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Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Two clinical trials led by Johns Hopkins Kimmel Cancer Center researchers in collaboration with other medical centers, testing experimental drugs aimed at restoring the immune system's ability to spot and attack cancer, have shown promising early results in patients with advanced non-small cell lung cancer, melanoma, and kidney cancer.

2 Jun 2012

Lapatinib-pazopanib combination therapy not beneficial for patients with inflammatory breast cancer

Inflammatory breast cancer is a very aggressive type of cancer associated with early metastasis and poor survival rates, and the prognosis is even worse for patients with tumors expressing the ErbB2 receptor. The ErbB2-inhibiting drug lapatinib can slow the spread of cancer cells in individuals with advanced breast cancer who have already tried other chemotherapy medications.

2 Jun 2012

Two tumor suppressor genes function to disrupt overactive EGFR signaling

Overactive epidermal growth factor receptor (EGFR) signaling has been linked to the development of cancer. Several drug therapies have been developed to treat these EGFR-associated cancers; however, many patients have developed resistance to these drugs and are therefore no longer responsive to drug treatment.

2 Jun 2012

PMTCT of HIV 'critical, effective' to making progress in child survival

In this post in the Management Sciences for Health's (MSH) "Global Health Impact" blog, Scott Kellerman, global technical lead for HIV/AIDS at MSH, discusses USAID's "Every Child Deserves a 5th Birthday" campaign and recent attention to the prevention of mother-to-child transmission (PMTCT) of HIV.

2 Jun 2012

Walnuts make a nutritious snack

Ninety percent of American adults snack daily and could be gaining valuable nutrition. A paper published in the British Journal of Nutrition found that smaller nutritious meals eaten throughout the day contribute significantly to the nutrient quality of the diet. The key is making snacking choices that are not "empty calories" but healthful options, providing important vitamins and minerals.

2 Jun 2012

Chagas disease could pose threat similar to other global pandemics, experts warn

"Researchers are warning that the little-known Chagas disease could pose a threat similar to other global pandemics," Fox News reports, noting Chagas disease "is a parasitic illness that is most commonly transmitted by the so-called 'kissing bugs,' a subfamily of blood-sucking insects, through the parasite called Trypanosoma cruzi" (5/31).

2 Jun 2012

Research roundup: Changing unhealthy diets with mobile tech; ACOs for Medicaid

Multiple Behavior Changes In Diet And Activity -- Mobile technologies have been touted for their potential benefits to health and wellness. Researchers in this study gave 204 individuals a dieting and exercise regimen. They also gave each person a handheld device to record adherence and receive remote coaching.

2 Jun 2012

New assay to test for newborn exposure to designer stimulants

United States Drug Testing Laboratories, Inc, a reference laboratory specializing in alcohol and substances of abuse testing, released a new assay testing umbilical cord for newborn exposure in utero to Designer Stimulants/ Bath Salts on Friday, June 1, 2012. The CordStat® assay screens for the most common of designer stimulants known as "Bath Salts."

2 Jun 2012

Global generic pharmaceuticals market to reach $231.00 billion in 2017 at 9.29% CAGR

The global generic pharmaceuticals market is likely to witness strong growth in the next few years owing to the patent expiration of key blockbuster drugs and the judicious cost containment efforts of governments and healthcare service providers worldwide.

2 Jun 2012

Local anesthetic mixed with magnetized 'ferrofluids' may prevent rare complication of spinal anesthesia

An simple technique using local anesthetic mixed with magnetized "ferrofluids" may provide a new approach to preventing a rare but serious complication of spinal anesthesia, reports the June issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

2 Jun 2012

Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer

Investigators at The Cancer Institute of New Jersey (CINJ) have partnered with the National Cancer Institute (NCI) and launched a clinical trial examining the effectiveness of a combined vaccine and hormone treatment for prostate cancer that is resistant to hormone therapy and not visible on imaging tests such as a CT scan and a bone scan.

