Immune System News and Research

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CD137 T cell activation molecule can help identify rare antitumor T cells in human cancers

Patients with tumors that contain increased numbers of T lymphocytes generally survive longer than those with tumors without T-cell involvement, suggesting that T cells with potent antitumor function naturally exist in cancer and control tumor progression. With the exception of melanoma, it has been difficult to identify and isolate the tumor-reactive T cells from common cancers, however, the ability to do so could be used to fight a patient's own cancer.

14 Nov 2013

Severe sepsis mortality rates decrease over the past 20 years

A recent study from Boston University School of Medicine and Boston Medical Center shows a significant decrease in severe sepsis mortality rates over the past 20 years. Looking at data from patients with severe sepsis enrolled in clinical trials, researchers found that in-hospital mortality rates decreased from 47 percent between 1991 and 1995 to 29 percent between 2006 and 2009, a time period when no new pharmacological treatments were developed for severe sepsis.

14 Nov 2013

Stem cells from Wolfram syndrome patients used to elucidate beta-cell failure pathway in diabetes

Scientists from the New York Stem Cell Foundation Research Institute and Columbia University Medical Center have used stem cells created from the skin of patients with a rare form of diabetes—Wolfram syndrome—to elucidate an important biochemical pathway for beta-cell failure in diabetes. The findings by Linshan Shang and colleagues were published today in Diabetes.

13 Nov 2013

Sunscreen application and skin cancer: an interview with Dr Michelle Hunt, Inner Sydney Dermatology

Unfortunately the incidence of skin cancer has risen in Australia over the past decades. From 1982 to 2007, melanoma diagnosis increased by around 50%, and in 2011, 1544 people died due to melanoma.

13 Nov 2013

immatics, Roche enter into cancer vaccine and immunotherapy deal

immatics biotechnologies GmbH and Roche today announced a strategic research and development collaboration covering multiple cancer vaccines and immunotherapeutics.

13 Nov 2013

Researchers discover powerful mechanism that keeps white blood cells from going rogue

The immune system is a double-edged sword. While its primary role is to fight infections, it can also become overactive, leading to problems like allergies and autoimmune diseases.

13 Nov 2013

National Inventors Hall of Fame picks winners at 2013 Collegiate Inventors Competition

An invention that strips cancer tumors' ability to hide from the body's immune system, and a better way to shock hearts back into their normal rhythm took top honors today at America's most prestigious collegiate inventing competition.

13 Nov 2013

Tailored doses of pre-transplant drug therapy in Glaucomatous patients boosts survival rates to over 90%

Chronic Granulomatous Disease is a rare immune deficiency that seriously compromises organ function and is life-threatening, with 20-30 per cent of patients dying within the first two decades of life.

13 Nov 2013

Researchers shed light on how and when immune system forms

Researchers at Lund University have shed light on how and when the immune system is formed, raising hope of better understanding various diseases in children, such as leukaemia.

13 Nov 2013

Researchers receive $7.5 million NIH grant to develop novel therapies for Alzheimer's disease

Researchers at Mayo Clinic in Florida, the University of Florida in Gainesville, and the Institute for Systems Biology in Seattle have received a $7.5 million grant from the National Institutes of Health to take a new and more expanded approach to identifying drug targets to treat and possibly prevent Alzheimer's disease.

12 Nov 2013

Furamidine drug may also be useful in treating cancers, immune-related diseases

A class of drugs used to treat parasitic infections such as malaria may also be useful in treating cancers and immune-related diseases, a new WSU-led study has found.

12 Nov 2013

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Northwestern Medicine- scientists have successfully tested a nontoxic therapy that suppresses Lupus in blood samples of people with the autoimmune disease.

12 Nov 2013

Study provides new evidence underlining the significance of bitter taste perception

It's no coincidence that the expression "to leave a bitter taste in one's mouth" has a double meaning; people often have strong negative reactions to bitter substances, which, though found in healthful foods like vegetables, can also signify toxicity. For this reason, the ability to sense bitterness likely played an important role in human evolution.

12 Nov 2013

Australian scientists unravel mystery behind immune system memory

While the principle of immune memory has been known for decades, the exact molecular mechanisms underpinning it have remained a mystery. Australian scientists have now unraveled part of that mystery, identifying the role of a gene called STAT3, which acts as a kind of roundabout, directing chemical messenger molecules to various destinations.

12 Nov 2013

Research: New mechanisms and areas of brain linked with anxiety and depression

Research released today reveals new mechanisms and areas of the brain associated with anxiety and depression, presenting possible targets to understand and treat these debilitating mental illnesses.

12 Nov 2013

Gene mutations responsible for persistent AD in African American children

Two specific genetic variations in people of African descent are responsible for persistent atopic dermatitis (AD), an itchy, inflammatory form of the skin disorder eczema. A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss-of-function mutations to Filaggrin-2 (FLG2), a gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.

12 Nov 2013

Study: Hospitals vary in management of children with traumatic brain injury

Hospitals vary in management of children with traumatic brain injury—particularly in monitoring and preventing the harmful effects of increased intracranial pressure (ICP), according to a study in the November issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

12 Nov 2013

Researchers discovers key genetic culprit responsible for growth, metastasis of colon cancer

Chronic inflammation has long been known as a key risk factor for cancer---particularly colon cancer---but the exact mechanisms of how inflammation heightens the immune response, and ultimately influences the initiation and progression of cancer have remained elusive.

12 Nov 2013

Georgia University scientists identify cause of muscle weakness disease myasthenia gravis

An antibody to a protein critical to enabling the brain to talk to muscles has been identified as a cause of myasthenia gravis, researchers report.

12 Nov 2013

Researchers find zinc starves bacteria by preventing its uptake of essential metal

Australian researchers have found that zinc can 'starve' one of the world's most deadly bacteria by preventing its uptake of an essential metal.

11 Nov 2013

Immune System News and Research

CD137 T cell activation molecule can help identify rare antitumor T cells in human cancers

Severe sepsis mortality rates decrease over the past 20 years

Stem cells from Wolfram syndrome patients used to elucidate beta-cell failure pathway in diabetes

Sunscreen application and skin cancer: an interview with Dr Michelle Hunt, Inner Sydney Dermatology

immatics, Roche enter into cancer vaccine and immunotherapy deal

Researchers discover powerful mechanism that keeps white blood cells from going rogue

National Inventors Hall of Fame picks winners at 2013 Collegiate Inventors Competition

Tailored doses of pre-transplant drug therapy in Glaucomatous patients boosts survival rates to over 90%

Researchers shed light on how and when immune system forms

Researchers receive $7.5 million NIH grant to develop novel therapies for Alzheimer's disease

Furamidine drug may also be useful in treating cancers, immune-related diseases

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Study provides new evidence underlining the significance of bitter taste perception

Australian scientists unravel mystery behind immune system memory

Research: New mechanisms and areas of brain linked with anxiety and depression

Gene mutations responsible for persistent AD in African American children

Study: Hospitals vary in management of children with traumatic brain injury

Researchers discovers key genetic culprit responsible for growth, metastasis of colon cancer

Georgia University scientists identify cause of muscle weakness disease myasthenia gravis

Researchers find zinc starves bacteria by preventing its uptake of essential metal

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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