Atherosclerosis News and Research

RSS

Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Cleveland Clinic researchers elected as AAAS Fellows for excellent contributions to science

Cleveland Clinic researchers Richard A. Padgett, Ph.D., and Edward F. Plow, Ph.D., have been named Fellows of the American Association for the Advancement of Science (AAAS). This year's AAAS Fellows will be formally announced in the AAAS News & Notes section of the journal Science on Nov. 29, 2013.

26 Nov 2013

CVD expert requests Mexican government to carry out mandatory screening for 18-year-olds

A cardiovascular disease expert is calling for mandatory screening of 18 year-old Mexicans to halt the CVD epidemic plaguing the nation. Cardiovascular risk factors will be a key theme at the Mexican Congress of Cardiology, held 23 to 27 November in Leon, Guanajuato, Mexico. The Congress is organised by the Mexican Society of Cardiology and features a collaborative programme with the European Society of Cardiology.

23 Nov 2013

Targeting single enzyme in the obese could help prevent and treat diabetes

A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to mouse studies done by researchers at Columbia University Medical Center. The findings were published today in the online edition of Cell Metabolism.

22 Nov 2013

Study identifies possible link between orthostatic hypotension and atrial fibrillation

Results of a Johns Hopkins-led study have identified a possible link between a history of sudden drops in blood pressure and the most common form of irregular heartbeat.

21 Nov 2013

UCP1 protein helps fight against obesity

The uncoupling Protein 1 (UCP1) is found exclusively in brown adipose tissue. Until some years ago it was thought that only babies and hibernating animals had brown adipose tissue, but since then it also has been found in adults, so UCP1 could be useful in the fight against obesity.

20 Nov 2013

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Patients with acute coronary syndrome who were treated with the experimental drug varespladib were more likely to experience additional cardiovascular events - including sudden death, heart attack and stroke - than those treated with placebo, according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C5Research).

19 Nov 2013

Study: Blood cell growth factor improves effects of exercise in patients with peripheral artery disease

A blood cell growth factor can boost the effects of exercise in improving mobility for patients with peripheral artery disease, a clinical study has shown.

19 Nov 2013

Grave prognosis for heart patients with treatment-resistant hypertension

Patients with coronary artery disease have a particularly high risk for poor outcomes if they have treatment-resistant hypertension, shows an analysis of the Treating to New Targets trial.

18 Nov 2013

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Global Genomics Group and Metabolon today announced that they have entered into a collaboration agreement to investigate biological networks and pathways in order to discover novel biomarkers and pharmaceutical targets for cardiovascular diseases.

15 Nov 2013

TGen-led study reveals viable target to prevent spread of brain cancer

A cellular pathway interaction known as TWEAK-Fn14, often associated with repair of acute injuries, also is a viable target for drug therapy that could prevent the spread of cancer, especially brain cancer, according to a study led by the Translational Genomics Research Institute.

11 Nov 2013

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

Despite high expectations for the commonly used diabetes drug metformin to improve risk factors for heart disease in people without diabetes, few beneficial effects have been found in a randomised trial of patients with established cardiovascular disease, published in The Lancet Diabetes & Endocrinology.

7 Nov 2013

Genkyotex announces initiation of GKT137831 Phase II study in patients with diabetic nephropathy

Genkyotex, the leading developer of selective NOX enzyme inhibitors, announced today the initiation of a multinational Phase II clinical study of GKT137831 in patients with diabetic nephropathy.

5 Nov 2013

Taking care of your gums by brushing could help hold heart disease at bay

Taking care of your gums by brushing, flossing, and regular dental visits could help hold heart disease at bay. Researchers at Columbia University's Mailman School of Public Health have shown for the first time that as gum health improves, progression of atherosclerosis slows to a clinically significant degree. Findings appear online in the Journal of the American Heart Association.

3 Nov 2013

"Good" cholesterol improves blood glucose levels, say scientists

High density lipoprotein cholesterol (HDL), the so-called "good" cholesterol improves blood glucose levels by enhancing skeletal muscle function and reducing adiposity, scientists of the Helmholtz Zentrum München report in the current issue of the renown American Heart Association Journal ‚Circulation'.

31 Oct 2013

HIV infection, not antiretroviral therapy associated with risk for atherosclerosis

HIV infection, not antiretroviral therapy (ART), is associated with risk for atherosclerosis in patients with no history of smoking, particularly those infected for eight years or more.

31 Oct 2013

HDL-like particles could someday be used to combat atherosclerosis

A new type of "good cholesterol," made in the lab, could one day deliver drugs to where they are needed in the body to treat disease or be used in medical imaging, according to scientists.

30 Oct 2013

Early detection of heart disease opens up important possibilities of preventing late disease

Heart disease remains the number one cause of early disability and death in the western world and now, surprisingly, has also become the most frequent cause of early death in the developing world.

30 Oct 2013

Stroke prevention study: Medication plus lifestyle changes safe, effective than surgical interventions

The final results of a stroke prevention study in patients with narrowed brain arteries confirm earlier findings: Medication plus lifestyle changes are safer and more effective at preventing stroke than a surgical technique called stenting.

28 Oct 2013

Healthy weight: The key to a healthy heart

A healthy weight is the key to a healthy heart, and yet an estimated 1 out of 3 children is either overweight or obese in the U.S. During a special symposium Oct. 27 at the American Academy of Pediatrics National Conference and Exhibition in Orlando, pediatricians discussed obesity and cardiovascular risk factors, public health policy, and how physicians can partner with families to improve children's weight.

28 Oct 2013

International researchers identify 11 new genes linked to Alzheimer's disease

An international group of researchers has identified 11 new genes that offer important new insights into the disease pathways involved in Alzheimer's disease. The highly collaborative effort involved scanning the DNA of over 74,000 volunteers-the largest genetic analysis yet conducted in Alzheimer's research-to discover new genetic risk factors linked to late-onset Alzheimer's disease, the most common form of the disorder.

28 Oct 2013

Atherosclerosis News and Research

Further Reading

Cleveland Clinic researchers elected as AAAS Fellows for excellent contributions to science

CVD expert requests Mexican government to carry out mandatory screening for 18-year-olds

Targeting single enzyme in the obese could help prevent and treat diabetes

Study identifies possible link between orthostatic hypotension and atrial fibrillation

UCP1 protein helps fight against obesity

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Study: Blood cell growth factor improves effects of exercise in patients with peripheral artery disease

Grave prognosis for heart patients with treatment-resistant hypertension

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

TGen-led study reveals viable target to prevent spread of brain cancer

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

Genkyotex announces initiation of GKT137831 Phase II study in patients with diabetic nephropathy

Taking care of your gums by brushing could help hold heart disease at bay

"Good" cholesterol improves blood glucose levels, say scientists

HIV infection, not antiretroviral therapy associated with risk for atherosclerosis

HDL-like particles could someday be used to combat atherosclerosis

Early detection of heart disease opens up important possibilities of preventing late disease

Stroke prevention study: Medication plus lifestyle changes safe, effective than surgical interventions

Healthy weight: The key to a healthy heart

International researchers identify 11 new genes linked to Alzheimer's disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News