Inflammation News and Research

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MRI lesions match site of recent-onset inflammatory back pain

Patients with recent inflammatory back pain who undergo examination with magnetic resonance imaging typically show inflammation at the site of their pain, a study confirms.

3 Sep 2012

Usefulness of liver biopsy for CALI preoperative assessment questioned

Liver biopsy is not a reliable tool for preoperative assessment of chemotherapy-associated liver injuries except for steatosis, suggest study findings published in the Archives of Surgery.

3 Sep 2012

Obesity and breast cancer recurrence: an interview with Dr. Joseph Sparano

Breast cancer recurrence is a major problem after treatment of localized breast cancer. The risk of recurrence depends on several factors including the stage of presentation and the biology of the disease.

3 Sep 2012

Potential new COPD drug

A study led by researchers at Boston University School of Medicine (BUSM) has shown that a compound used in some skin creams may halt the progression of emphysema and reverse some of the damage caused by the disease. When the compound Gly-His-Lys (GHK) was applied to lung cells from patients with emphysema, normal gene activity in altered cells was restored and damaged aspects of cellular function were repaired.

1 Sep 2012

NFAT protein plays a part in development of acute pancreatitis

It is likely that the protein is also highly significant for other inflammatory diseases. The research results have been published in the American journal Gastroenterology.

1 Sep 2012

University of Leicester scientists secure funding for Exhalyzer-D to help children's breathing

University of Leicester medical scientists have secured funding for a piece of state-of-the-art equipment to help with their research into children's breathing.

1 Sep 2012

The safety of trainee surgeons: an interview with Prof Calvin Coffey

Surgical training begins at an undergraduate medical student level where students are involved in operations to a minor degree, and educated using a combination of didactic and problem-based approaches.

31 Aug 2012

Well-known protein plays central role in development of acute pancreatitis

There is now a clear target for the treatment of acute pancreatitis, according to researchers at Lund University in Sweden, who have discovered that a well-known protein plays a central role in the development of the disease. It is likely that the protein is also highly significant for other inflammatory diseases.

31 Aug 2012

Research identifies new pathway to target with anti-inflammatory drugs

Scientists' discovery of an important step in the body's process for healing wounds may lead to a new way of treating inflammation.

31 Aug 2012

Researchers identify several genetic factors linked to C-reactive protein

African Americans have higher blood levels of a protein associated with increased heart-disease risk than European Americans, despite higher "good" HDL cholesterol and lower "bad" triglyceride levels. This contradictory observation now may be explained, in part, by a genetic variant identified in the first large-scale, genome-wide association study of this protein involving 12,000 African American and Hispanic American women.

31 Aug 2012

Grb10 plays a crucial role in increasing muscle mass during development

Scientists have moved closer toward helping people grow big, strong muscles without needing to hit the weight room. Australian researchers have found that by blocking the function of a protein called Grb10 while mice were in the womb, they were considerably stronger and more muscular than their normal counterparts.

31 Aug 2012

Chronic nerve pain: an interview with Professor Sally Lawson

Chronic nerve pain results from pathological changes within a nerve that appear to be self-sustaining and thus the pain continues for a long time.

30 Aug 2012

UAB Center of Research Translation to improve health of patients with gout, hyperuricemia

The University of Alabama at Birmingham is establishing a Center of Research Translation to improve the health of an increasing number of patients with gout and hyperuricemia.

30 Aug 2012

UH pharmacologist examines age-related oxidative, inflammatory stress

Gaining new insight to managing sodium balance and blood pressure, investigators at the University of Houston (UH) College of Pharmacy believe their work may identify future therapeutic targets to control hypertension.

30 Aug 2012

Trudeau Institute study holds promise for improved prevention and treatment of bacterial infections

New research from the laboratory of Dr. Andrea Cooper at the Trudeau Institute, just published in the European Journal of Immunology, holds promise for the improved prevention and treatment of bacterial infections and the life-threatening complications of chronic inflammation that can result from them.

29 Aug 2012

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Pulmatrix, Inc., a clinical stage biotechnology company creating novel inhaled therapeutics, announced today that three posters on its lead iCALM therapeutic, the first treatment developed utilizing its iSPERSE inhaled drug platform, will be presented at the European Respiratory Society (ERS) Annual Congress taking place September 1-5, 2012, in Vienna, Austria.

28 Aug 2012