Immune System News and Research

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Smoking-cessation in HIV-positive individuals: an interview with Dr Ellen R. Gritz, University of Texas MD Anderson Cancer Center

In the general population, current smoking prevalence is 18%. Persons living with HIV/AIDS smoke at a rate 2 to 3 times higher, up to almost 70% in some studies.

16 Sep 2013

Affimed Therapeutics, LLS partner to co-fund AFM13 phase 2 trial for treatment of Hodgkin Lymphoma

Affimed Therapeutics AG and The Leukemia & Lymphoma Society today announced a partnership to co-fund a phase 2 trial with the Recruit-TandAb AFM13, a novel tetravalent bispecific antibody directed against human CD30 and CD16A in Hodgkin Lymphoma patients for whom currently available treatments have failed.

16 Sep 2013

Research findings bring scientists one step closer to preventing HIV infections

In a long-awaited finding, a team of Chinese and US scientists has determined the high-resolution atomic structure of a cell-surface receptor that most strains of HIV use to get into human immune cells. The researchers also showed where maraviroc, an HIV drug, attaches to cells and blocks HIV’s entry.

13 Sep 2013

Researchers develop new ways of preventing septic shock

The body's immune system is set up much like a home security system; it has sensors on the outside of cells that act like motion detectors — floodlights — that click on when there's an intruder rustling in the bushes, bacteria that seem suspect.

13 Sep 2013

Researchers show network of genes which enforce cooperative state within cells

We often think of human cells as tiny computers that perform assigned tasks, where disease is a result of a malfunction. But in the current issue of Science, researchers at The Mount Sinai Medical Center offer a radical view of health — seeing it more as a cooperative state among cells, while they see disease as result of cells at war that fight with each other for domination.

13 Sep 2013

Microbes living in unexpected environments can generate highly toxic methylmercury

Microbes that live in rice paddies, northern peat bogs and other previously unexpected environments are among the bacteria that can generate highly toxic methylmercury, researchers at Oak Ridge National Laboratory and the Smithsonian Environmental Research Center have learned.

13 Sep 2013

TreatFOOD research project develops food supplements to relieve malnutrition

Thirty-three million children worldwide suffer from moderate acute malnutrition. It affects human development and generally, increases susceptibility to illness. Unfortunately, the nutritional supplements and aid that these children may receive today is based upon dated standards developed for adults or otherwise intended for children with severe acute nutrition.

13 Sep 2013

Data can help scientists, physicians match precision drugs to cancer's genetic traits

More than 5,000 genetic profiles of tumor DNA have been completed in a large research study by scientists at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Boston Children's Hospital designed to speed the development of personalized cancer care with precision treatments.

13 Sep 2013

Study: Higher rates of acute hepatitis C virus clearance are seen in women

A study of patients infected with acute hepatitis C virus (HCV) infection found that women had higher rates of spontaneous viral clearance—undetectable levels of the virus without initiating drug therapy.

13 Sep 2013

Helper T cells important for AIDS vaccine development

A major new finding that will significantly advance efforts to create the world's first antibody-based AIDS vaccine was published today by researchers from the La Jolla Institute for Allergy and Immunology.

13 Sep 2013

Microbiologist finds breakthrough herbal medicine treatment for common human fungal pathogen

A Kansas State University microbiologist has found a breakthrough herbal medicine treatment for a common human fungal pathogen that lives in almost 80 percent of people.

13 Sep 2013

Scientists uncover how bacterium responsible for periodontal disease worsens RA

Does gum disease indicate future joint problems? Although researchers and clinicians have long known about an association between two prevalent chronic inflammatory diseases - periodontal disease and rheumatoid arthritis - the microbiological mechanisms have remained unclear.

13 Sep 2013

Surgeons must balance research and medical training with outstanding patient care

Like a juggler keeping multiple plates in the air, a surgeon in academic medicine must balance research and medical training with outstanding patient care. Charles Bellows, MD, FACS, relishes the challenge. Dr. Bellows, a University of New Mexico Professor of General Surgery, recently assumed the role of Chief of the Division of General Surgery in the Department of Surgery at the UNM School of Medicine.

12 Sep 2013

Proper precautions may help people with allergies enjoy the beautiful fall weather

As summer comes to a close, kids head back to school and preparation for fall begins, don't' forget to consider fall allergies. An estimated 35 million Americans suffer from allergies, which in the fall begin in late August and peak in September. For those with fall allergies, three triggers typically occur - ragweed, indoor allergens and infections.

12 Sep 2013

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

The ability to visualize and analyze the spread of viral infections in primary and metastatic tumors is an essential component in characterizing the therapeutic efficacy of oncolytic viruses.

12 Sep 2013

New HIV/AIDS vaccine candidate appears to clear AIDS-causing virus from body

An HIV/AIDS vaccine candidate developed by researchers at Oregon Health & Science University appears to have the ability to completely clear an AIDS-causing virus from the body.

12 Sep 2013

New antibody could prevent Candida infections in patients who receive central lines

A team of researchers at Cincinnati Children's Hospital Medical Center has developed an antibody that could prevent Candida infections that often afflict hospitalized patients who receive central lines.

12 Sep 2013

Research: New pathway plays role in fighting gut infection

The researchers found virulent E. coli bacteria blocked a pathway that would normally protect the gut from infection. These infections are particularly serious in young children and can result in diarrhoea and other complications such as kidney damage.

12 Sep 2013

Kiadis five-year follow-up phase I/II clinical study confirms long-term safety, efficacy of ATIR

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, announced today that the five-year follow-up of patients with high-risk malignancies from its Phase I/II clinical study confirms long-term safety and efficacy of ATIR™ over a broad dose range.

12 Sep 2013

Study suggests new path to make protective malaria vaccine

This study suggests that genetically engineered malaria parasites that are stunted through precise gene deletions (genetically attenuated parasites, or "GAP") could be used as a vaccine that protects against malaria infection. This means that the harmless (attenuated) version of the parasite would interact with the body in the same way as the infective version, but without possibility of causing disease.

11 Sep 2013

Immune System News and Research

Smoking-cessation in HIV-positive individuals: an interview with Dr Ellen R. Gritz, University of Texas MD Anderson Cancer Center

Affimed Therapeutics, LLS partner to co-fund AFM13 phase 2 trial for treatment of Hodgkin Lymphoma

Research findings bring scientists one step closer to preventing HIV infections

Researchers develop new ways of preventing septic shock

Researchers show network of genes which enforce cooperative state within cells

Microbes living in unexpected environments can generate highly toxic methylmercury

TreatFOOD research project develops food supplements to relieve malnutrition

Data can help scientists, physicians match precision drugs to cancer's genetic traits

Study: Higher rates of acute hepatitis C virus clearance are seen in women

Helper T cells important for AIDS vaccine development

Microbiologist finds breakthrough herbal medicine treatment for common human fungal pathogen

Scientists uncover how bacterium responsible for periodontal disease worsens RA

Surgeons must balance research and medical training with outstanding patient care

Proper precautions may help people with allergies enjoy the beautiful fall weather

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

New HIV/AIDS vaccine candidate appears to clear AIDS-causing virus from body

New antibody could prevent Candida infections in patients who receive central lines

Research: New pathway plays role in fighting gut infection

Kiadis five-year follow-up phase I/II clinical study confirms long-term safety, efficacy of ATIR

Study suggests new path to make protective malaria vaccine

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