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SLU study to use various assays for new TB vaccine development

A pilot study at Saint Louis University Center for Vaccine Development could shape the future of tuberculosis vaccine research by developing tests to identify the most promising vaccine candidates to address this global health crisis.

29 Nov 2012

Periodontal disease identified using salivary biomarkers

Markers of inflammation found in saliva could be used to identify periodontal disease in large epidemiologic surveys, avoiding the need for cumbersome and expensive tests, suggest researchers.

29 Nov 2012

Mental health amongst top reasons why young people attend GPs in Mid West Ireland

A recent study of primary care support for youth mental health in the Mid West was undertaken by researchers at the Centre for Interventions in Infection, Inflammation & Immunity (4i), Graduate Entry Medical School, UL (www.4i.ie). The researchers surveyed physicians in Limerick, Clare, and North Tipperary and found mental health and family conflict represented the most frequent reasons why young people attended GPs.

29 Nov 2012

Microglia might play a key role in protecting brain from Alzheimer's

A new experimental study carried out in mice shows that microglia, immune cells of the brain, might play a key role in protecting the brain from Alzheimer's disease (AD).

29 Nov 2012

Review: Omega-3 fatty acids may still help prevent heart disease

Literally hundreds of clinical trials, including some that have gained widespread attention, have been done on the possible benefits of omega-3 fatty acids for the prevention of heart disease - producing conflicting results, varied claims, and frustrated consumers unsure what to believe.

29 Nov 2012

IL17RC-mediated immune responses can be crucial in causing AMD

Changes in how genes in the immune system function may result in age-related macular degeneration (AMD), the leading cause of visual impairment in older adults, based on preliminary research conducted by National Institutes of Health (NIH) investigators.

29 Nov 2012

NovImmune commences NI-0101 Phase I clinical trial in arthritis

NovImmune SA initiated dosing in a Phase I clinical trial of NI-0101, a monoclonal antibody drug candidate targeting toll-like receptor-4 (TLR4).

29 Nov 2012

Researchers aim to improve feeling of 'walking on marbles' for arthritis patients

Researchers at the University of Southampton are to undertake a new stage of a study aimed at improving the health and mobility of those suffering from the common complaint of 'walking on marbles' associated with Rheumatoid Arthritis (RA) in the feet.

28 Nov 2012

High-resolution real-time images show how nerves may be damaged during earliest stages of MS

High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.

28 Nov 2012

Brain microhemorrhages more common among high altitude cerebral edema survivors

New magnetic resonance imaging (MRI) research shows that mountain climbers who experience a certain type of high altitude sickness have traces of bleeding in the brain years after the initial incident, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

28 Nov 2012

Young vascular systems adapt to obesity

Researchers have identified physiologic changes in the vascular systems of children that appear to be an adaptive response to obesity.

27 Nov 2012

Leading urologic oncologist explains bladder cancer basics

An unhappy bladder won't be ignored. Frequent urination, pain while urinating, burning while urinating, blood in the urine, and even back pain or pelvic pain can all be symptoms of bladder cancer or other urinary tract problems. The trick, however, is that the absence of urinary symptoms doesn't guarantee a healthy bladder.

27 Nov 2012

Johns Hopkins receives $1.9M NIH grant to establish new center for sleep research

More than one-quarter of the adult population of the U.S. suffers from sleep disturbances known to contribute to life-threatening illnesses such as cardiovascular disease, diabetes, and dementia as well as depression, chronic pain, and fatigue. Often such sleeplessness is a consequence of obesity, lifestyle, and work.

27 Nov 2012

First evidence of blood vessel dysfunction found in healthy young people with cystic fibrosis

The first evidence of blood vessel dysfunction has been found in a small cohort of generally healthy young people with cystic fibrosis, researchers report.

26 Nov 2012

Weight loss and quality of sleep: an interview with Kerry Stewart

In our particular study we used a survey which consisted of 50 different questions which get at different aspects of sleep health. It was a patient self-report.

26 Nov 2012

Smoking-related diabetes a modifiable risk factor

Cigarette smoking is a modifiable risk factor for impaired insulin secretion in Japanese men, show study findings.

23 Nov 2012

Smoking-related diabetes a modifiable risk factor

Cigarette smoking is a modifiable risk factor for impaired insulin secretion in Japanese men, show study findings.

23 Nov 2012

Electronic device sniffs out sleep apnea syndrome

An electronic nose could be used to diagnose obstructive sleep apnea syndrome, by detecting the presence of volatile organic molecules in the breath of a patient, research suggests.

22 Nov 2012

Scientists discover telomerase as cause of chronic inflammation in human cancers

A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodegenerative diseases, and metabolic diseases such as diabetes.

22 Nov 2012

Rituximab may help patients with aPL-related clinical problems

Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies (aPLs) who suffer from aPL-related clinical problems that do not respond to anticoagulation, such as cardiac disease and kidney disease, according to a new study by rheumatology researchers at Hospital for Special Surgery. The study appears online ahead of print, in the journal Arthritis and Rheumatism.

21 Nov 2012