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Supreme Court watch: Counting down to health law's historic arguments

Two years and three days after President Barack Obama signed into law a health care overhaul aimed at extending medical insurance to more than 30 million Americans, the high court begins three days of hearings over the law's validity. The challenge from 26 states and a small business group puts the court smack in the middle of a heavily partisan fight over the president's major domestic accomplishment and a presidential election campaign in which all his Republican challengers oppose the law.

26 Mar 2012

Osteoporosis researcher receives IOF Medal of Achievement

Today, at the European Congress on Osteoporosis & Osteoarthritis, Professor Cyrus Cooper was awarded the International Osteoporosis Foundation (IOF) Medal of Achievement.

26 Mar 2012

Social rejection, internalized shame may contribute to depression in lung cancer patients

Studying the role of social stigma in depression for lung cancer patients, researchers at Moffitt Cancer Center in Tampa, Fla., have found that depression can be heightened by a lung cancer patient's sense of social rejection, internalized shame and social isolation. These factors may contribute to depression at rates higher than experienced by patients with other kinds of cancer.

26 Mar 2012

Bacteriophages can tackle drug-resistant bacterial infections

Viruses that can target and destroy bacteria have the potential to be an effective strategy for tackling hard-to-treat bacterial infections. The development of such novel therapies is being accelerated in response to growing antibiotic resistance, says Dr David Harper at the Society for General Microbiology's Spring Conference in Dublin.

26 Mar 2012

Strong link between telomere shortening and heart disease risk

No one really wants the short end of the stick, in this case the short end of a chromosome. Telomeres, which are DNA-protein complexes at the ends of chromosomes, can be thought of as protein "caps" that protect chromosomes from deteriorating and fusing with neighboring chromosomes.

26 Mar 2012

Study validates Mitofusin 2 as possible target for treatment of diabetes mellitus

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have discovered that deficiency of a single protein, Mitofusin 2, in muscle and hepatic cells of mice is sufficient to cause tissues to become insensitive to insulin, thus producing an increase in blood glucose concentrations. These are the two most common conditions prior to development of diabetes type 2.

26 Mar 2012

Cathepsin Z protein regulates metastasis of pancreatic cancer

Researchers at Queen Mary, University of London have identified a new protein that makes pancreatic cancer cells less 'sticky' and therefore less able to attach to and invade other tissue.

26 Mar 2012

Diabetics less likely to survive in-hospital cardiac arrest

Patients with high blood sugar run an increased risk of dying if they have a heart attack, and diabetics are less likely to survive in-hospital cardiac arrest than non-diabetics, reveals research at the Sahlgrenska Academy, at the University of Gothenburg, Sweden.

26 Mar 2012

Obese or overweight women may have increased risk of breast cancer recurrence

Women who are overweight or obese when they are diagnosed with breast cancer are at higher risk of cancer recurrence or related death than are leaner women, according to a new study to be presented to the 8th European Breast Cancer Conference.

26 Mar 2012

Insulin resistance occurs in the brains of people with Alzheimer's

Insulin resistance in the brain precedes and contributes to cognitive decline above and beyond other known causes of Alzheimer's disease, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania. Insulin is an important hormone in many bodily functions, including the health of brain cells.

26 Mar 2012

S. gordonii may trigger infective endocarditis

Oral bacteria that escape into the bloodstream are able to cause blood clots and trigger life-threatening endocarditis. Further research could lead to new drugs to tackle infective heart disease, say scientists presenting their work at the Society for General Microbiology's Spring Conference in Dublin this week.

26 Mar 2012

New guidelines for CT-guided biopsies of lung nodules reduce radiation exposure

New guidelines for CT-guided biopsies of lung nodules significantly reduce radiation exposure allowing individuals the benefit of the procedure, which may cut down on overall lung cancer deaths.

26 Mar 2012

Metformin can have protective effects on the heart

The widely used diabetes medicine metformin can have protective effects on the heart, reveals a new study conducted at the Sahlgrenska Academy, at the University of Gothenburg, Sweden.

26 Mar 2012

Positive results from Amgen's AMG 145 Phase 1b study on patients with LDL-C

Amgen announced today positive results from a Phase 1b clinical study of AMG 145, an investigational PCSK9 inhibitor, in patients with high cholesterol who were taking statins. The study demonstrated that multiple doses of AMG 145 significantly reduced serum low density lipoprotein cholesterol (LDL-C), also known as "bad" cholesterol, by up to 81 percent versus placebo (maximum reduction) in subjects on low to moderate doses of statins/

26 Mar 2012

NSBRI, NASA's Johnson Space Center extend cooperative agreement

NASA's Johnson Space Center has awarded a five-year, $120 million extension of its cooperative agreement with the National Space Biomedical Research Institute, or NSBRI, of Houston.

26 Mar 2012

New IVIG trial can reduce OCD symptoms in children with PANDAS

Criteria for a broadened syndrome of acute onset obsessive compulsive disorder (OCD) have been proposed by a National Institutes of Health scientist and her colleagues. The syndrome, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), includes children and teens that suddenly develop on-again/off-again OCD symptoms or abnormal eating behaviors, along with other psychiatric symptoms - without any known cause.

26 Mar 2012

New UNC study estimates that 1.8B people still use unsafe water

Recent widespread news coverage heralded the success of a United Nations' goal of greatly improving access to safe drinking water around the world.

26 Mar 2012

Periodontal treatment linked with decrease in hospital admissions, medical care costs

Today, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, an abstract titled "Periodontal Therapy Reduces Hospitalizations and Medical Care Costs in Diabetics" to determine if periodontal treatment was associated with the number of hospitalizations and cost of medical care among diabetics with periodontal disease.

26 Mar 2012

New method for measurement of aggregated beta-amyloid in AD

An international team of researchers have developed a new method for measurement of aggregated beta-amyloid - a protein complex believed to cause major nerve cell damage and dysfunction in Alzheimer's disease. The new method might facilitate diagnosis and detection as well as development of drugs directed against aggregated beta-amyloid.

26 Mar 2012

GenVec announces data from respiratory syncytial virus vaccine program

GenVec, Inc. (Nasdaq: GNVC) announced today that data were presented on GenVec's respiratory syncytial virus (RSV) vaccine program at the "Keystone Symposium on Viral Immunity and Host Gene Influence", which is taking place in Keystone, Colorado from March 21-26, 2012.

26 Mar 2012