Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

New Parkinson's disease research points to serotonin

For most people with Parkinson's disease, the only relief from the tremors, rigidity and impaired movement associated with the progressive loss of their motor skills is a drug called L-DOPA. But as the disease progresses, L-DOPA can cause prominent side effects that counteract its effectiveness.

4 Feb 2008

Antidepressants might be worthless for treating low back pain

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

30 Jan 2008

No clear evidence that antidepressants assist in the management of chronic low back pain

Doctors commonly prescribe antidepressants for patients with low back pain for three main reasons; to relieve pain; reduce mild depression and improve a person's mood; and improve sleep.

24 Jan 2008

Genetic difference predicts antidepressant response

Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant drugs.

24 Jan 2008

Duloxetine does not relieve painful physical symptoms in depression

An analysis of the data which are available, published in the European Journal Psychotherapy and Psychosomatics, discloses that the maker's claims are not warranted.

22 Jan 2008

Selective publication means unfavorable drug studies rarely get published

A new report claims that almost a third of the research done on antidepressant drugs is never published in medical literature and most of those unpublished reports are unfavorable.

20 Jan 2008

Selective reporting of antidepressant trials exaggerates drug effectiveness

Selective publication in reporting results of antidepressant trials exaggerates the effectiveness of the drugs, according to a report in the January 17 issue of the New England Journal of Medicine.

17 Jan 2008

Does it help to continue antidepressant drug treatment for preventing recurrence in depression?

Apparently not very much, according to a study by Dutch investigators published in the Jan 2008 issue of Psychotherapy and Psychosomatics.

17 Jan 2008

FDA warnings appeared to effectively increase perception of risks involved with antidepressant treatment

U.S. Food and Drug Administration warnings regarding the risk of suicidal thoughts and behaviors in children and adolescents taking antidepressants appear to have had modest and targeted effects on the intended populations, according to a report in the January issue of Archives of General Psychiatry.

8 Jan 2008

How might lack of light cause depression?

People troubled by depression usually experience their dark moods in an on-again, off-again fashion.

18 Dec 2007

Venlafaxine extended-release effective for patients with major depression

Major depressive disorder (MDD) is the most common major mental illness, afflicting almost one in five individuals.

13 Dec 2007

Human hormone shows potential as new antidepressant agent

Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the December 1st issue of Biological Psychiatry explains.

12 Dec 2007

New studies on brain and behavior from the world's leading scientists

The 2007 American College of Neuropsychopharmacology Annual Meeting will feature hundreds of new studies on brain and behavior from the world's leading scientists.

10 Dec 2007

Psychotherapy useful in treating PTSD in early stages

When treated within a month, survivors of a psychologically traumatic event improved significantly with psychotherapy, according to a new study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

New strategy for developing antidepressants

Researchers may be able to develop an antidepressant which takes effect almost immediately by directly targeting novel molecules in the brain instead of taking a less direct route, which can lead to longer times for medication to take effect, according to a new study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

Depression nearly triples the risk of death following a heart attack

...even when accounting for other heart attack risk factors, according to research presented at the American College of Neuropsychopharmacology (ACNP) annual meeting, which showed that among 360 depressed, post myocardial infarction patients followed for more than six years, those who did not recover from their depression in the first six months were more than twice as likely to die.

10 Dec 2007