Immune System News and Research

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Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

A little STING could go a long way in helping treat or even avoid autoimmune diseases such as arthritis, type 1 diabetes and multiple sclerosis, researchers report.

10 Sep 2013

One-time treatment slows onset and progression of ALS, study finds

Studies of a therapy designed to treat amyotrophic lateral sclerosis suggest that the treatment dramatically slows onset and progression of the deadly disease, one of the most common neuromuscular disorders in the world.

10 Sep 2013

UCSF scientists identify new way to manipulate immune system from autoimmune diseases

Scientists from UC San Francisco have identified a new way to manipulate the immune system that may keep it from attacking the body-s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.

10 Sep 2013

Researchers investigate importance of STAT1 phosphorylation in NK cells

Since its discovery in the early 1990s, the protein STAT1 (Signal Transducer and Activator of Transcription 1) has been found to be central in passing signals across immune cells, ensuring that our bodies react quickly and appropriately to threats from viruses or other pathogens.

7 Sep 2013

Researchers start Phase I clinical trial of implantable vaccine for treatment of melanoma

A cross-disciplinary team of scientists, engineers, and clinicians announced today that they have begun a Phase I clinical trial of an implantable vaccine to treat melanoma, the most lethal form of skin cancer.

7 Sep 2013

PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

PaxVax Inc, which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced that it has commenced its Phase 3 clinical trial program for its single-dose oral cholera vaccine candidate, PXVX0200 (also known as CVD 103-HgR). Approximately 3,000 participants will be enrolled in this pivotal program, which is comprised of cholera challenge, safety, and immunogenicity studies.

7 Sep 2013

New Sponge-Based Therapeutic Cancer Vaccine Begins Human Clinicals

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6 Sep 2013

New Type 1 Diabetes competitive landscape map released by TechAtlas Group

TechAtlas Group has announced the release of the latest Type 1 Diabetes competitive landscape map. This particular landscape highlights 71 international companies with over 140 drugs and devices currently on the market and in development.

6 Sep 2013

Myeloid derived suppressor cells provide niche where cancer stem cells survive

The immune system is normally known for protecting the body from illness. But a subset of immune cells appear to be doing more harm than good.

6 Sep 2013

Researchers find safety mechanism in immune system in people with autoimmune diseases

Monash University researchers have found an important safety mechanism in the immune system that may malfunction in people with autoimmune diseases, such as Multiple Sclerosis, potentially paving the way for innovative treatments.

6 Sep 2013

UCSF to receive grant to study gene sequencing aimed at detecting disorders in newborns

UC San Francisco will receive $4.5 million over the next five years for a pilot project to assess whether large-scale gene sequencing aimed at detecting disorders and conditions can and should become a routine part of newborn testing.

6 Sep 2013

Scientists reveal structure of protein essential for triggering necroptosis

Scientists in Melbourne, Australia, have revealed the structure of a protein that is essential for triggering a form of programmed cell death called necroptosis, making possible the development of new drugs to treat chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis.

6 Sep 2013

Apoptosis can reactivate latent herpesviruses in dying cell

Researchers have found that apoptosis, a natural process of programmed cell death, can reactivate latent herpesviruses in the dying cell. The results of their research, which could have broad clinical significance since many cancer chemotherapies cause apoptosis, was published ahead of print in the Journal of Virology.

6 Sep 2013

Behavior problems in childhood may lead to inflammatory conditions later in life

Children with behavioral problems may be at risk of many chronic diseases in adulthood including heart disease, obesity, diabetes, as well as inflammatory illnesses (conditions which are caused by cell damage).

6 Sep 2013

Acute manic episodes linked to increased edema risk

Bipolar disorder patients admitted to hospital with a manic episode are at an increased risk for lower limb edema, compared with their peers with depressive or non-affective psychosis episodes, study findings show.

5 Sep 2013

Rigel Cuts 30 Jobs, Refocuses On Three Clinical Programs

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5 Sep 2013

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

A stressful pregnancy might be the last thing a future mother needs, but it is to her unborn baby that this stress spells real trouble. All because stress hormones (called glucocorticoids or GCs) can disturb normal foetal brain development, leading to behavioural and/or emotional problems later in life.

5 Sep 2013

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Rigel Pharmaceuticals, Inc. today announced its plans to focus the Company's resources on the completion of three lead clinical programs. These efforts include commencing a Phase 3 clinical study of fostamatinib, an oral SYK inhibitor, in Immune Thrombocytopenic Purpura pending discussions with regulatory agencies.

5 Sep 2013

Technology used to treat cancer also functions as micro rocket for spacecraft

Nanosatellites are smartphone-sized spacecraft that can perform simple, yet valuable, space missions. Dozens of these little vehicles are now tirelessly orbiting the earth performing valuable functions for NASA, the Department of Defense and even private companies.

5 Sep 2013

Study finds similar antibody levels among 4 PCV13 immunization schedules

The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in no statistically significant differences in antibody levels between the infants after the booster dose at 12 months of age for almost all serotypes, according to a study in the September 4 issue of JAMA.

5 Sep 2013

Immune System News and Research

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

One-time treatment slows onset and progression of ALS, study finds

UCSF scientists identify new way to manipulate immune system from autoimmune diseases

Researchers investigate importance of STAT1 phosphorylation in NK cells

Researchers start Phase I clinical trial of implantable vaccine for treatment of melanoma

PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

New Sponge-Based Therapeutic Cancer Vaccine Begins Human Clinicals

New Type 1 Diabetes competitive landscape map released by TechAtlas Group

Myeloid derived suppressor cells provide niche where cancer stem cells survive

Researchers find safety mechanism in immune system in people with autoimmune diseases

UCSF to receive grant to study gene sequencing aimed at detecting disorders in newborns

Scientists reveal structure of protein essential for triggering necroptosis

Apoptosis can reactivate latent herpesviruses in dying cell

Behavior problems in childhood may lead to inflammatory conditions later in life

Acute manic episodes linked to increased edema risk

Rigel Cuts 30 Jobs, Refocuses On Three Clinical Programs

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Technology used to treat cancer also functions as micro rocket for spacecraft

Study finds similar antibody levels among 4 PCV13 immunization schedules

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