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CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Patients with multiple myeloma treated with idecabtagene vicleucel, known as "ide-cel," a chimeric antigen receptor (CAR) T-cell therapy, had no difference in overall survival outcomes regardless of race and ethnicity, according to a study published in Blood Advances.

19 Oct 2023

Turning brain immune cells into neurons restores brain function after stroke-like injury in mice

Researchers at Kyushu University have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice.

18 Oct 2023

Surgery to straighten a crooked septum more effective than nasal sprays, trial suggests

Surgery to straighten a crooked septum (the thin wall of bone and cartilage dividing the space between the two nostrils) is more effective than nasal sprays, and should be offered to adults with at least moderate symptoms such as breathing disruption, suggests a UK trial published by The BMJ today.

18 Oct 2023

Deep learning algorithm identifies antimalarial drug as promising treatment for osteoporosis

Artificial intelligence has exploded in popularity and is being harnessed by some scientists to predict which molecules could treat illnesses, or to quickly screen existing medicines for new applications.

18 Oct 2023

Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.

17 Oct 2023

Strengthening the immune system to fight cytomegalovirus on its own

Some viruses can be dormant throughout a person's life and cause no harm but become dangerous when the immune system is weakened.

17 Oct 2023

Fluorescence lifetime imaging shows promise for improved tumor detection

Removing a patient's tumor while sparing healthy tissue requires exquisite precision, but often surgeons must rely on their eyes and hands to determine where to cut.

16 Oct 2023

Survey highlights gaps in the UK public's awareness of childhood cancer signs and symptoms

There are significant gaps in the UK public's awareness of the tell-tale signs and symptoms of cancer in children and teens, with just a third of adults expressing confidence in being able to recognize them, find the results of a nationally representative survey published online in the journal Archives of Disease in Childhood.

16 Oct 2023

How does nutrition influence osteoarthritis prevention and management?

The influence of nutrition on osteoarthritis (OA).

16 Oct 2023

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

The study explores the efficacy of variant-adapted COVID-19 booster vaccines, particularly against new strains like Omicron. It raises questions about the need for annual updates and the best technologies for long-term, durable immunity.

15 Oct 2023

Rare ‘flesh-eating’ bacterium spreads North as oceans warm

Debbie King barely gave it a second thought when she scraped her right shin climbing onto her friend's pontoon for a day of boating in the Gulf of Mexico on Aug. 13.

13 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Study highlights ways to identify children at high risk of type 2 diabetes and prevention strategies

A new Journal of the Endocrine Society study highlights how to identify children at high risk of developing type 2 diabetes and strategies for prevention, such as anti-obesity or anti-diabetes medication and lifestyle changes.

12 Oct 2023

Is there an association between vitamin D deficiency and sepsis mortality?

The impact of deficient serum vitamin D levels on sepsis prognosis.

12 Oct 2023

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation.

11 Oct 2023

Is a vegan diet a healthy choice for kids?

In a comprehensive review published in Critical Reviews in Food Science and Nutrition, scientists analyzed the health implications of vegan diets in children and adolescents. The study reveals both benefits and concerns, highlighting lower cholesterol levels but potential nutritional deficiencies that might affect bone health.

10 Oct 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Delaying ACL surgery in children linked to higher risk of new knee injuries

A Johns Hopkins Children's Center study of medical records concludes that delaying surgical treatment of the anterior cruciate ligament, or ACL, in some children is associated with a higher risk of new tears in the meniscus and cartilage after the initial injury to the ligament, which helps join the thigh bone to the shin bone.

10 Oct 2023

Yale researchers uncover key role of protein CXCR4 in pregnancy

Immune cells play a key role during pregnancy, adjusting immune system response in a way that enables the fetus to develop while also protecting the parent and fetus from outside assaults like viruses.

10 Oct 2023

New AI tool could aid in the diagnosis of enigmatic rare diseases

An innovative AI-based tool leverages varied symptom descriptions, along with evidence from the scientific literature and genomic datasets, to pinpoint disease-associated gene variants.

10 Oct 2023

Bone News and Research

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Turning brain immune cells into neurons restores brain function after stroke-like injury in mice

Surgery to straighten a crooked septum more effective than nasal sprays, trial suggests

Deep learning algorithm identifies antimalarial drug as promising treatment for osteoporosis

Lung chip model offers new insights into how radiation damages the lungs

Strengthening the immune system to fight cytomegalovirus on its own

Fluorescence lifetime imaging shows promise for improved tumor detection

Survey highlights gaps in the UK public's awareness of childhood cancer signs and symptoms

How does nutrition influence osteoarthritis prevention and management?

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

Rare ‘flesh-eating’ bacterium spreads North as oceans warm

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

Study highlights ways to identify children at high risk of type 2 diabetes and prevention strategies

Is there an association between vitamin D deficiency and sepsis mortality?

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Is a vegan diet a healthy choice for kids?

DNA aptamers: A versatile tool for regenerative medicine and beyond

Delaying ACL surgery in children linked to higher risk of new knee injuries

Yale researchers uncover key role of protein CXCR4 in pregnancy

New AI tool could aid in the diagnosis of enigmatic rare diseases

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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