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Schistosome stem cells could explain how the worms survive for so many years

The parasites that cause schistosomiasis, one of the most common parasitic infections in the world, are notoriously long-lived. Researchers have now found stem cells inside the parasite that can regenerate worn-down organs, which may help explain how they can live for years or even decades inside their host.

24 Feb 2013

Janssen submits simeprevir regulatory application in Japan to treat HCV

Medivir AB today announced that its partner Janssen now has submitted a regulatory application to the Japanese Ministry of Health & Welfare authorities seeking approval for simeprevir, administered with pegylated interferon (Peg-IFN) and ribavirin (RBV) for the treatment of genotype 1 chronic hepatitis C patients who are treatment naïve, prior non responders or relapsed following treatment with Peg-IFN with or without RBV.

22 Feb 2013

Targeting CSF1R with selective inhibitors could help Alzheimer's

Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases.

22 Feb 2013

Craniofacial surgeons recommend steps to reduce risk of pneumonitis from povidone-iodine

A routine step in preparing for cleft palate surgery in a child led to an unusual-but not unprecedented-case of lung inflammation (pneumonitis), according to a report in the The Journal of Craniofacial Surgery. The journal, edited by Mutaz B. Habal, MD, FRCSC, is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

22 Feb 2013

Imatinib can relieve and slow down progression of multiple sclerosis

A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study published in PLOS ONE.

21 Feb 2013

Omega-3 emulsions can decrease brain tissue damage following stroke

Triglyceride lipid emulsions rich in an omega-3 fatty acid injected within a few hours of an ischemic stroke can decrease the amount of damaged brain tissue by 50 percent or more in mice, reports a new study by researchers at Columbia University Medical Center.

21 Feb 2013

Tips to help reduce dry eyes

Some of the last days of winter can be among the worst for your eyes. Winter may be slowly giving way to spring, but the remaining cold days of the season can cause plenty of trouble for the eyes—trouble that is largely avoidable, says a Vanderbilt Eye Institute ophthalmologist.

21 Feb 2013

Immune Pharmaceuticals commences Phase II study with bertilimumab to treat ulcerative colitis

Immune Pharmaceuticals Ltd., a privately held Israeli company, and EpiCept Corporation announced today that Immune is initiating, following authorization from Israeli health authorities, a Phase II double-blind placebo controlled study with its lead drug, bertilimumab, in patients with moderate-to-severe ulcerative colitis.

21 Feb 2013

UCB seeks FDA and EMA marketing authorization for Cimzia to treat active psoriatic arthritis

UCB announced today two new regulatory filings with the US Food and Drug Administration (FDA) and with the European Medicines Agency (EMA) to extend the marketing authorization for Cimzia (certolizumab pegol) for the treatment of adult patients with active psoriatic arthritis (PsA) and for adult patients with active axial spondyloarthritis (axSpA).

20 Feb 2013

Resistant starch kills pre-cancerous cells and reduces inflammation

As the name suggests, you can't digest resistant starch so it ends up in the bowel in pretty much the same form it entered your mouth. As unlovely as that seems, once in the bowel this resistant starch does some important things, including decreasing bowel pH and transit time, and increasing the production of short-chain fatty acids. These effects promote the growth of good bugs while keeping bad bugs at bay.

20 Feb 2013

Targeting p38alpha MAPK isoform can help treat CNS inflammatory diseases

A study by a leading Alzheimer's researcher at the University of Kentucky provides new evidence that will help researchers home in on the molecular mechanisms involved in inflammation of the central nervous system (CNS) and aid drug-development strategies for treating inflammatory neurological diseases.

20 Feb 2013

Study establishes possible link between high-fat diets and ADHD, learning disabilities

A University of Illinois study has established a possible link between high-fat diets and such childhood brain-based conditions as attention deficit hyperactivity disorder (ADHD) and memory-dependent learning disabilities.

19 Feb 2013

Loyola proposes new subspecialty to diagnose and treat patients with depression, heart disease

A Loyola University Medical Center psychiatrist is proposing a new subspecialty to diagnose and treat patients who suffer both depression and heart disease. He's calling it "Psychocardiology."

19 Feb 2013

Severe childhood asthma blood test hopes dashed

Blood eosinophil counts do not reliably reflect airway eosinophil concentrations in children with severe, therapy-resistant asthma, and therefore cannot be used to make therapeutic decisions, researchers report.

19 Feb 2013

Piroxicam ultrasound combination optimal for knee osteoarthritis

Phonophoresis of the non steroidal anti-inflammatory drug piroxicam with ultrasound is more effective than ultrasound alone for improving pain and other symptoms of mild-to-moderate knee osteoarthritis, show study findings.

19 Feb 2013

Eosinophilic inflammation of the esophagus relieved by diet

A diet that eliminates six food types has proved effective at inducing remission of eosinophilic esophagitis in adults, report researchers.

18 Feb 2013

Interleukin-10 levels predict otitis media culprit

Research shows that high serum levels of interleukin-10 indicate that the likely cause of acute otitis media is infection with Streptococcus pneumoniae, as opposed to Haemophilus influenzae or Moraxella catarrhalis.

18 Feb 2013

Study describes pharmacological action of TZDs directly on pancreas

A scientific study published on the journal Diabetes, edited by the American Diabetes Association, describes for the first time the pharmacological action of thiazolidinediones (TZDs) —anti-diabetic drugs— directly on pancreas, the organ which produces insulin.

18 Feb 2013

Two studies discover new enzyme that acts as a sensor of innate immunity

Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.

16 Feb 2013

IKBKE gene plays a key role in tobacco-induced lung cancer

Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune response.

16 Feb 2013