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Study sheds light on the deadly venom of Mojave rattlesnakes

The Mojave rattlesnake, living in the deserts of the southwestern United States and central Mexico, is characterized by its lethal venom that can either shut down your body or tenderize your insides. Clemson University researchers say which one depends on where you're located.

16 Jan 2019

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications.

11 Jan 2019

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

In nature, certain molecules with the same chemical composition, can exist in two different shapes that are mirrors images of each other, much like our hands.

11 Jan 2019

Neuropeptide Y may hold key to exacerbating severe influenza

Severe influenza virus infection is characterized by a strong inflammatory response and profuse viral replication in lungs. These viruses, such as the notorious avian flu, have a high rate of death and to date there are no effective treatments.

10 Jan 2019

High-performing MS device reaches new level in characterizing protein impurities

In response to current regulatory guidance a Mass Spectrometry-based Host Cell Protein detection approach with faster, more accurate and wider-ranging detection is essential.

10 Jan 2019

Aptamer Group and AstraZeneca to develop new drug delivery vehicles

Aptamer Group today announced it has signed an agreement with AstraZeneca to explore the potential of using aptamer technology to target the kidney.

From AstraZeneca 10 Jan 2019

Expedeon signs license agreement for use of Lightning-Link technology

Expedeon AG, today announced it has signed a supply and license agreement with Cell Guidance Systems for use of Expedeon’s proprietary Lightning-Link Rapid Biotin..

9 Jan 2019

Biomarkers identified that could predict the risk of stroke

Researchers have successfully developed two biomarkers that could help predict the risk of a heart condition and stroke.

7 Jan 2019

Newly discovered biomarkers can help identify heart condition in patients who have three 'clinical risks'

Researchers at the University of Birmingham have found two biomarkers that could be used to identify a heart condition known as atrial fibrillation in patients who have three 'clinical risks'.

7 Jan 2019

Common food additive could cause celiac disease, review says

Research suggests that celiac disease could be caused by a bacterial enzyme used to manufacture sausages, cheese, bread and other processed foods.

7 Jan 2019

New medications provide better treatment for alcohol use disorders, chronic pain, mood disorders

Helping people with addictions has become a research passion for Purdue University's Richard van Rijn, who is leading a team to make drug discoveries to support millions around the world dealing with alcohol use disorders, chronic pain and mood disorders.

3 Jan 2019

Nature-based antibiotic molecules for treatment of infections

New developments in antimicrobial peptides (AMPs) with antibiofilm properties are rapidly materializing.

2 Jan 2019

Peptide isolated from spirulina extract may counteract arterial hypertension

Spirulina is more and more celebrated as a "superfood" because of its possible beneficial properties, albeit its mechanism of action is still subjected to investigation. With the scientific name of Arthrospira platensis, spirulina is a cyanobacterium, a bacterium capable of photosynthesis. Sometimes classified as a "blue algae", it was supposedly used as a food by the Aztecs.

31 Dec 2018

Study uncovers how skin ages, loses fat and immunity

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving the skin a plump, youthful look and producing a peptide that plays a critical role in fighting infections.

27 Dec 2018

The role of galanin-like peptide in regulating feeding behavior and energy metabolism

Galanin-like peptide is a short peptide made up of 60 amino acid residues. This sequence is homologous across several species. The hypothalamic arcuate nucleus is the place where GALP is produced. GALP has diverse physiological effects such as the regulation of feeding, energy metabolism, and reproductive behavior.

25 Dec 2018

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Lysosomes are filled with more than 50 different hydrolytic enzymes, which are capable of digesting most cellular components.

23 Dec 2018

Researchers discover new changes occurring in the brain in early Alzheimer's disease

Researchers at the University of Eastern Finland have discovered new changes occurring in the human brain in the early stages of Alzheimer's disease.

21 Dec 2018

GW researchers receive NIH funding to study causes of high risk of heart disease in HIV patients

Atherosclerosis and cardiovascular disease are major complications of HIV infection and cannot currently be treated by antiretroviral treatments.

21 Dec 2018

Researchers synthesize new compound that inhibits replication of hepatitis C virus

A new compound that inhibits the replication of hepatitis C virus in several stages of its lifecycle - and is also capable of acting on bacteria, fungi and cancer cells - has been synthesized by researchers at São Paulo State University in Brazil.

19 Dec 2018

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

An international team coordinated by the Interdisciplinary Research Structure in Biotechnology and Biomedicine of the University of Valencia has proved how the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to the biochemical research for decades.

19 Dec 2018

Peptides News and Research

Study sheds light on the deadly venom of Mojave rattlesnakes

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

Neuropeptide Y may hold key to exacerbating severe influenza

High-performing MS device reaches new level in characterizing protein impurities

Aptamer Group and AstraZeneca to develop new drug delivery vehicles

Expedeon signs license agreement for use of Lightning-Link technology

Biomarkers identified that could predict the risk of stroke

Newly discovered biomarkers can help identify heart condition in patients who have three 'clinical risks'

Common food additive could cause celiac disease, review says

New medications provide better treatment for alcohol use disorders, chronic pain, mood disorders

Nature-based antibiotic molecules for treatment of infections

Peptide isolated from spirulina extract may counteract arterial hypertension

Study uncovers how skin ages, loses fat and immunity

The role of galanin-like peptide in regulating feeding behavior and energy metabolism

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Researchers discover new changes occurring in the brain in early Alzheimer's disease

GW researchers receive NIH funding to study causes of high risk of heart disease in HIV patients

Researchers synthesize new compound that inhibits replication of hepatitis C virus

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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