Clinical Trial News and Research

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Children with peanut allergy achieve tolerance with gradual peanut butter ingestion

Eating gradually increasing doses of store-bought, home-measured peanut butter for about 18 months enabled 100% of children with peanut allergy who initially could tolerate the equivalent of at least half a peanut to consume three tablespoons of peanut butter without an allergic reaction, researchers report.

10 Feb 2025

New minimally invasive treatment offers hope for primary aldosteronism

Doctors at Queen Mary University of London, Barts Health NHS Trust, and University College London have led the development of a simple, minimally invasive Targeted Thermal Therapy (Triple T) that has the potential to transform medical management of a common, but commonly overlooked, cause of high blood pressure.

10 Feb 2025

Ariceum Therapeutics receives FDA’s Orphan Drug Designation for targeted radionuclide cancer treatment

Ariceum Therapeutics (Ariceum), a private biotech company developing radiopharmaceutical products for the diagnosis and treatment of certain hard-to-treat cancers, today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to 225Ac-SSO110 (satoreotide) for the treatment of patients with Small Cell Lung Cancer (SCLC).

10 Feb 2025

Tenecteplase injection after clot removal improves stroke recovery

Removing a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in stroke survivors being more likely to have better function 90 days after their stroke than those receiving standard clot removal, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

8 Feb 2025

Clot-busting drug alteplase shows promise for stroke treatment up to 24 hours after onset

The clot-dissolving medication, alteplase, improved stroke patients' recovery by more than 50% when given up to 24 hours after the beginning of an ischemic stroke, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

8 Feb 2025

$New clinical trial aims to improve outcomes for older adults with hip fractures$

New clinical trial aims to improve outcomes for older adults with hip fractures

Hip fractures in older adults can lead to serious complications, disability and even death. Traditionally, orthopaedic surgeons have repaired a common fracture of the upper part of the thigh bone, or femur, near the hip using screws and plates to piece together slightly separated pieces of bone.

8 Feb 2025

Electronic monitoring boosts well-being and delays symptom deterioration in cancer patients

People with metastatic cancer who regularly report their symptoms via a home-based electronic monitoring system experienced improved quality of life, clinical outcomes and well-being, as well as fewer emergency department visits than those who didn't file reports.

7 Feb 2025

Mild electrical brain stimulation fails to improve motor recovery in stroke survivors

Mild electrical brain stimulation did not further improve motor recovery in stroke survivors, according to late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

7 Feb 2025

ESCAPE-MeVO trial advances understanding of stroke treatment for medium-sized vessel blockages

University of Calgary's Hotchkiss Brain Institute researchers with the Calgary Stroke Program at Foothills Medical Centre revolutionized treatment for stroke with the ESCAPE Trial, proving that a clot retrieval procedure known as endovascular thrombectomy (EVT) can dramatically improve patient outcomes after an acute ischemic stroke caused by a blockage in a large-sized blood vessel.

7 Feb 2025

Salt substitutes may lower stroke recurrence and death risk

Research indicates that salt substitutes reduce stroke recurrence and death risk, offering a safe dietary intervention for improving stroke patient outcomes.

7 Feb 2025

Fear of cancer recurrence disrupts many aspects of breast cancer survivors' lives

Breast cancer is the world's most prevalent cancer. Although earlier detection and targeted treatment have resulted in high survival rates, many breast cancer survivors experience fear of cancer recurrence. For some survivors this fear is occasional, for others it is persistent and often debilitating.

7 Feb 2025

Neoantigen vaccine sparks powerful immune defense against kidney cancer

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to long-lasting T cell expansion and no disease recurrence after 40 months.

6 Feb 2025

Testosterone found to worsen heart attack damage

Testosterone worsens the damage caused by a heart attack by increasing the number of white blood cells released from the bone marrow.

6 Feb 2025

New nasal vaccine for COVID-19 set to begin clinical trial in the U.S.

A nasal vaccine for COVID-19 – based on technology developed at Washington University in St. Louis – is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA). Ocugen, a U.S.-based biotechnology company, licensed the innovative technology from WashU in 2022.

5 Feb 2025

AI predicts effective treatment for rare disease using existing medications

After combing through 4,000 existing medications, an artificial intelligence tool helped uncover one that saved the life of a patient with idiopathic multicentric Castleman's disease (iMCD).

5 Feb 2025

Breakthrough personalized vaccine shows promising results in kidney cancer trial

Dana-Farber Cancer Institute researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune response after initiation of a personalized cancer vaccine.

5 Feb 2025

Neurostimulation improves movement in adults with spinal muscle atrophy

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease.

5 Feb 2025

Study reveals how healthy stem cells transform into cancer cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

5 Feb 2025

$USC to lead $10.8 million study on hip fracture surgery options$

USC to lead $10.8 million study on hip fracture surgery options

The University of Southern California has been approved for $10.8 million in research funding by the Patient-Centered Outcomes Research Institute (PCORI) to compare approaches to treating older adults with a fracture of the hip.

4 Feb 2025

Late menopause linked to better vascular health in women

Women who go through menopause later in life have healthier blood vessels for years to come than those who go through it earlier, according to new University of Colorado Boulder research.

4 Feb 2025

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Clinical Trial News and Research

Children with peanut allergy achieve tolerance with gradual peanut butter ingestion

New minimally invasive treatment offers hope for primary aldosteronism

Ariceum Therapeutics receives FDA’s Orphan Drug Designation for targeted radionuclide cancer treatment

Tenecteplase injection after clot removal improves stroke recovery

Clot-busting drug alteplase shows promise for stroke treatment up to 24 hours after onset

New clinical trial aims to improve outcomes for older adults with hip fractures

Electronic monitoring boosts well-being and delays symptom deterioration in cancer patients

Mild electrical brain stimulation fails to improve motor recovery in stroke survivors

ESCAPE-MeVO trial advances understanding of stroke treatment for medium-sized vessel blockages

Salt substitutes may lower stroke recurrence and death risk

Fear of cancer recurrence disrupts many aspects of breast cancer survivors' lives

Neoantigen vaccine sparks powerful immune defense against kidney cancer

Testosterone found to worsen heart attack damage

New nasal vaccine for COVID-19 set to begin clinical trial in the U.S.

AI predicts effective treatment for rare disease using existing medications

Breakthrough personalized vaccine shows promising results in kidney cancer trial

Neurostimulation improves movement in adults with spinal muscle atrophy

Study reveals how healthy stem cells transform into cancer cells

USC to lead $10.8 million study on hip fracture surgery options

Late menopause linked to better vascular health in women

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