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Mutation in BRCA1 tumor suppressor gene helps develop breast, ovarian cancer: Study

Studies have well established that women who harbor a mutation in the BRCA1 tumor suppressor gene are at greater risk for developing breast and ovarian cancers. Less known is information on other molecular events that may impact cancer formation in cells having a BRCA1 mutation. Investigators from The Cancer Institute of New Jersey and a number of major cancer centers in Europe have identified the role a key protein plays in helping cells with mutant BRCA1 genes to survive.

20 May 2010

New study shows CDPK1 controls toxoplasma's ability to secrete microneme proteins

Researchers at Washington University School of Medicine in St. Louis have identified a parasite protein that has all the makings of a microbial glass jaw: it's essential, it's vulnerable and humans have nothing like it, meaning scientists can take pharmacological swings at it with minimal fear of collateral damage.

20 May 2010

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.

20 May 2010

Gene therapy shows positive effects in rat models of PAH: Researchers

Gene therapy has been shown to have positive effects in rat models of pulmonary arterial hypertension, according to researchers at the University of Adelaide in Australia.

20 May 2010

Plastic corneal prosthesis for patients unable to tolerate donor corneas

For many patients who become blind after an accident or illness, a corneal transplantation could restore the ability to see. Each year, 40,000 people in Europe - in Germany, about 7,000 - await the opportunity to be able to see again, thanks to cornea donors. But donor corneas are not common. Dr. Joachim Storsberg of the Fraunhofer Institute for Applied Polymer Research IAP in Potsdam-Golm developed material and production process for a corneal prosthesis made of plastic.

19 May 2010

Promosome signs technology license and partnership agreement with Recopharma AB of Stockholm

Promosome LLC, a biotechnology company uniquely dedicated to the development of technologies related to the regulation of protein synthesis through translation initiation, today announced the signing of a technology license and partnership agreement with Recopharma AB of Stockholm, Sweden. Recopharma is a recognized leader in the research and development of therapeutic recombinant mucin-type fusion proteins.

19 May 2010

BBSRC, EPSRC fund £1.5M for synthetic biology projects under EuroSYNBIO Programme

Four new projects, announced today, will develop biological methods that offer a new approach to antibiotic production, power generation for extremely small mechanical components, new classes of medicines and innovative techniques to study cell biology.

19 May 2010

Alternaria fungus produces more spores with increase in CO2 levels and makes life miserable for allergy, asthma sufferers

A new study of the relationship between carbon dioxide levels and plant growth suggests for the first time that not only do plants grow bigger and produce more pollen when exposed to higher levels of the greenhouse gas, CO2, but the common, allergen-producing fungus Alternaria alternate produces three times more spores when feeding on those enriched plants. The spores disperse on the wind, making allergies and asthma symptoms worse.

19 May 2010

Study confirms low levels of serotonin transporter in cerebral cortex of chronic ecstasy users

Levels of the serotonin transporter are low in the brains of users of ecstasy, according to a US National Institute of Drug Abuse-funded study by Toronto's Centre for Addiction and Mental Health (CAMH) and The Hospital for Sick Children (SickKids) published today in the journal Brain.

19 May 2010

Studies suggest potent therapeutic effects of rufinamide in bipolar disorder, depressive and anxiety disorders

This study formulates the hypothesis that rufinamide, a drug so far used against epilepsy, may also be effective in bipolar disorder, depressive and anxiety disorders, panic disorder and obsessive-compulsive disorder, eating disorders, and substance use disorders. It is just an hypothesis based on two cases that needs to be confirmed by specific studies.

19 May 2010

Researchers develop PHI test to help determine aggressiveness of prostate cancer

Researchers at Johns Hopkins University have developed what could be a promising new test to help determine the aggressiveness of prostate cancer, says a Bay Area urologist who specializes in treating the disease, although patients may not realize any benefits for another decade or longer.

19 May 2010

Researchers identify cancer gene that could help fight paediatric glioma

Researchers have identified an important cancer gene that could lead to more effective drugs being developed to fight paediatric high grade glioma, a disease which currently has a poor prognosis.

