developed a deep learning algorithm called FaceAge that uses a photo of a person's face to predict biological age and survival outcomes for patients with cancer.

8 May 2025