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COVID-19 associated seizures may increase death risk in patients

COVID-19 can have damaging effects on multiple organs in the body, including the brain. A new study led by investigators at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) indicates that some hospitalized patients with COVID-19 experience non-convulsive seizures, which may put them at a higher risk of dying. The findings are published in the Annals of Neurology.

31 Mar 2021

Soft X-ray microscopy shows how viral pathogens penetrate human cells

How do viral pathogens succeed in penetrating human cells? Which cellular mechanisms do they use to multiply efficiently and, in doing so, how do they change the structure of their host cell? These questions are the focus of a pan-European research project called "Compact Cell-Imaging Device" (CoCID), in which Heidelberg scientists are playing a major role.

31 Mar 2021

Study shows how viral distribution of SARS-CoV-2 in the human body relates to tissue damage

Researchers have mapped the distribution of SARS-CoV-2, the virus that causes COVID-19, in deceased patients with the disease, and shed new light on how viral load relates to tissue damage.

31 Mar 2021

New Columbia University center provides specialized care for Lyme and tick-borne diseases

A new center that will provide specialized care for patients with Lyme disease and other tick-borne diseases will begin seeing patients this summer at Columbia University's Vagelos College of Physicians and Surgeons.

31 Mar 2021

New study may lead to GRK5-based therapies to prevent heart failure

The human heart works under high demand, constantly pumping oxygen-rich blood through the body. When faced with disease, however, fulfilling this demand can become increasingly difficult and harmful.

31 Mar 2021

New tool could help children with medical complexities avoid long hospitalizations

Too often, contends UMass Lowell faculty researcher Brenna Morse, children with complex chronic medical conditions spend days in the hospital undergoing tests for what could be a simple diagnosis.

30 Mar 2021

New technologies can screen for cervical cancer better than Pap smears

Emerging technologies can screen for cervical cancer better than Pap smears and, if widely used, could save lives both in developing nations and parts of countries, like the United States, where access to health care may be limited.

30 Mar 2021

Study compares performance of open-label placebo to blinded placebo in IBS patients

For decades, the power of the placebo effect was thought to lie in patients' belief that they were -- or at least, could be -- receiving a pharmacologically active treatment.

30 Mar 2021

Eco-bio-developmental model of emergent literacy helps identify risk factors of reading difficulties

Researchers at Cincinnati Children's Hospital Medical Center have developed a new framework for different factors influencing how a child's brain is "wired" to learn to read before kindergarten.

30 Mar 2021

Prime editing enables more precise correction of genetic problems than traditional CRISPR

The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say.

30 Mar 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

UT Southwestern researchers have identified factors that put patients with childhood-onset lupus at elevated risk for poor outcomes, such as end-stage renal disease or death, as they transition from pediatric to adult health care.

30 Mar 2021

UCLA receives grant to study the effectiveness of COVID-19 vaccines among health care workers

The David Geffen School of Medicine at UCLA has received a $4.9 million grant from the Centers for Disease Control and Prevention to study the effectiveness of COVID-19 vaccines among health care workers.

30 Mar 2021

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched.

30 Mar 2021

Strengths-based approach may attribute to positive outcomes in children with autism spectrum disorder

One of the biggest longitudinal research studies of its kind in the world led by The Hospital for Sick Children (SickKids) and the Centre for Addiction and Mental Health (CAMH) suggests that positive outcomes for children with autism spectrum disorder (ASD) are more common than previously thought.

30 Mar 2021

Despite targeted efforts, racial disparities persist in rural areas

In the last 20 years, Black adults living in rural areas of the United States have experienced high mortality rates due to diabetes, high blood pressure, heart disease, and stroke compared to white adults.

30 Mar 2021

Researchers study the physical effects of space travel on astronaut's heart

With NASA preparing to send humans to Mars in the 2030s, researchers are studying the physical effects of spending long periods in space.

30 Mar 2021

Study confirms the predictive value of molecular classification of hormone-sensitive breast cancer

Barcelona researchers at the Hospital Clínic-IDIBAPS Research Institute, the University of Barcelona and the SOLTI academic cancer research group have shown that the molecular classification of breast cancer, which divides it into four subtypes (Luminal A, Luminal B, HER2-enriched and Basal-like) is useful for predicting the benefits of treatment in patients with advanced hormone-sensitive breast cancer.

30 Mar 2021

Scientists study the sensitivity of SARS-CoV-2 variants to neutralize antibodies

The B.1.1.7 and B.1.351 variants of SARS-CoV-2 were first detected in the UK and South Africa respectively, and have since spread to many other countries.

29 Mar 2021

New study reports increased spread of B.1.1.7 variant in Houston, Texas

Research led by Jimmy Gollihar from the CCDC Army Research Laboratory-South in Austin, Texas found the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant B.1.1.7 —first detected last fall in England — increased in Houston, Texas. The B.1.1.7 variant is rapidly spreading with a case doubling time of 6.9 days.

29 Mar 2021

Hospital News and Research

COVID-19 associated seizures may increase death risk in patients

Soft X-ray microscopy shows how viral pathogens penetrate human cells

Study shows how viral distribution of SARS-CoV-2 in the human body relates to tissue damage

New Columbia University center provides specialized care for Lyme and tick-borne diseases

New study may lead to GRK5-based therapies to prevent heart failure

New tool could help children with medical complexities avoid long hospitalizations

New technologies can screen for cervical cancer better than Pap smears

Study compares performance of open-label placebo to blinded placebo in IBS patients

Eco-bio-developmental model of emergent literacy helps identify risk factors of reading difficulties

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

UCLA receives grant to study the effectiveness of COVID-19 vaccines among health care workers

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Strengths-based approach may attribute to positive outcomes in children with autism spectrum disorder

Despite targeted efforts, racial disparities persist in rural areas

Researchers study the physical effects of space travel on astronaut's heart

Study confirms the predictive value of molecular classification of hormone-sensitive breast cancer

Scientists study the sensitivity of SARS-CoV-2 variants to neutralize antibodies

New study reports increased spread of B.1.1.7 variant in Houston, Texas

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