19 May 2010

Generex Biotechnology's Phase I study data of AE37 for prostate cancer published

Generex Biotechnology Corporation announced today publication of results from the first Phase I study of its lead immunotherapeutic agent AE37 in patients with prostate cancer. At the end of 2009, the Company announced positive interim results from a Phase II trial being conducted with AE37 in patients with breast cancer. The compound is being developed by its wholly-owned subsidiary, Antigen Express, Inc.

19 May 2010

Researchers discover biological pathway signature of ccRCC

By examining expression of every human gene in clear cell renal cell carcinoma compared to normal kidney cells, researchers at Mayo Clinic's campus in Florida have discovered gene signatures they say explain much of the biology of this common and difficult-to-treat kidney cancer.

19 May 2010

KTH Royal Institute of Technology Stockholm, BioSilta Oy collaborate to optimise protein screening

KTH Royal Institute of Technology Stockholm and Biotechnology start-up BioSilta Oy of Oulu Finland have been collaborating over the last year to optimise protein screening in a range of microwell plate formats. The technique utilises EnBase Flo the newly developed Enzymatic Release media technology from BioSilta.

18 May 2010

VBI researchers establish new tree of life for gamma-proteobacteria

A new "tree of life" has been constructed by researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech for the gamma-proteobacteria, a large group of medically and scientifically important bacteria that includes Escherichia coli, Salmonella typhimurium, and other disease-causing organisms.

18 May 2010

United Natural Foods to distribute Glow Gluten Free Cookies

Regi and Jill Brack, the husband/wife team behind Glow Gluten Free Cookies have announced that their four flavors of gluten free, wheat free and casein free cookies will now be distributed by United Natural Foods, Inc. the leading independent national distributor of natural, organic and specialty foods in the United States.

18 May 2010

Scientists discover prothymosin-alpha protein to control HIV and other infections

Scientists at Duke University Medical School and Mount Sinai School of Medicine have found a new role for a host protein that provides further insight into how CD8+ T cells work to control HIV and other infections. Study authors say the finding may yield new strategies for prevention or treatment.

18 May 2010

NMES may reduce muscle atrophy in patients with severe COPD: Researchers

Neuromuscular electrical stimulation may reduce muscle atrophy in patients with severe chronic obstructive pulmonary disease, according to Canadian researchers.

18 May 2010

Tests of kidney function, damage predict risk of death from cardiovascular diseases: Study

Common tests of kidney function and damage predict the risk of death from cardiovascular diseases and all causes, according to a paper from the Chronic Kidney Disease Prognosis Consortium, established last year by Kidney Disease: Improving Global Outcomes.

18 May 2010

G Protein News and Research

Mutation in BRCA1 tumor suppressor gene helps develop breast, ovarian cancer: Study

New study shows CDPK1 controls toxoplasma's ability to secrete microneme proteins

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Gene therapy shows positive effects in rat models of PAH: Researchers

Plastic corneal prosthesis for patients unable to tolerate donor corneas

Promosome signs technology license and partnership agreement with Recopharma AB of Stockholm

BBSRC, EPSRC fund £1.5M for synthetic biology projects under EuroSYNBIO Programme

Alternaria fungus produces more spores with increase in CO2 levels and makes life miserable for allergy, asthma sufferers

Study confirms low levels of serotonin transporter in cerebral cortex of chronic ecstasy users

Studies suggest potent therapeutic effects of rufinamide in bipolar disorder, depressive and anxiety disorders

Researchers develop PHI test to help determine aggressiveness of prostate cancer

Researchers identify cancer gene that could help fight paediatric glioma

Generex Biotechnology's Phase I study data of AE37 for prostate cancer published

Researchers discover biological pathway signature of ccRCC

KTH Royal Institute of Technology Stockholm, BioSilta Oy collaborate to optimise protein screening

VBI researchers establish new tree of life for gamma-proteobacteria

United Natural Foods to distribute Glow Gluten Free Cookies

Scientists discover prothymosin-alpha protein to control HIV and other infections

NMES may reduce muscle atrophy in patients with severe COPD: Researchers

Tests of kidney function, damage predict risk of death from cardiovascular diseases: Study

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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