Atherosclerosis News and Research

RSS

Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Study: Atorvastatin reduces inflammation, thrombogenesis in patients with acute ischemic stroke

The population of northeastern China has a high incidence of ischemic stroke. Previous studies have shown that intracranial large-artery atherosclerosis is one of the main causes of ischemic stroke, and that the mechanisms are related to inflammation and thrombosis of the affected arteries.

12 Sep 2013

Binghamton researcher hopes to give docs accurate way of determining patient's risk of heart attack

A Binghamton University researcher hopes to give doctors a more accurate way of determining a patient's risk of heart attack or stroke.

11 Sep 2013

MRI: A valuable tool for assessing risk of heart attack, stroke in diabetic patients

Whole-body MRI may serve as a valuable noninvasive tool for assessing the risk of heart attack and stroke in diabetic patients, according to a new study published online in the journal Radiology.

10 Sep 2013

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Case Western Reserve researchers have identified a genetic factor that blocks the blood vessel inflammation that can lead to heart attacks, strokes and other potentially life-threatening events.

5 Sep 2013

Sanofi, POZEN ink license agreement to commercialize PA8140 and PA32540 tablets in US

Sanofi US and POZEN Inc. announced the signing of an exclusive license agreement for the commercialization of POZEN's proprietary, investigational, coordinated-delivery tablets combining immediate-release omeprazole, a proton pump inhibitor, and enteric-coated aspirin in a single tablet ("PA"), PA8140 and PA32540.

5 Sep 2013

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Patients with coronary artery disease and low levels of "good cholesterol - or high-density lipoprotein - who were treated with a drug designed to increase HDL levels and reduce coronary plaque build-up, experienced no better results than those treated with placebo, according to research conducted by the Cleveland Clinic Coordinating Center for Clinical Research.

4 Sep 2013

Aliskiren does not slow progression of coronary atherosclerosis in prehypertension patients

Among patients with prehypertension and coronary artery disease, use of the renin (an enzyme secreted by the kidneys) inhibitor aliskiren, compared with placebo, did not result in improvement or slowing in the progression of coronary atherosclerosis, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the European Society of Cardiology Congress 2013.

4 Sep 2013

Increased risk caused by smoking is completely reversed after smoking cessation

Dr Dohi said: "Smokers are twice as likely to have a heart attack as people who have never smoked. Quitting smoking is the most important thing people can do to reduce their risk of cardiovascular disease. But until now, studies have not examined whether the increased risk caused by smoking is completely reversed after smoking cessation."

4 Sep 2013

AQUARIUS trial data shows Aliskiren reduced incidents of death, stroke, heart attack

Patients with clogged and hardened arteries who already have their blood pressure under control may benefit from an additional blood pressure-lowering medication, according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C5Research).

4 Sep 2013

Renin inhibitor aliskiren not effective in slowing progression of coronary atherosclerosis

3 Sep 2013

Aortic stenosis doubles in patients with family history of the condition

Aortic stenosis is the most common heart valve disease in the elderly. It is associated with congenital bicuspid aortic valve and previous rheumatic heart disease, but is also often caused by calcification of a normal valve. Calcification of a normal valve may be associated with atherosclerotic changes in the portion of the aorta closest to the valve.

2 Sep 2013

New angle for developing drugs to prevent thrombosis and heart attack

Platelets, which allow blood to clot, are at the heart of numerous cardiovascular problems, including heart attacks and stroke. New research has uncovered a key platelet protein that could offer a new angle for developing drugs to prevent thrombosis, or dangerous blood clots, in patients who are at high risk such as those with atherosclerosis or a history of heart problems.

31 Aug 2013

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Dezima Pharma, the biotechnology company developing innovative drugs in the field of dyslipidemia, announced today the initiation of a double blind, placebo controlled, Phase 2b dose ranging study of DEZ-001 (previously TA-8995), alone and in combination with statins, in order to study the effects on a wide range of lipids and other biomarkers of cardiovascular disease in patients with mild dyslipidemia.

30 Aug 2013

Athera Transfers Annexin A5 Project To Medirista

...

23 Aug 2013

Scientists grow cells that line blood vessels from human iPSCs

In a scientific first, Harvard Stem Cell Institute scientists have successfully grown the cells that line the blood vessels-called vascular endothelial cells-from human induced pluripotent stem cells (iPSCs), revealing new details about how these cells function.

23 Aug 2013

Sinai Hospital's chief of Surgery chosen to receive 2013 Innovator of the Year award

Mark R. Katlic, M.D., chief of Surgery at Sinai Hospital of Baltimore, has been selected to receive a 2013 Innovator of the Year award from The Daily Record. He was recognized for his pioneering work as the director of the groundbreaking Sinai Center for Geriatric Surgery.

22 Aug 2013

Researcher receives $3.52 million grant to study epicardial fat in arteries of heart

It's no secret that a diet high in fat and sugar can lead to extra fat around the waistline. But it's what the diet will do to a specific type of fat around the heart that caught the attention of a group of Creighton researchers.

16 Aug 2013

Proliferation of immune cells within plaques may be potential treatment target for atherosclerosis

New insights into the development of vulnerable atherosclerotic plaques could lead to better treatment or prevention of heart attacks and strokes.

12 Aug 2013

European authorisation of Aegerion Pharmaceuticals' Lojuxta brings hope for HoFH patients

Aegerion Pharmaceuticals, Inc., a biopharmaceutical company dedicated to the development and commercialisation of novel, life-altering therapies for patients with debilitating, often fatal, rare diseases, announced today that the European Commission has authorised Lojuxta (lomitapide) hard capsules as an adjunct to a low-fat diet and other lipid-lowering medicinal products with or without low density lipoprotein apheresis in adult patients with homozygous familial hypercholesterolaemia.

3 Aug 2013

Novel protein could lead to development of new drugs to treat variety of cancers

In cancer research, discovering a new protein that plays a role in cancer is like finding a key and a treasure map: follow the clues and eventually there could be a big reward. At least that's the hope from a new study published in the journal Nature that discovered a novel protein called ceramide-1 phosphate transport protein (CPTP) -- a finding that could eventually lead to the development of new drugs to treat a variety of cancers and other conditions involving inflammation and thrombosis, or blood clotting.

1 Aug 2013

Atherosclerosis News and Research

Further Reading

Study: Atorvastatin reduces inflammation, thrombogenesis in patients with acute ischemic stroke

Binghamton researcher hopes to give docs accurate way of determining patient's risk of heart attack

MRI: A valuable tool for assessing risk of heart attack, stroke in diabetic patients

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Sanofi, POZEN ink license agreement to commercialize PA8140 and PA32540 tablets in US

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Aliskiren does not slow progression of coronary atherosclerosis in prehypertension patients

Increased risk caused by smoking is completely reversed after smoking cessation

AQUARIUS trial data shows Aliskiren reduced incidents of death, stroke, heart attack

Renin inhibitor aliskiren not effective in slowing progression of coronary atherosclerosis

Aortic stenosis doubles in patients with family history of the condition

New angle for developing drugs to prevent thrombosis and heart attack

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Athera Transfers Annexin A5 Project To Medirista

Scientists grow cells that line blood vessels from human iPSCs

Sinai Hospital's chief of Surgery chosen to receive 2013 Innovator of the Year award

Researcher receives $3.52 million grant to study epicardial fat in arteries of heart

Proliferation of immune cells within plaques may be potential treatment target for atherosclerosis

European authorisation of Aegerion Pharmaceuticals' Lojuxta brings hope for HoFH patients

Novel protein could lead to development of new drugs to treat variety of cancers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News