2 Jun 2012

New web-based cessation program takes smokers from preparation to quit date

StopAdvisor is a new web-based smoking cessation program, which takes smokers from preparation for the target quit date to the quit date itself. It achieves this by offering expert advice through a combination of interactive menus and personalised sessions.

2 Jun 2012

Electronic nose and optoacoustics improve diagnosis of prostate cancer

Chances of survival of prostate cancer depend strongly on the stage at which the disease is diagnosed. Now scientists have developed new methods relying on an electronic nose and optoacoustics to improve the diagnosis techniques and avoid fatal treatment delays

2 Jun 2012

N.Y. Catholics split on bishops' lawsuit over contraception rule

In political developments, a new poll shows a significant divide among Catholics but little support among general voters for the church's complaints about the Obama administration rule. Also, in Minnesota, a new candidate opens his campaign for Congress and criticizes the state's handling of Medicaid funds.

2 Jun 2012

Beneficial design element in sunitinib phase III clinical trial for gastrointestinal stromal tumors

Patients benefitted from an important design element in the pivotal phase III clinical trial that led to Food and Drug Administration and worldwide regulatory approval of sunitinib for the treatment of gastrointestinal stromal tumors resistant to the only other available therapy, according to a study in Clinical Cancer Research, a journal of the American Association for Cancer Research.

2 Jun 2012

UH CNRCS students achieve significant milestones in cancer therapy research

Four University of Houston (UH) students are well on their way to emerging cancer research careers upon achieving significant milestones this spring in their work toward new therapies for prostate and breast cancer.

2 Jun 2012

Expanding role of modeling and simulation across drug development lifecycle

Quintiles today issued the first of three white papers on the expanding role of modeling and simulation across the drug development lifecycle. "Lifecycle Modeling and Simulation: Current Practice and Future Impact on Healthcare Innovation and Delivery" discusses the potential of modeling and simulation to advance healthcare delivery through applications in drug development.

2 Jun 2012

Two pharma companies plan international trials into targeted cancer treatments in the UK

A Cancer Research UK initiative to improve cancer gene testing has prompted two pharmaceutical companies to plan pioneering international trials into targeted cancer treatments in the UK.

2 Jun 2012

'Atzelberg Circle' researchers meet to advance hyperthermia as standard combination cancer therapy

BSD Medical Corporation, a developer and manufacturer of advanced medical systems that utilize heat therapy to treat cancer, announced today that a distinguished, international team of leading oncologists met in council while attending the May 2012 conference of the European Society for Radiotherapy and Oncology (ESTRO) in Barcelona, Spain.

2 Jun 2012

Exercise reduces expression of cytokines and alleviates neuropathic pain

Exercise helps to alleviate pain related to nerve damage (neuropathic pain) by reducing levels of certain inflammation-promoting factors, suggests an experimental study in the June issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

2 Jun 2012

Research News and Research

Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Lapatinib-pazopanib combination therapy not beneficial for patients with inflammatory breast cancer

Two tumor suppressor genes function to disrupt overactive EGFR signaling

PMTCT of HIV 'critical, effective' to making progress in child survival

Walnuts make a nutritious snack

Chagas disease could pose threat similar to other global pandemics, experts warn

Research roundup: Changing unhealthy diets with mobile tech; ACOs for Medicaid

New assay to test for newborn exposure to designer stimulants

Global generic pharmaceuticals market to reach $231.00 billion in 2017 at 9.29% CAGR

Local anesthetic mixed with magnetized 'ferrofluids' may prevent rare complication of spinal anesthesia

Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer

New web-based cessation program takes smokers from preparation to quit date

Electronic nose and optoacoustics improve diagnosis of prostate cancer

N.Y. Catholics split on bishops' lawsuit over contraception rule

Beneficial design element in sunitinib phase III clinical trial for gastrointestinal stromal tumors

UH CNRCS students achieve significant milestones in cancer therapy research

Expanding role of modeling and simulation across drug development lifecycle

Two pharma companies plan international trials into targeted cancer treatments in the UK

'Atzelberg Circle' researchers meet to advance hyperthermia as standard combination cancer therapy

Exercise reduces expression of cytokines and alleviates neuropathic pain

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