Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Study finds sex-based differences in genetic risk factors for developing gliomas

Glioma is the most common type of primary malignant brain tumor in the United States; glioblastoma being the most common type of glioma in adults.

29 Jun 2018

Human leukemia virus increases disease risk by changing the way DNA loops inside our cells

A human virus that causes a rare form of leukemia increases the risk of disease by changing the way DNA loops inside our cells.

29 Jun 2018

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Researchers at Indiana University have found early evidence that tiny snippets of genetic material called microRNA may help with early detection of conditions such as Alzheimer's disease.

29 Jun 2018

Female bladder bacteria found to be similar to microbes in the vagina

Scientists and physicians at Loyola University Chicago and Loyola Medicine were the first to publish groundbreaking research that debunked the common belief that urine in healthy women is sterile.

28 Jun 2018

UPMC and Pitt announce launch of advanced genome sequencing center

UPMC and the University of Pittsburgh today announced the launch of an advanced genome sequencing center to support clinical diagnostics and research initiatives in precision medicine and immunotherapy.

27 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

Researchers identify novel mutation in amyloid diseases

Researchers have identified a one-of-a kind mutation in the DNA of a patient who died of transthyretin (TTR) amyloidosis, a progressive condition characterized by the buildup of abnormal deposits of a misfolded protein called amyloid in the body's organs and tissues.

26 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

A Delaware team including Erin Crowgey, PhD, associate director of Bioinformatics with Nemours Biomedical Research, has published a study in the peer-reviewed journal BMC Bioinformatics, showing that DNA patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients.

22 Jun 2018

Researchers diagnose cerebral palsy using AI and next-generation sequencing

Researchers have shown that patients with spastic cerebral palsy (CP) can be identified using DNA methylation patterns in circulating blood cells.

22 Jun 2018

Harnessing Pediatric Cancer Genomic Data in the Cloud

Dr. Jinghui Zhang, an esteemed computational biologist at St. Jude Children's Research Hospital discusses her latest study and how technology such as cloud computing is changing the way that scientists carry out research.

21 Jun 2018

New computational method identifies molecular signatures that distinguish individuals

EMBL researchers have designed a computational method to jointly analyze multiple types of molecular data from patients in order to identify molecular signatures that distinguish individuals.

21 Jun 2018

Targeting cells involved in blood vessel formation could hinder brain tumor growth

A type of highly malignant brain tumor contains a large number of cells involved in the formation of new blood vessels, helping it proliferate and spread.

20 Jun 2018

Study opens new potential avenue for treating ovarian cancer

Researchers at Houston Methodist Research Institute and The University of Texas MD Anderson Cancer Center have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium deficiency and kidney diseases, may increase the likelihood of surviving ovarian cancer.

14 Jun 2018

Cleveland Clinic receives $3.7 million grant from AHA for atrial fibrillation research

The American Heart Association has awarded Cleveland Clinic a $3.7 million grant for atrial fibrillation research. The four-year, competitive award will support three synergistic projects aimed at improving outcomes for patients with atrial fibrillation, a common heart rhythm abnormality.

13 Jun 2018

Study: Aircraft microbiomes have much in common with those at homes and offices

What does flying in a commercial airliner have in common with working at the office or relaxing at home?According to a new study, the answer is the microbiome - the community of bacteria found in homes, offices and aircraft cabins.

8 Jun 2018

DHS accelerates development of new methods to detect emerging biothreats

Biothreats - harmful pathogens that are either naturally or deliberately released - pose a risk to national security and public health, and identifying new detection methods is a top priority for the Department of Homeland Security (DHS) Science and Technology Directorate.

8 Jun 2018

International 'A' team unveils new glioblastoma atlas

It takes an "A" team to make headway against glioblastoma, a highly aggressive type of brain cancer. Glioblastoma is the most common type of malignant brain tumor in adults. In addition to the caliber of the researchers involved, in this case "A" also stands for atlas.

6 Jun 2018

Disintegrating brain lesions could predict disease progression in MS patients

For decades, clinicians treating multiple sclerosis have interpreted the appearance of new or expanding brain lesions on magnetic resonance imaging scans as a sign that a patient's disease is getting worse.

5 Jun 2018

Bioinformatics News and Research

Further Reading

Study finds sex-based differences in genetic risk factors for developing gliomas

Human leukemia virus increases disease risk by changing the way DNA loops inside our cells

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Female bladder bacteria found to be similar to microbes in the vagina

UPMC and Pitt announce launch of advanced genome sequencing center

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

Researchers identify novel mutation in amyloid diseases

Researchers discover immune profile for effective cancer immunotherapy

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

Researchers diagnose cerebral palsy using AI and next-generation sequencing

Harnessing Pediatric Cancer Genomic Data in the Cloud

New computational method identifies molecular signatures that distinguish individuals

Targeting cells involved in blood vessel formation could hinder brain tumor growth

Study opens new potential avenue for treating ovarian cancer

Cleveland Clinic receives $3.7 million grant from AHA for atrial fibrillation research

Study: Aircraft microbiomes have much in common with those at homes and offices

DHS accelerates development of new methods to detect emerging biothreats

International 'A' team unveils new glioblastoma atlas

Disintegrating brain lesions could predict disease progression in MS patients

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