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CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Researchers used antibody testing to predict the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

3 Jul 2023

Caffeine found to be most effective for treating birth asphyxia

Brain damage caused by oxygen deficiency at birth is one of the main causes of death in newborns worldwide. Using a small animal model, researchers from the University Hospital Bonn (UKB) and DZNE tested treatment with 25 different active agents.

3 Jul 2023

New correlation improves management and post-resuscitation care for patients

Newly-identified correlation could improve management and optimize post-resuscitation care for individual patients.

3 Jul 2023

How does space affect the immune system of astronauts?

Research explores the effects of microgravity and radiation on the immune system in space conditions. It emphasizes the need to understand these effects for future long-duration space missions and highlights knowledge gaps for further investigation.

2 Jul 2023

A new law is supposed to protect pregnant workers — but what if we don’t know how?

Vanessa Langness had always been a bit worried about the chemicals she worked with as a biomedical researcher, but when she got pregnant in October, her concerns grew.

30 Jun 2023

Researchers find new way to reduce risk of kidney injury in cardiac surgery patients

When a person has heart surgery, they're often managed on cardiopulmonary bypass.

29 Jun 2023

Study provides a comprehensive summary of benefits of exercise for people with Type 2 diabetes

An analysis on the positive effects of exercise on blood sugar levels in people with Type 2 diabetes shows that while all exercise helps, certain activities – and their timing – are extremely good for people's health.

28 Jun 2023

SickKids researchers discover new way to attack treatment-resistant TB infections

In the face of growing antibiotic resistance among bacterial infections, scientists at The Hospital for Sick Children (SickKids) have delved into the molecular science behind treatment-resistant tuberculosis.

28 Jun 2023

Newly identified enzyme could be a useful tool for creating anticancer drugs

Many of the drugs we use to treat cancer and infectious disease are ⎯ or derive from ⎯ natural products, but it's difficult to know exactly how nature assembles them.

27 Jun 2023

Smart Cuff: A single device to measure multiple cardiac functions

Surgical and intensive care patients face a higher risk of death and longer hospital stays because they are susceptible to both hypotension and hemodynamic instability – or unstable blood flow.

26 Jun 2023

New category of depression identified

Scientists at Stanford Medicine conducted a study describing a new category of depression - labeled the cognitive biotype - which accounts for 27% of depressed patients and is not effectively treated by commonly prescribed antidepressants.

23 Jun 2023

Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients

Researchers investigated whether black carbon particles in the blood increased COVID-19 severity.

23 Jun 2023

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

In the United States, sickle cell disease affects about 100,000 people and about 2 million Americans carry this genetic mutation.

22 Jun 2023

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

Live parental infant-directed singing has positive impacts on infants' emotional regulation, validation of the parent's role, and affect attunement, as identified in a systematic review of 21 studies. Benefits are observed in typically developing infants born at full term.

21 Jun 2023

Oxygen News and Research

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Base editing shows promise for treating sickle cell disease and beta thalassemia

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Caffeine found to be most effective for treating birth asphyxia

New correlation improves management and post-resuscitation care for patients

How does space affect the immune system of astronauts?

A new law is supposed to protect pregnant workers — but what if we don’t know how?

Researchers find new way to reduce risk of kidney injury in cardiac surgery patients

Study provides a comprehensive summary of benefits of exercise for people with Type 2 diabetes

SickKids researchers discover new way to attack treatment-resistant TB infections

Newly identified enzyme could be a useful tool for creating anticancer drugs

Smart Cuff: A single device to measure multiple cardiac functions

New category of depression identified

Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

The link between Covid-19 and Alzheimer's disease established

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

Elevated heart rate can induce a stroke in patients with highly blocked carotid arteries

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