Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Head and neck cancer survivors more likely to commit suicide

Despite improved survival rates among cancer patients, the risk of death by suicide remains high, especially among those treated for head and neck cancers.

25 Oct 2018

Combination therapy enhances wound healing

By incorporating a gene-suppressing drug into an over-the-counter gel, researchers at Albert Einstein College of Medicine and their colleagues cut healing time by half and significantly improved healing outcomes compared to control treatments.

25 Oct 2018

Alcohol changes the molecular basis of memory formation

A new study has shown how alcohol consumption fuels addiction by hijacking a conserved memory pathway in the brain and changing memory formation.

25 Oct 2018

Researchers find improvement in liver transplant survival rate among older recipients

An increasing number of older adults are diagnosed with end-stage liver disease. End-stage liver disease is a life-threatening condition in which the liver stops working normally.

23 Oct 2018

Map of human liver cells reveals molecular make-up of individual cells

A map of the cells in the human liver has been created by University Health Network Transplant Program and University of Toronto researchers, revealing for the first time differences between individual cells at the molecular level which can have a profound impact on their behaviour in tissue, tumours and disease.

From 10x Genomics, Inc. 23 Oct 2018

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

With a pair of RO1 grants from the National Institutes of Health, pain researcher Daniela Salvemini, Ph.D., will embark on two new research projects, studying chemotherapy-induced cognitive impairment, or "chemo brain," symptoms and unwanted side effects of opioids.

23 Oct 2018

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

UT Southwestern biochemist Dr. Zhijian "James" Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body's immune defense against infections and cancers.

19 Oct 2018

Study reports increased risk of death in children with inflammatory bowel disease

Children who develop inflammatory bowel disease (ulcerative colitis or Crohn's disease) have an increased risk of death, both in childhood and later in life, a study from Karolinska Institutet in Sweden published in the journal Gastroenterology reports.

19 Oct 2018

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

With an estimated twenty-thousand protein-coding genes in the human genome, pinpointing a specific gene or pathway responsible for a particular disease can be like finding a needle in the proverbial haystack.

17 Oct 2018

One-time universal screening recommended to tackle increase in hepatitis C

Physicians are encountering a growing number of younger patients who are testing positive for hepatitis C virus fueled largely by the opioid crisis impacting communities around the country.

17 Oct 2018

Study highlights need for increased support for alcohol-related liver disease patients

Two in three ALD patients admitted to an intensive care unit (ICU) survived for less than a year afterwards, the study shows.

15 Oct 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Low levels of cellular copper may make fat cells fatter

In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.

11 Oct 2018

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

Carnegie's Department of Embryology scientist Steven Farber and team have been awarded a 5-year $3.3-million NIH grant to identify novel pharmaceuticals for combatting a host of diseases associated with altered levels of lipoproteins like LDL ("bad cholesterol").

11 Oct 2018

King's College researchers awarded £2.3 million for new trial to treat liver disease

Dr Mark McPhail from the Department of Inflammation Biology, School of Immunology & Microbial Sciences and Dr Vishal Patel from the Institute of Liver Studies at King's College Hospital have been awarded £2.3 million by the National Institute of Health Research Health Technology Assessment to lead a new UK wide multi-centre trial to treat liver disease.

9 Oct 2018

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Researchers have successfully used prenatal gene editing (CRISPR-Cas9) to prevent a fatal metabolic disorder in an animal model.

8 Oct 2018

Study shows possibility of using PET imaging to manage chronic liver diseases

While liver biopsies are powerful and reliable, they are also invasive, painful, limited and subject to complications. These effects may soon be a thing of the past for some patients thanks to new research showing PET imaging with the 18F-FAC radiotracer can be used as a non-invasive substitute. The study is featured in the October issue of The Journal of Nuclear Medicine.

5 Oct 2018

Wits doctors transplant liver from HIV positive mother to her child with end-stage liver disease

This was the ethical dilemma faced by doctors at Wits Donald Gordon Medical Centre to save a child's life.

4 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

Study examines link between alcohol consumption and death risk in patients with NAFLD

Non-Alcoholic Fatty Liver Disease, which is not caused by significant alcohol consumption, has become the most common liver disease in the United States and comprises more than two thirds of patients with chronic liver disease.

3 Oct 2018

Liver Disease News and Research

Further Reading

Head and neck cancer survivors more likely to commit suicide

Combination therapy enhances wound healing

Alcohol changes the molecular basis of memory formation

Researchers find improvement in liver transplant survival rate among older recipients

Map of human liver cells reveals molecular make-up of individual cells

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

Study reports increased risk of death in children with inflammatory bowel disease

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

One-time universal screening recommended to tackle increase in hepatitis C

Study highlights need for increased support for alcohol-related liver disease patients

Metabolome tests could be new way to measure obesity and health

Low levels of cellular copper may make fat cells fatter

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

King's College researchers awarded £2.3 million for new trial to treat liver disease

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Study shows possibility of using PET imaging to manage chronic liver diseases

Wits doctors transplant liver from HIV positive mother to her child with end-stage liver disease

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Study examines link between alcohol consumption and death risk in patients with NAFLD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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