Immune System News and Research

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AAPM commends FDA’s move to introduce labeling changes on ER/LA opioids

The physicians of the American Academy of Pain Medicine (AAPM) hailed long-awaited labeling changes and other steps taken by the U.S. Food and Drug Administration (FDA) last week to enhance safety in the prescribing of extended-release and long-acting (ER/LA) opioids.

18 Sep 2013

Children with 22q11.2 deletion syndrome may often be misdiagnosed to have autism

Children with a genetic disorder called 22q11.2 deletion syndrome, who frequently are believed to also have autism, often may be misidentified because the social impairments associated with their developmental delay may mimic the features of autism, a study by researchers with the UC Davis MIND Institute suggests.

18 Sep 2013

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

Researchers from the University of Chicago have been awarded a five-year, $1.5 million grant from the National Institutes of Health to develop stimulated dendritic cell-derived exosomes that show remarkable promise as a treatment for multiple sclerosis and other neurological diseases involving loss of myelin, the insulation around nerve fibers.

18 Sep 2013

Coeliac disease on rise in Scots children

More children than ever before are living with a debilitating digestive disease, research has shown.

18 Sep 2013

Study: Mesenchymal stem cell transplantation may help treat stress urinary incontinence

Vaginal delivery presents the possibility of injury for mothers that can lead to "stress urinary incontinence", a condition affecting from four to 35 percent of women who have had babies via vaginal delivery. Many current treatments, such as physiotherapy and surgery, are not very effective.

18 Sep 2013

Cleveland Clinic creates spin-off company to develop vaccine for preventing breast cancer

Cleveland Clinic Innovations has created a spin-off company to develop a preventive breast cancer vaccine based on research from Cleveland Clinic's Lerner Research Institute.

18 Sep 2013

Researchers identify starting points for preventing diarrheal disease outbreaks in remote Africa

Using a simple survey tool, a team of researchers has done what complex studies have failed to do -- provide data that identifies starting points for preventing diarrheal disease outbreaks in at least one region of Africa.

18 Sep 2013

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy.

18 Sep 2013

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17 Sep 2013

Researchers discover how Yersinia immobilizes immune system to spread within organs

Researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have identified how one type of bacteria, Yersinia, immobilizes the immune system in order to grow in the organs of mice. To do so, the researchers extended the use of a technique and suggest that it could be used to study other bacteria that use the same or similar means of infection.

17 Sep 2013

New method to target, eliminate cancer-supporting macrophages in mouse tumors

When a person has cancer, some of the cells in his or her body have changed and are growing uncontrollably. Most cancer drugs try to treat the disease by killing those fast-growing cells, but another approach called immunotherapy tries to stimulate a person's own immune system to attack the cancer itself.

17 Sep 2013

Immune marker predicts transplant success, improves selection of bone marrow donors

The risk of death following bone marrow transplantation can be reduced about 60 percent using a new technique to identify bone marrow donors who make the most potent cancer-fighting immune cells, according to research from St. Jude Children's Research Hospital. The findings appear in the September 16 online issue of the Journal of Clinical Oncology.

17 Sep 2013

arGEN-X announces CTA filing of Phase Ib cancer study with ARGX-111

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces today the CTA filing of a first-in-man Phase Ib cancer study with ARGX-111, its second proprietary SIMPLE Antibody product to enter the clinic this year.

17 Sep 2013

Research finding offers new approach to treating melanoma

Scientists at Sanford-Burnham Medical Research Institute today announced the discovery that a gene encoding an enzyme, phosphoinositide-dependent kinase-1, plays an essential role in the development and progression of melanoma. The finding offers a new approach to treating this life-threatening disease.

17 Sep 2013

Understanding essential role of gut microbes in immune system

A new understanding of the essential role of gut microbes in the immune system may hold the key to dealing with some of the more significant health problems facing people in the world today, Oregon State University researchers say in a new analysis.

17 Sep 2013

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.

17 Sep 2013

Researchers identify new link between meal times and daily changes in immune system

A new link between meal times and daily changes in the immune system has been identified by UC San Francisco researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.

17 Sep 2013

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Vanderbilt's Eskind Diabetes Clinic has been selected to examine the ability of the drug abatacept to prevent type 1 diabetes (T1D). As part of the TrialNet consortium, Vanderbilt will be one of 14 North American sites observing the effects of the drug in people at high risk to develop T1D.

17 Sep 2013

Researchers identify gene mutation linked to age-related macular degeneration

An international team of researchers, led by scientists at The Genome Institute at Washington University School of Medicine in St. Louis and the University of Michigan School of Public Health in Ann Arbor, has identified a gene mutation linked to age-related macular degeneration (AMD), the leading cause of blindness in Americans over age 50.

17 Sep 2013

Researchers find that people affected by cold sores have mutation in gene

Why some people are troubled by cold sores while others are not has finally been explained by scientists. Cold sores affect around one in five people but, until now, no one has been sure why some are more prone to the virus that causes them.

17 Sep 2013

Immune System News and Research

AAPM commends FDA’s move to introduce labeling changes on ER/LA opioids

Children with 22q11.2 deletion syndrome may often be misdiagnosed to have autism

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

Coeliac disease on rise in Scots children

Study: Mesenchymal stem cell transplantation may help treat stress urinary incontinence

Cleveland Clinic creates spin-off company to develop vaccine for preventing breast cancer

Researchers identify starting points for preventing diarrheal disease outbreaks in remote Africa

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

Improve Your Lifestyle, Lengthen Your Telomeres

Researchers discover how Yersinia immobilizes immune system to spread within organs

New method to target, eliminate cancer-supporting macrophages in mouse tumors

Immune marker predicts transplant success, improves selection of bone marrow donors

arGEN-X announces CTA filing of Phase Ib cancer study with ARGX-111

Research finding offers new approach to treating melanoma

Understanding essential role of gut microbes in immune system

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

Researchers identify new link between meal times and daily changes in immune system

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Researchers identify gene mutation linked to age-related macular degeneration

Researchers find that people affected by cold sores have mutation in gene

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