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New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

With support from Amplicore, a University of Cincinnati spinoff biopharmaceutical company, researchers at UC have begun a Department of Defense-funded clinical trial that seeks a regenerative pharmaceutical solution for meniscal tears.

10 Jul 2023

Bystander CPR and defibrillation rates increase dramatically with volunteer responder systems

People suffering from sudden cardiac arrest are more likely to survive if cardiopulmonary resuscitation (CPR) and automated external defibrillators (AED) are used as soon as possible. However, in an out-of-hospital setting survival rates are low due to delays in care and low uptake of bystander CPR and AED use.

10 Jul 2023

Phosphorothioate backbone modification enhances aptamer-drug conjugate for pancreatic cancer therapy

Pancreatic cancer is a complex and deadly solid tumor that poses significant challenges for both diagnosis and treatment.

10 Jul 2023

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, promote standardization of testing across different laboratories, and improve patient care.

10 Jul 2023

High tumor monocyte content linked to better outcomes for esophageal cancer patients

A Ludwig Cancer Research study has discovered that the presence of relatively high numbers of immune cells known as monocytes in tumors is linked to better outcomes in esophageal cancer patients treated with a combination of chemotherapy and immunotherapy, or immunochemotherapy.

10 Jul 2023

Alcohol-related hepatitis hospitalizations increased dramatically during the pandemic

A boom in alcohol sales during the pandemic appears to have had dire consequences for some as hospital admissions for alcohol-related hepatitis, a life-threatening liver inflammation, increased dramatically, according to a study of national hospitalization data.

10 Jul 2023

Biomarkers in the brain could redefine mental health conditions

The study of biomarkers in the brain - powered by cutting-edge machine learning techniques - could redefine the way mental health conditions are categorized and diagnosed and lead to more effective, personalized treatments.

10 Jul 2023

Study: Flavor restrictions could make major progress in fighting youth vaping epidemic

Major progress could be made in fighting the youth vaping epidemic with a complete restriction on sweet flavorings and cooling agents in both cartridge and disposable e-cigarette devices, according to a new study from the Center for Tobacco Research at The Ohio State University Comprehensive Cancer Center.

10 Jul 2023

Few studies highlight the effects of lifestyle interventions on postpartum blood pressure

Hypertensive disorders of pregnancy such as preeclampsia and gestational hypertension occur in up to 10% of pregnancies and are associated with a three-fold increased risk of chronic hypertension and up to two-fold increased risk of cardiovascular disease when compared with healthy pregnancies.

10 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

In-person mindfulness courses may help prevent mental health problems

Adults who voluntarily take part in mindfulness courses are less likely to experience symptoms of anxiety and depression for at least six months after completing the programs, compared to adults who do not take part, a new analysis pooling data from 13 studies has confirmed.

10 Jul 2023

UVA researchers discover how 'hair cells' repair themselves

University of Virginia School of Medicine researchers have discovered how the cells that let us hear can repair themselves after being damaged.

10 Jul 2023

American Heart Association calls for shift to value-based payment system in cardiovascular care

The American Heart Association, a global force for longer, healthier lives for all, is advocating for a shift away from the current health care payment system in the U.S., which is primarily based on fee-for-service, to a value-based payment (VBP) system.

10 Jul 2023

Study finds critical gaps in care for people with Parkinson's disease

A new study has identified critical gaps in care for people with Parkinson's disease (PD) in the U.S., including disparities affecting women, people of color (those who identify as Asian, Black, Hispanic and Native American) and residents of rural areas.

10 Jul 2023

Real-time monitor can detect SARS-CoV-2 in indoor air within 5 minutes

Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses.

10 Jul 2023

Pandemic-born babies may have communication gaps, study finds

A study involving RCSI researchers has found that a small proportion of babies born early in the COVID-19 pandemic had gaps in their communication skills at age two and could benefit from additional support.

10 Jul 2023

Abnormal cortical folding linked to major depressive disorder

Major depressive disorder (MDD) is a complex and debilitating metal illness. Given its complex and widespread nature, MDD has been a subject of intense medical research.

10 Jul 2023

Depression after TBI may not be the same as depression related to other causes, study suggests

A new study led by Shan Siddiqi, MD, from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional major depressive disorder, with implications for patient treatment.

10 Jul 2023

PrecisionLife licenses OXEGENE dataset to develop personalized treatments for endometriosis

PrecisionLife, a leading techbio company driving precision medicine in complex chronic diseases, announced today a data access agreement with the University of Oxford to license the Oxford Endometriosis Gene (OXEGENE) dataset with the aim to develop new personalised treatments for endometriosis patients.

10 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

Medicine News and Research

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

Bystander CPR and defibrillation rates increase dramatically with volunteer responder systems

Phosphorothioate backbone modification enhances aptamer-drug conjugate for pancreatic cancer therapy

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

High tumor monocyte content linked to better outcomes for esophageal cancer patients

Alcohol-related hepatitis hospitalizations increased dramatically during the pandemic

Biomarkers in the brain could redefine mental health conditions

Study: Flavor restrictions could make major progress in fighting youth vaping epidemic

Few studies highlight the effects of lifestyle interventions on postpartum blood pressure

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

In-person mindfulness courses may help prevent mental health problems

UVA researchers discover how 'hair cells' repair themselves

American Heart Association calls for shift to value-based payment system in cardiovascular care

Study finds critical gaps in care for people with Parkinson's disease

Real-time monitor can detect SARS-CoV-2 in indoor air within 5 minutes

Pandemic-born babies may have communication gaps, study finds

Abnormal cortical folding linked to major depressive disorder

Depression after TBI may not be the same as depression related to other causes, study suggests

PrecisionLife licenses OXEGENE dataset to develop personalized treatments for endometriosis

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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