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Sygnature Discovery strengthens senior management team with appointment of Dr Paul Overton

Sygnature Discovery, a leading independent integrated drug discovery and pre-clinical solutions provider, has strengthened its senior management team with the appointment of Dr Paul Overton as Senior VP of Business Development, focusing primarily on expanding Sygnature’s North American market.

From Sygnature Discovery Limited 26 Jun 2020

Researchers identify new molecules to study specific glial cells integral to synapses

While the brain is composed of two types of cells, glia tend to receive far less attention for their importance in brain function and disease than the more celebrated neurons.

26 Jun 2020

Berkeley Lights announces Opto™ antigen-presenting bead kit to accelerate the expansion of antigen-specific T cells used to develop cell-based therapies

Berkeley Lights, Inc. today announced the Opto Antigen-Presenting Bead kit, a new reagent kit that activates and expands antigen-specific T cells in blood.

From Bruker Cellular Analysis 25 Jun 2020

Scientists create hollow, spherical sacks using protein and RNA

Using protein and RNA, scientists have created hollow, spherical sacks known as vesicles.

23 Jun 2020

St. Jude scientists create O-PDX models for pediatric brain tumor research

Scientists at St. Jude Children's Research Hospital have created orthotopic patient-derived xenograft (O-PDX) models representing a variety of pediatric brain tumor types.

23 Jun 2020

Prevention of sugar uptake can make cancer cells more sensitive to chemotherapy

By preventing sugar uptake, researchers succeeded in increasing the cancer cells' sensitivity to chemotherapeutic treatment.

23 Jun 2020

Tumor cell–based vaccine may prevent relapse of mantle cell lymphoma

A phase I/II clinical trial by researchers at Stanford University suggests that vaccines prepared from a patient's own tumor cells may prevent the incurable blood cancer mantle cell lymphoma (MCL) from returning after treatment.

22 Jun 2020

Unexpected discovery helps explain fundamental mystery about how muscles work

Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract, relax, communicate its energy needs, and adapt to exercise.

21 Jun 2020

Researchers discover new and improved way to treat poor-prognosis blood cancer

Researchers at Children's Cancer Institute have discovered what could prove a new and improved way to treat the poor-prognosis blood cancer, acute myeloid leukemia or AML.

21 Jun 2020

Overcoming leukemia treatment resistance with nanoparticle drug delivery system

UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug may be repurposed as a treatment for resurgent or chemotherapy-resistant leukemia.

18 Jun 2020

Lonza and CELLINK collaborate to advance complete 3D cell culture workflows

Lonza and the Swedish company CELLINK have partnered to offer a comprehensive 3-dimensional bioprinting solution designed to optimize and increase access to complete 3D cell culture workflows.

18 Jun 2020

Researchers call for caution of using CAR-T immunotherapy against AML

Acute myeloid leukemia is a hematological malignancy which incidence increases with age, that is biologically, phenotypically, and genetically very heterogeneous.

17 Jun 2020

Creating the first 3D neural map of a heart

News-Medical spoke to Dr. Vadigepalli and Dr. Schwaber about their groundbreaking research in which they managed to map the neurons in the heart.

15 Jun 2020

CELLINK collaborates with Lonza to advance complete 3D cell culture workflows

CELLINK has collaborated with Lonza to offer a comprehensive 3-dimensional (3D) bioprinting solution designed to advance complete 3D cell culture workflows.

From CELLINK 12 Jun 2020

WVU researchers develop new diagnostic and antibody tests for COVID-19

COVID-19 tests are in short supply. The companies that make the necessary chemicals--called reagents--can't keep up with demand. But researchers at West Virginia University are developing new tests on their own to identify who has COVID-19 now and who had it in the past but recovered.

11 Jun 2020

Study provides new evidence that liver dysfunction may lead to heart disease

A new study that looks closely at the cardiac health of flies provides new evidence that liver dysfunction may lead to deterioration of the heart.

10 Jun 2020

Study provides insight on genes present during trachea and esophagus development

A new study reporting how a network of genes directs the development of the trachea and oesophagus in mice has been published today in eLife.

9 Jun 2020

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

This spring marked a seismic shift for digestive and liver disease research at the Medical University of South Carolina with the award of more than $16.5 million in National Institutes of Health funding to open two new tightly integrated centers.

5 Jun 2020

3D facial imaging could speed diagnoses of genetic syndromes

Most children with rare genetic diseases spend years undergoing medical tests and waiting for a diagnosis -- a long, exhausting process that takes its toll on children and their families. Almost half of these children never get a definitive diagnosis.

4 Jun 2020

Exploring the molecular landscape of the aortic niche and beyond

Researchers from the group of Catherine Robin at the Hubrecht Institute characterized the molecular landscape of the aorta that supports the generation of the first Hematopoietic Stem Cells (HSCs) in the embryo.

4 Jun 2020