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Combination therapies can shrink lung tumors in mice and human cancer cells

Combining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells, finds a new study led by the Francis Crick Institute and The Institute of Cancer Research, London.

17 Sep 2019

World Alzheimer’s Day 2019: A timely reminder of urgent need for new drugs to tackle disease

As World Alzheimer’s Day 2019 approaches (21 September), with the aim this year of raising global awareness and understanding of the stigma, stereotypes and myths that surround a dementia diagnosis;

17 Sep 2019

Attana invited to showcase latest applications at National University of Singapore's Life Sciences day

Attana is invited to present at the National University of Singapore's Life Sciences Institute Core Facilities Day - NUS Medical Sciences Cluster on Thursday September 20th. In particular, Attana is invited to show Attana's leading applications for interaction characterization of CAR-T cells and tumor tissues.

17 Sep 2019

Drug-sparing HIV regimens have become new standards of care, says GlobalData

Reductions in pill burden and dosing, improvements in safety and tolerability, and increased barriers to resistance have changed HIV management.

17 Sep 2019

Researchers study typhoid genomes of travelers from different parts of the world

Salmonella enterica serovar Typhi causes more than 20 million cases of typhoid fever each year, and disproportionately infects children in low and middle income countries.

From PLOS ONE 17 Sep 2019

Mutated ciliary genes tied to heart valve birth defect

The heart pumps blood throughout the body to provide the needed oxygen and nutrients. In the heart, blood flows to get oxygen from the lungs to deliver to the cells. Some of the most important structures in the heart are the valves, because they prevent the backflow of blood, avoiding the mixture of oxygenated blood with the ones that still need to be oxygenated.

17 Sep 2019

New method developed to address failures in promising anti-cancer drug

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve the efficacy, accuracy and longevity of certain cancer therapies.

17 Sep 2019

Study sheds light on the metabolism of Leishmania parasite

University of York scientists are part of an international team which has discovered how a parasite responsible for spreading a serious tropical disease protects itself from starvation once inside its human host.

17 Sep 2019

New therapeutic target for rheumatoid arthritis and type 2 diabetes

There is a growing body of knowledge that points that type 2 diabetes, a chronic disease where the blood sugar increases, is an inflammatory disease. The levels of certain inflammatory chemicals, dubbed as cytokines, are often higher in people with type 2 diabetes, than healthy people.

16 Sep 2019

Brain activity intensity appears to increase our need for sleep

The intensity of brain activity during the day, notwithstanding how long we've been awake, appears to increase our need for sleep, according to a new UCL study in zebrafish.

16 Sep 2019

Women killed by their partner constitute a major proportion of homicide statistics in Denmark

Out of the 536 women who were killed between 1992-2016 in Denmark, 300 were killed by their partner. This figure corresponds to 57 per cent of all homicides with female victims.

16 Sep 2019

New platform uses nanoparticles to deliver anti-cancer agent to cells

Scientists from the University of Cambridge have developed a platform that uses nanoparticles known as metal-organic frameworks to deliver a promising anti-cancer agent to cells.

16 Sep 2019

What you eat may change the way that antibiotics affect your gut

Scientists have examined how antibiotics change the gut bacteria in mice and looked at how diet may exacerbate or mitigate these changes.

16 Sep 2019

Researchers eliminate need for anti-rejection drugs in mice with transplanted glial cells

In experiments in mice, Johns Hopkins Medicine researchers say they have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs.

16 Sep 2019

Purveyors of black-market pharmaceuticals target immigrants

The bootleg medications were smuggled across the border and sold to mostly Latino immigrants in public spaces throughout Los Angeles — at swap meets, parks, beauty salons and makeshift stands outside mom-and-pop grocery stores.

16 Sep 2019

Study finds rise in off-label medication orders for children

U.S. physicians are increasingly ordering medications for children for conditions that are not approved by the Food and Drug Administration, according to a Rutgers study.

16 Sep 2019

Men and women with diabetes or prediabetes experience different comorbidities, study shows

A new study presented at this year's Annual Meeting of the European Association for the Study of Diabetes in Barcelona, Spain (16-20 Sept) shows that men and women experience different comorbidities (other diseases at the same time) as having diabetes or prediabetes, as well as an unexpectedly high rate of prediabetes among children aged 6-10 years.

16 Sep 2019