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Researchers discover potential of antihistamines that cause death of leukemic stem cells

Ruth M. Risueño leads the Leukaemic Stem Cell group of the Josep Carreras Leukaemia Research Institute. This group investigates Acute Myeloid Leukemia and the cell population responsible for the disease spreading, persisting, and if it has been treated and overcome, reappear.

6 Sep 2019

Vast majority of footballers in the Spanish League unaware of banned substances

The vast majority (97.4%) of players with the Spanish League are unfamiliar with the list of substances banned by the World Anti-Doping Agency (WADA). Furthermore, 95% do not even know what this agency is for.

6 Sep 2019

Serotonin and anti-depressants can have a major effect on the gut's microbiota

A new study in mice led by UCLA biologists strongly suggests that serotonin and drugs that target serotonin, such as anti-depressants, can have a major effect on the gut's microbiota -- the 100 trillion or so bacteria and other microbes that live in the human body's intestines.

6 Sep 2019

New gold-based molecules more effective at killing cancer cells with fewer toxic side effects

Researchers have engineered gold-based molecules that target cancer cells and leave healthy cells unharmed, in a critical step towards precision cancer drugs with fewer toxic side effects.

6 Sep 2019

Benefits of restarting blood thinners outweigh the gastrointestinal‐related risks

Anticoagulants and antiplatelet drugs, which are blood thinners such as warfarin and aspirin, are commonly taken to reduce the risk of potentially fatal blood clots, but they carry an increased risk of gastrointestinal bleeding.

6 Sep 2019

Physician-hospital integration increases health care costs, study shows

When physicians integrate with hospitals, the cost of health care rises even though there's no evidence patients get better treatment, according to a new paper by experts at Rice University and Blue Cross and Blue Shield of Texas.

6 Sep 2019

VUMC partners with Batavia to move promising Zika antibody therapy closer to the clinic

Researchers at Vanderbilt University Medical Center are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.

6 Sep 2019

Mesh electronics could make brain stimulation the new therapeutic norm

Implantable brain electrodes have been around for quite some time now, both for diagnosing and treating neuropsychiatric conditions like Parkinson’s disease. However, one limitation of conventional probes is their size and rigidity, compared to the soft, gelatinous consistency of the brain.

6 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Thames typical of superbug-breeding rivers, says new study

The River Thames is rapidly becoming a breeding pool for antibiotic-resistant bacteria, according to a new study, which underlines the urgent need to cut down the amount of antibiotics currently being discharge into the river by at least 80% to arrest this trend.

5 Sep 2019

Zika virus damages the adult human brain and impairs memory in mouse model

Zika virus attracted worldwide attention in recent years due to the devastating consequences of infection for pregnant women and their fetuses, many of which were born with microcephaly and other severe neurological malformations.

5 Sep 2019

School districts double down on drug testing, targeting even middle schoolers

Thirteen-year-old Aura Brillhart and her 11-year-old sister, Morgan, will face a new sort of test in school this year: a drug test.

5 Sep 2019

Cancer patients with low income and no insurance see fewer trial benefits

When it comes to benefiting from experimental treatments offered in cancer clinical trials, your health insurance status and where you live matters, according to results of two new research studies to be presented at the 2019 ASCO Quality Care Symposium, held September 6 and 7 in San Diego.

5 Sep 2019

Opioids after surgery overly prescribed in USA and Canada

A new study covering several institutions shows that patients recovering from surgery in the US or Canada have a 50% chance of being treated with opioids. This is seven times as high as the corresponding percentage in Sweden. Within the US, the initial dosages are likely to be over 200 morphine milligram equivalents (MME) – much more than in Canada.

5 Sep 2019

New polypill cheaper, better at reducing cardiovascular disease

A new study from Beth Israel Deaconess Medical Center (BIDMC) has proved the cost-effectiveness and life-saving potential of the “polypill”: a single new pill which combines four commonly prescribed cardiovascular drugs into one to prevent a recurrent stroke or heart event in adult patients in low- and middle-income countries (LMIC).

5 Sep 2019

Common IBD drugs not linked to increased risk of serious infections in children

In a new register-based study, Swedish and Danish researchers show that common drugs for Inflammatory Bowel Disease, so-called TNF-α inhibitors, are not linked to increased risk of serious infections in children. Previous studies have shown an increased risk in corresponding adult patients.

5 Sep 2019