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Molnupiravir does not induce resistance mutations in SARS-CoV-2 genome

A new study has pointed out that Molnupiravir treatment increases the ratio of transition to transversion mutations in COVID-19 patients and that the treatment does not appear to induce resistance mutations in the SARS-CoV-2 genome.

19 Jul 2022

New Oxford study examines the effectiveness of pharmacological treatments for insomnia

Two drugs, eszopiclone and lemborexant - both not currently licenced for the treatment of insomnia in the UK - were shown to perform better than others, both in the acute and long-term treatment of insomnia in adults, according to a new Oxford study exploring the pharmacological management of insomnia.

19 Jul 2022

Overstrict salt intake restriction could harm patients with heart failure with preserved ejection

Restricting salt intake is considered a key component of heart failure treatment, but restricting it too much may actually worsen the outcomes for people with a common form of the condition, suggests research published online in the journal Heart.

19 Jul 2022

Could Vitamin B6 Reduce Anxiety and Depression?

In this interview, we speak to Dr. David Field about his latest research into anxiety and depression and whether vitamin B6 supplements could help to reduce it.

19 Jul 2022

Should siRNA-based antivirals be added to the COVID toolbox?

A recent study reviewed the existing treatment modalities, including vaccines and antivirals, for SARS-CoV-2 infection.

19 Jul 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application to the European Medicines Agency for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 19 Jul 2022

Prostaglandin E1 could enhance the safety of ECMO

In case of heart and/or lung failure, an ECMO machine can be used to maintain organ function for days or even weeks.

18 Jul 2022

Sore throat lozenges and sprays provide only a small reduction in throat pain

It's hard to get through a winter without suffering sore throat, but luckily they normally get better within a few days.

15 Jul 2022

Adding erythropoietin to cooling therapy shows no added benefits for newborns with birth asphyxia

Adding erythropoietin to cooling therapy for term newborns with birth asphyxia has no benefit over cooling therapy alone, a study published today in the New England Journal of Medicine.

14 Jul 2022

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

A drug used in the clinical treatment of angina symptoms also has an anti-inflammatory effect and reduces atherosclerotic plaques in blood vessels - thereby reducing the risk of heart attack or stroke.

14 Jul 2022

The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients

Scientists assessed the potential of tixagevimab–cilgavimab for treating hospitalized SARS-CoV-2 patients.

13 Jul 2022

Monoclonal antibody treatment taken by hospitalized COVID-19 patients reduces mortality

A monoclonal antibody treatment taken by patients hospitalized with COVID-19 did not improve recovery time but did reduce deaths, according to a study published July 8 in The Lancet Respiratory Medicine.

8 Jul 2022

Study reports how opioids cause gastric inflammation

Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation.

6 Jul 2022

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

A new study assessed both placebo and vaccine recipients in the mRNA-1273 (Moderna) phase 3 clinical trial who were infected with SARS-CoV-2 during the blinded, placebo-controlled trial phase.

6 Jul 2022

Study measures changes in the brain's response to threat following non-invasive vagus nerve stimulation

A first-of-its-kind study published recently in the journal "Brain Stimulation" measures changes in the human brain's response to a perceived threat following non-invasive stimulation of the nervous system via the vagus nerve

6 Jul 2022

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Convalescent plasma, widely given to severely ill patients hospitalized with COVID-19 during the pandemic, does not improve their ability to survive or recover, according to a national clinical trial led by Vanderbilt University Medical Center and published in the journal CHEST.

5 Jul 2022

Risk of eczema in babies could be lowered by taking vitamin D supplements during pregnancy

Taking Vitamin D supplements during pregnancy could substantially reduce the chances of babies up to a year old suffering from atopic eczema, according to a new study by University of Southampton researchers.

5 Jul 2022

Probiotics do not improve unhealthy vaginal flora, study shows

Pregnancy chances in IVF can be affected by many factors including the type of bacteria which naturally colonize the reproductive tract.

4 Jul 2022

Bladder cancer patients with ctDNA positivity respond very well to treatment with atezolizumab

Researchers who treated a group of post-surgery bladder cancer patients with the immunotherapy drug atezolizumab have found that patients whose blood contained circulating tumour DNA (ctDNA), responded very well to the treatment.

3 Jul 2022

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

In a recent article posted to the bioRxiv* preprint server, researchers at Rutgers, the State University of New Jersey, the University of South Florida, and the Catholic University of America demonstrated that the natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) mutations result in nirmatrelvir resistance.

30 Jun 2022

Placebo News and Research

Molnupiravir does not induce resistance mutations in SARS-CoV-2 genome

New Oxford study examines the effectiveness of pharmacological treatments for insomnia

Overstrict salt intake restriction could harm patients with heart failure with preserved ejection

Could Vitamin B6 Reduce Anxiety and Depression?

Should siRNA-based antivirals be added to the COVID toolbox?

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

Prostaglandin E1 could enhance the safety of ECMO

Sore throat lozenges and sprays provide only a small reduction in throat pain

Adding erythropoietin to cooling therapy shows no added benefits for newborns with birth asphyxia

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients

Monoclonal antibody treatment taken by hospitalized COVID-19 patients reduces mortality

Study reports how opioids cause gastric inflammation

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

Study measures changes in the brain's response to threat following non-invasive vagus nerve stimulation

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Risk of eczema in babies could be lowered by taking vitamin D supplements during pregnancy

Probiotics do not improve unhealthy vaginal flora, study shows

Bladder cancer patients with ctDNA positivity respond very well to treatment with atezolizumab

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

Industry Focus eBook - Cell biology (5th edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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