Neurodegenerative Diseases News and Research

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Researchers use AI methods to 'redefine' Alzheimer's disease

As the search for successful Alzheimer's disease drugs remains elusive, experts believe that identifying biomarkers -- early biological signs of the disease -- could be key to solving the treatment conundrum.

14 Oct 2020

Enzyme SSH1 impairs the disposal of damaged tau and neurotoxic mitochondria

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

12 Oct 2020

Neurobiologists decode central mechanism of degenerative processes in brains of mouse models

Heidelberg neurobiologists decode central mechanism of degenerative processes in the brains of mouse models and develop new principle for therapeutic agents

9 Oct 2020

New computer program detects neurodegeneration biomarkers through magnetic resonance imaging

Magnetic resonance imaging is the most sensitive and reliable technique for diagnosing and monitoring neurodegenerative diseases.

8 Oct 2020

NTHU research could have significant impact on the treatment of dementia

One of the causes of neurodegenerative diseases such as Parkinson's and Alzheimer's is the calcification of the basal nucleus of the brain, which blocks the membrane protein channels on the surface of brain cells, preventing the transmission of signal molecules and nutrients to the cells.

8 Oct 2020

Research team discovers a new key player in long-term memory

A McGill-led multi-institutional research team has discovered that during memory consolidation, there are at least two distinct processes taking place in two different brain networks - the excitatory and inhibitory networks.

7 Oct 2020

Why do we need sleep?

In this interview, Dr. Gina Poe speaks to News-Medical about why we sleep, and the importance of REM sleep for brain development.

7 Oct 2020

NIH awards $3.8 million to predict dementia in patients with Parkinson's disease

The National Institute of Neurological Disorders and Stroke at the National Institutes of Health has awarded a grant expected to total $3.8 million to Virendra Mishra, Ph.D., associate staff at Cleveland Clinic Lou Ruvo Center for Brain Health, to identify biomarkers - or disease indicators - to predict dementia in patients with Parkinson's disease.

6 Oct 2020

Study shows how amino acids are transported across liposome and cell membranes

The transport of amino acids and other molecules across the cell's membrane plays a crucial role in the metabolism of cells and, therefore, in human health.

6 Oct 2020

New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies.

1 Oct 2020

First pathoconnectome shows how eye disease alters retinal circuitry

Scientists from the John A. Moran Eye Center at the University of Utah have achieved another first in the field of connectomics, which studies the synaptic connections between neurons.

30 Sep 2020

New study links 160 genes to brain shrinkage

A new study implicates 160 genes in brain shrinkage seen on MRIs of 45,000 healthy adults. The shrinkage is in the cortex, the dimply outer layer of the brain that gives rise to thinking, awareness and action, and largely consists of gray matter.

25 Sep 2020

NIH awards $1.9 million STTR grant to fast track new class of non-opioid pain relievers

The National Institute of Neurological Disorders and Stroke of the National Institutes of Health (NIH) has awarded a $1.9 million Fast-Track Small Business Technology Transfer grant to South Rampart Pharma.

25 Sep 2020

Study highlights the importance of healthy placental development in pregnancy

The first stages of placental development take place days before the embryo starts to form in human pregnancies. The finding highlights the importance of healthy placental development in pregnancy, and could lead to future improvements in fertility treatments such as IVF, and a better understanding of placental-related diseases in pregnancy.

25 Sep 2020

Berlin researchers are pursuing the development of passive vaccination

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development of a passive vaccination.

25 Sep 2020

Dextran sulphate-induced tau assemblies cause tau propagation in non-transgenic mice

Accumulation of assembled tau protein in the central nervous system is characteristic of Alzheimer's disease and several other neurodegenerative diseases, called tauopathies.

23 Sep 2020

Chaperone-mediated autophagy could be a new therapeutic target for spinocerebellar ataxia

A research team from Kumamoto University, Japan has developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated autophagy (CMA) in cerebellar neurons.

23 Sep 2020

Neurodegenerative Diseases News and Research

Researchers use AI methods to 'redefine' Alzheimer's disease

Enzyme SSH1 impairs the disposal of damaged tau and neurotoxic mitochondria

Neurobiologists decode central mechanism of degenerative processes in brains of mouse models

New computer program detects neurodegeneration biomarkers through magnetic resonance imaging

NTHU research could have significant impact on the treatment of dementia

Research team discovers a new key player in long-term memory

Why do we need sleep?

NIH awards $3.8 million to predict dementia in patients with Parkinson's disease

Study shows how amino acids are transported across liposome and cell membranes

New, rare genetic form of dementia discovered

First pathoconnectome shows how eye disease alters retinal circuitry

New study links 160 genes to brain shrinkage

NIH awards $1.9 million STTR grant to fast track new class of non-opioid pain relievers

Study highlights the importance of healthy placental development in pregnancy

Berlin researchers are pursuing the development of passive vaccination

Dextran sulphate-induced tau assemblies cause tau propagation in non-transgenic mice

Chaperone-mediated autophagy could be a new therapeutic target for spinocerebellar ataxia

ALS and FTLD result from reduced transportation of messenger RNA

Innovative approach for identifying new molecules to help track progression of Parkinson's

Biomarker for earlier diagnosis of neurodegenerative diseases detected in the eye

eBook: Using iPSCs models for human disease research and drug discovery eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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