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USC’s new center aims to address unmet needs in neurodegenerative diseases of the eye and brain

Could a new paradigm in digital health treat blinding disorders and possibly also be a conduit for treating other parts of the brain? A multi-disciplinary team of world-renowned researchers at USC are exploring this exciting possibility.

28 Jan 2022

Strict COVID-19 lockdown policies helped reduce air pollution levels and death rates in Europe

Strict COVID-19 lockdown policies such as workplace closures in European cities reduced levels of air pollution and the number of associated deaths, according to new estimates published in Nature's Scientific Reports.

27 Jan 2022

Study demonstrates differential alternative splicing in betacoronaviruses

A new study investigates whether the proportion of ribosomal genes displaying differential gene expression and differential alternative splicing differed between three betacoronaviruses and six other viruses and bacteria.

26 Jan 2022

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

26 Jan 2022

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

In a recent study posted to the bioRxiv* preprint server, researchers evaluated the mechanism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated inflammatory marker interferon (IFN) repression in hosts.

25 Jan 2022

New therapeutic approach offers hope to treat obesity and related metabolic disorders

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new therapeutic approach to obesity and related metabolic disorders that in laboratory experiments demonstrated a significant reduction in body fat, body weight, and improvement in the blood markers that accompany these disorders.

25 Jan 2022

How artificial intelligence is poised to reshape medicine

In a recent review published in the journal of Nature Medicine, researchers discussed the results of a two-year weekly effort to track and communicate significant developments in medical (artificial intelligence) AI. They included prospective studies as well as developments in medical image analysis that have narrowed the gap between research and implementation.

24 Jan 2022

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

24 Jan 2022

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

In a recent study posted to the bioRxiv* preprint server, researchers developed a novel bioinformatic algorithm to predict host cleavage targets of the SARS-CoV-2 3C-like protease (3CLPro).

23 Jan 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

Pilot human trial uses new falloposcope device to capture images of fallopian tubes

Due to a lack of effective screening and diagnostic tools, more than three-fourths of ovarian cancer cases are not found until the cancer is in an advanced stage.

22 Jan 2022

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

20 Jan 2022

Biden administration’s rapid-test rollout doesn’t easily reach those who need it most

In the past week, the Biden administration launched two programs that aim to get rapid covid tests into the hands of every American. But the design of both efforts disadvantages people who already face the greatest barriers to testing.

20 Jan 2022

‘Heart’ of Little Shell: Newest federally recognized tribe to open first clinic

Louella Fredrickson has long created workarounds to fill gaps in the spotty medical care available to her as a member of the Little Shell Tribe of Chippewa Indians of Montana.

20 Jan 2022

Impact of COVID-19 on male and female reproductive health

A new review article investigated the relation between SARS-CoV-2 infection and reproductive health.

19 Jan 2022

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Chinese scientists recently reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell death regulator (LCDR) in tumor survival, providing a potential diagnostic and therapeutic target for lung cancer.

18 Jan 2022

Can meal times affect your risk of glucose intolerance?

In this interview, we speak to Dr. Frank Scheer and Dr. Sarah Chellappa about their latest research that investigated the effect meal times has on glucose intolerance.

18 Jan 2022

Topical antiseptic Acriflavine inhibits SARS-CoV-2 and other betacoronaviruses

A new study, published in the journal Cell Chemical Biology, has reported the discovery of acriflavine (ACF), an effective inhibitor of SARS-CoV-2. This drug is a mixture of trypaflavines (3,6-diamino-10-methylacridinium chloride and 3,6-diamino-3-methylacridinium chloride) and proflavine (3,6-diaminoacridine).

16 Jan 2022

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

In this study, researchers described the effect of significant changes of small RNAs in the post-transcriptional regulatory network.

13 Jan 2022

The unique T cell response elicited by SARS-CoV-2 during a primary immune response by infection and vaccination

The distinctive characteristics of the T cell response generated by SARS-CoV-2 infection and vaccination and the relationship to CCCoVs and VOC was explored in a review published in Frontiers in Medicine.

13 Jan 2022

Translation News and Research

USC’s new center aims to address unmet needs in neurodegenerative diseases of the eye and brain

Strict COVID-19 lockdown policies helped reduce air pollution levels and death rates in Europe

Study demonstrates differential alternative splicing in betacoronaviruses

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

New therapeutic approach offers hope to treat obesity and related metabolic disorders

How artificial intelligence is poised to reshape medicine

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

Genetic marker linked to higher risk of death in COVID-19 patients

Pilot human trial uses new falloposcope device to capture images of fallopian tubes

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Biden administration’s rapid-test rollout doesn’t easily reach those who need it most

‘Heart’ of Little Shell: Newest federally recognized tribe to open first clinic

Impact of COVID-19 on male and female reproductive health

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Can meal times affect your risk of glucose intolerance?

Topical antiseptic Acriflavine inhibits SARS-CoV-2 and other betacoronaviruses

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

The unique T cell response elicited by SARS-CoV-2 during a primary immune response by infection and vaccination

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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